[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639657":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":21,"locations":10,"responsibleParty":27,"collaborators":31,"id":36,"slug":10,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":39,"acronym":10,"eligibilityCriteria":40,"healthyVolunteers":37,"sex":41,"minAge":42,"maxAge":10,"enrollmentInfo":43,"targetDuration":10,"studyType":46,"phases":10,"briefSummary":47,"conditions":48,"keywords":50,"overallStatus":55,"whyStopped":10,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":10},{"fullName":5,"class":6},"Zhongda Hospital","OTHER",[8,12,15,18],{"label":9,"type":10,"description":11,"interventionNames":10},"HH",null,"High induction blood pressure variability + High surgery blood pressure variability",{"label":13,"type":10,"description":14,"interventionNames":10},"HL","High induction blood pressure variability + Low surgery blood pressure variability",{"label":16,"type":10,"description":17,"interventionNames":10},"LH","Low induction blood pressure variability + High surgery blood pressure variability",{"label":19,"type":10,"description":20,"interventionNames":10},"LL","Low induction blood pressure variability + Low surgery blood pressure variability",[22],{"name":23,"role":24,"phone":25,"phoneExt":10,"email":26},"Lingjue Chen","CONTACT","+86 18851656227","760026195@qq.com",{"type":28,"investigatorFullName":29,"investigatorTitle":30,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Lanyue Zhu","Attending Physician",[32,34],{"name":33,"class":6},"Nanjing First Hospital, Nanjing Medical University",{"name":35,"class":6},"The First Affiliated Hospital of Anhui Medical University","100639657",false,"NCT07602465","The Impact of Blood Pressure Variability During the Induction and Surgical Periods on Postoperative Acute Kidney Injury","Inclusion Criteria:\n\n* Undergoing non-cardiac surgery；\n* Adult；\n\nExclusion Criteria:\n\n* Undergoing urological surgeries that partially directly affect kidney function (including relief of urinary tract obstruction, nephrectomy, or kidney transplantation);\n* Surgery duration less than 60 minutes;\n* Weight \\\u003C 30 kg or BMI \\> 35 kg\u002Fm2;\n* Patients who underwent reoperation within 7 days after surgery;\n* Surgeries not performed under general anesthesia;\n* ASA \\> IV;\n* No serum creatinine measurement available within 6 months before surgery (baseline value) or within 7 days after surgery;\n* Preexisting renal dysfunction or a diagnosis of chronic kidney disease before surgery (creatinine \\> 443 μmol\u002FL);\n* No invasive blood pressure monitoring during the anesthesia induction period, or missing more than 25% of intraoperative invasive blood pressure data collection.","ALL","18 Years",{"count":44,"type":45},5000,"ESTIMATED","OBSERVATIONAL","The goal of this multicenter retrospective cohort study aimed to explore the effect of BPV during anesthesia induction and surgery on the occurrence of postoperative AKI in non-cardiac surgery patients.",[49],"Acute Kidney Injury (AKI)",[51,52,53,54],"Acute kidney injury","Blood pressure variability","Anesthesia induction period","Non-cardiac surgery","NOT_YET_RECRUITING","2026-05-21",{"date":58,"type":59},"2026-05-27","ACTUAL",{"date":61,"type":45},"2026-06-01",{"date":63,"type":45},"2026-12-01",{"name":5,"class":6}]