[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594870":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":13,"locations":19,"responsibleParty":32,"collaborators":10,"id":35,"slug":10,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":39,"acronym":40,"eligibilityCriteria":41,"healthyVolunteers":42,"sex":43,"minAge":44,"maxAge":45,"enrollmentInfo":46,"targetDuration":10,"studyType":49,"phases":10,"briefSummary":50,"conditions":51,"keywords":55,"overallStatus":22,"whyStopped":10,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":66},{"fullName":5,"class":6},"Technical University of Madrid","OTHER",[8,11],{"label":9,"type":10,"description":10,"interventionNames":10},"Ex-athletes and continue to exercise regularly",null,{"label":12,"type":10,"description":10,"interventionNames":10},"Sedentary individuals",[14],{"name":15,"role":16,"phone":17,"phoneExt":10,"email":18},"Songxin Tang","CONTACT","+34 663002621","songxin.tang@alumnos.upm.es",[20],{"facility":21,"status":22,"city":23,"state":23,"zip":24,"country":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":10},"Faculty of Physical Activity and Sports Sciences (INEF)","RECRUITING","Madrid","28040","Spain",{"type":27,"coordinates":28},"Point",[29,30],-3.70256,40.4165,{"lat":30,"lon":29},{"type":33,"investigatorFullName":15,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Principal Investigator","100594870",false,"NCT07025070","The Link Between Physical Activity and Brain Health in Healthy Adults","The Link Between Strength and Endurance Training and Brain Health in Healthy Adults: A Comparative Study of Former Professional Athletes and Sedentary Individuals","MINA","Inclusion Criteria:\n\n* Group A: ex-athletes and continue to perform regular physical exercise (minimum 3 days\u002Fweek of moderate-vigorous intensity).\n* Group B: sedentary individuals, (i.e., perform \\\u003C150 min of moderate intensity exercise per week or IPAQ score\\\u003C600 MET min\u002Fweek).\n* In both groups (A and B) the conditions of physical exercise or sedentary lifestyle must have been maintained for at least 6 months prior to the evaluations.\n* Not having a history of neurological or psychiatric disorder or suffering from a serious medical condition\n\nExclusion Criteria:\n\n* Medical conditions that have a high risk of associated cognitive symptoms.\n* Severe head injury with loss of consciousness within the previous 5 years.\n* Alcoholism (\\>3 alcoholic drinks per day).\n* Chronic use of anxiolytics, neuroleptics, narcotics, anticonvulsants, or sedative hypnotics.\n* Hearing or visual impairment that would preclude testing\n* History of neurological disease with clinically relevant impact on cognition (e.g. cerebrovascular disease).\n* Incidental structural brain findings with impact on cognitive impairment or survival (e.g., malignant brain tumor).\n* Presence of severe systemic disease (e.g., cancer under treatment).\n* Consumption of anabolic substances.\n* Problems understanding spoken or written Spanish.\n* Those with pacemakers or metallic implants that may interfere with the MRI.",true,"ALL","40 Years","75 Years",{"count":47,"type":48},60,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to investigate the cross-sectional relationship between physical activity and brain health from a multiscale approach (neuropsychology, neuroimaging, peripheral biomarkers and genetics) in former athletes and sedentary individuals. The main question it aims to answer is:\n\nDo former athletes have better brain structure than sedentary people? Evaluating the differences in neurodegenerative processes between competitive training and sedentary and inactivity.",[52,53,54],"Alzheimer Disease","Inactivity","Preventive Therapy",[56],"physical activity","2025-06-09",{"date":59,"type":60},"2025-06-17","ACTUAL",{"date":62,"type":60},"2024-11-25",{"date":64,"type":48},"2026-09",{"name":5,"class":6},1]