The Impact of Glomerular Disorders on Bone Quality and Strength
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age5-55
SponsorColumbia University
About this trial
The primary objectives of this study are to: (1) determine the impact of glomerular disease on bone strength and (2) investigate the pathophysiologic underpinnings of impaired bone strength in glomerular disease.
Eligibility criteria
Qualifiers
CureGN participant or CureGN Eligible
First diagnostic kidney biopsy within 5 years of CureGN study enrollment
Access to first kidney biopsy report and/or slides or not being interested in study participation.
Males or females 5 to 55 years (premenopausal for women)
Disqualifiers
Chronic Dialysis
Solid organ transplantation
Lower extremity amputations or non-ambulatory
Malignancy requiring chemotherapy or metastatic to bone
Trial design
Treatments tested in this trial
- Dual-energy X-ray absorptiometry
- High Resolution Peripheral Quantitative Computed Tomography (HR-pQCT)
- Blood draw and Urine collection
- Questionnaires
Treatment groups
270 Participants
are divided into 1 treatment groupLocations
2Columbia University Irving Medical Center10032, New YorkNew York, United States
The Children's Hospital of Philadelphia19104, PhiladelphiaPennsylvania, United States
Sponsors and collaborators
Columbia University
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
Source ClinicalTrials.gov