[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100449984":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":27,"centralContacts":32,"locations":43,"responsibleParty":68,"collaborators":10,"id":71,"slug":10,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":72,"sex":78,"minAge":79,"maxAge":10,"enrollmentInfo":80,"targetDuration":83,"studyType":84,"phases":10,"briefSummary":85,"conditions":86,"keywords":10,"overallStatus":46,"whyStopped":10,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Infective endocarditis, surgical arm",null,"Patients with infective endocardits requiring valve surgery",[13],"Other: None, observational",{"label":15,"type":10,"description":16,"interventionNames":17},"Infective endocarditis, conservative arm","Patients with infective endocardits, not requiring valve surgery",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Valve disease, heart, surgically repaired","Patients requiring valve surgery",[13],[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"None, observational","Patients with infective endocarditis who do and do not undergo valve surgery compared with patientswithout endocarditis, who are operated on with similar valve surgery",[15,9,19],[28],{"name":29,"affiliation":30,"role":31},"Markus W Hollmann, MD,PhD,PhD","Amsterdam Academic Medical Center","PRINCIPAL_INVESTIGATOR",[33,38],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},"Jennifer S Breel, MPA,MSc","CONTACT","+31610019257","j.s.breel@amsterdamumc.nl",{"name":39,"role":35,"phone":40,"phoneExt":41,"email":42},"Henning Hermanns, MD,PhD","+31205669111","62533","h.hermanns@amsterdamumc.nl",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Academic Medical Center","RECRUITING","Amsterdam","North Holland","1105 AZ","Netherlands",{"type":52,"coordinates":53},"Point",[54,55],4.88969,52.37403,{"lat":55,"lon":54},[58,61,63,65,66],{"name":59,"role":35,"phone":60,"phoneExt":10,"email":37},"Jennifer S Breel, MPA,MSc.","+316 1001 9257",{"name":62,"role":35,"phone":40,"phoneExt":41,"email":42},"Henning Hermanns, MD, PhD",{"name":59,"role":64,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"name":39,"role":31,"phone":10,"phoneExt":10,"email":10},{"name":67,"role":31,"phone":10,"phoneExt":10,"email":10},"Susanne Eberl, MD,PhD",{"type":31,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Jennifer Breel","Research Coordinator","100449984",false,"NCT05139589","The ENDOCARDITIS AUMC Data Collection","The ENDOCARDITIS AUMC Data Collection : a Matched Cohort Study on Perioperative Coagulation in Conservatively and Surgically Treated Patients With Valvular Dysfunction, With and Without Infective Endocarditis","ENDO_AUMC","Inclusion Criteria:\n\n* Patients \\> 18 years\n* Dutch or English speaking\n* All patients with infective endocarditis admitted to Amsterdam UMC in the study period\n* All patients with infective endocarditis scheduled for cardiac valve surgery compared to a matched cohort of patients scheduled for similar surgery due to non-infectious indication in Amsterdam UMC in the same period\n\nExclusion Criteria:\n\n* Previous history of coagulation disorders","ALL","18 Years",{"count":81,"type":82},3000,"ESTIMATED","10 Years","OBSERVATIONAL","The investigators will compare patients with and without infective ndocarditis undergoing valve surgery and evaluate factors that may help optimise perioperative care of these high-risk patients.",[87,88,89],"Endocarditis","Coagulation Disorder","Valve Disease, Heart","2023-07-24",{"date":92,"type":93},"2023-07-25","ACTUAL",{"date":95,"type":82},"2023-08-06",{"date":97,"type":82},"2030-12-31",{"name":5,"class":6},1]