[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613920":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":43,"responsibleParty":81,"collaborators":83,"id":91,"slug":11,"hasResults":92,"nctId":93,"briefTitle":94,"officialTitle":95,"acronym":11,"eligibilityCriteria":96,"healthyVolunteers":92,"sex":97,"minAge":98,"maxAge":99,"enrollmentInfo":100,"targetDuration":11,"studyType":103,"phases":104,"briefSummary":106,"conditions":107,"keywords":112,"overallStatus":119,"whyStopped":11,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":129},{"fullName":5,"class":6},"University of Alabama, Tuscaloosa","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Brief Behavioral Treatment for Insomnia (BBTI)","EXPERIMENTAL",null,[13],"Behavioral: BBTI",{"label":15,"type":16,"description":11,"interventionNames":17},"Brief Mindfulness Treatment (BMT)","ACTIVE_COMPARATOR",[18],"Behavioral: BMT",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"BEHAVIORAL","BBTI","4-week intervention delivered via telephone (once a week for 30 minutes)",[9],{"type":21,"name":26,"description":23,"armGroupLabels":27,"otherNames":11},"BMT",[15],[29],{"name":30,"affiliation":31,"role":32},"Dr. Shameka L Cody, PhD, AGNP-C, PMHNP-BC, FAAN","The University of Alabama Capstone College of Nursing","PRINCIPAL_INVESTIGATOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":11,"email":38},"Dr. Shameka L. Cody, PhD, AGNP-C, PMHNP-BC, FAAN","CONTACT","205 348 3374","slcody@ua.edu",{"name":40,"role":36,"phone":41,"phoneExt":11,"email":42},"Dr. Stephen Justin Thomas, PhD, DBSM, FSBSM","205 934 3367","sjthoma@uabmc.edu",[44,65],{"facility":45,"status":11,"city":46,"state":47,"zip":48,"country":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"The University of Alabama at Birmingham","Birmingham","Alabama","35233","United States",{"type":51,"coordinates":52},"Point",[53,54],-86.80249,33.52066,{"lat":54,"lon":53},[57,58,62],{"name":40,"role":36,"phone":41,"phoneExt":11,"email":42},{"name":59,"role":36,"phone":60,"phoneExt":11,"email":61},"Dr. David E. Vance, PhD, MGS, FAAN","205 934 7589","devance@uab.edu",{"name":63,"role":64,"phone":11,"phoneExt":11,"email":11},"Dr. Shu Chen, PhD","SUB_INVESTIGATOR",{"facility":66,"status":11,"city":67,"state":47,"zip":68,"country":49,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"The University of Alabama","Tuscaloosa","35401",{"type":51,"coordinates":70},[71,72],-87.56917,33.20984,{"lat":72,"lon":71},[75,76,79],{"name":35,"role":36,"phone":37,"phoneExt":11,"email":38},{"name":77,"role":36,"phone":11,"phoneExt":11,"email":78},"Dr. Mary L. Jacobs, PhD, MSPH, ABPP","jacob008@ua.edu",{"name":80,"role":64,"phone":11,"phoneExt":11,"email":11},"Dr. Chuong Bui, PhD",{"type":82,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR",[84,86,89],{"name":85,"class":6},"University of Alabama at Birmingham",{"name":87,"class":88},"National Institute on Aging (NIA)","NIH",{"name":90,"class":88},"NIH Office of AIDS Research (OAR)","100613920",false,"NCT07272863","The Impact of Brief Behavioral Treatment for Insomnia Versus Brief Mindfulness Treatment on Cognition and Sleep Health in Adults (Age 50+) With HIV","The Impact of BBTI on Cognition and Sleep Health in Older Adults With HIV","Inclusion Criteria:\n\n* must be age 50 or older\n* have a DSM-5 diagnostic criteria for insomnia including sleep difficulty that occurs at least 3 times per week and has been a problem for at least 3 consecutive months (indicated on the Structured Clinical Interview for Sleep Disorders, SCISD) during telephone screening\n* have a confirmed HIV diagnosis and a prescribed ART regimen for at least 12 months.\n\nExclusion Criteria:\n\n* unable to speak English\n* have a reported or documented (in medical records) diagnosis of AD or dementia\n* have severe neurocognitive impairment (\\>7 errors on the Short Portable Mental Status Questionnaire, SPMSQ) during telephone screening\n* have a history of a stroke\n* currently undergoing radiation\u002Fchemotherapy\n* reports a history of brain trauma with loss of consciousness greater than 30 minutes\n* have a learning disability\n* have a documented diagnosis of sleep apnea (in medical records)\n* reports use of a continuous positive airway pressure machine\n* have been identified as high risk for moderate to severe sleep apnea (Snoring, Tiredness, Observed sleep apnea, Pressure, BMI, Age, Neck circumference, and Gender, STOP BANG ≥ 5) during telephone screening\n* have restless leg syndrome and\u002For have narcolepsy\n* have a documented history of bipolar disorder or psychotic disorder\n* not be receiving efavirenz as part of their current ART regimen","ALL","50 Years","99 Years",{"count":101,"type":102},214,"ESTIMATED","INTERVENTIONAL",[105],"NA","The goal of this clinical trial is to examine the effects of a telephone-delivered Brief Behavioral Treatment Insomnia (BBTI) versus a Brief Mindfulness Treatment (BMT) on cognitive and sleep outcomes in older adults with HIV. The main questions it aims to answer are:\n\nWhat are the effects of BBTI vs BMT on self-reported and observed sleep outcomes in older adults with HIV and insomnia up to 1-year post-intervention? What are the effects of BBTI vs BMT on self-reported and observed cognitive comes in older adults with HIV and insomnia up to 1-year post-intervention? What is the association between Alzheimer's Disease biomarkers and sleep and cognitive outcomes in older adults with HIV receiving BBTI vs BMT?\n\nParticipants will:\n\n* Complete 4 weeks of telephone-delivered BBTI or BMT\n* Attend baseline, post-intervention, and 1-year post in-person visits for sleep and cognitive assessments\n* Have blood collected at all three time points",[108,109,110,111],"Insomnia","Cognition","Aging","HIV",[113,114,115,111,116,117,118],"insomnia","cognition","older adults","Alzheimer's Disease","brief behavioral treatment","randomized control trial","NOT_YET_RECRUITING","2026-05-07",{"date":122,"type":123},"2026-05-08","ACTUAL",{"date":125,"type":102},"2026-05",{"date":127,"type":102},"2030-09",{"name":5,"class":6},2]