[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100550592":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":10,"locations":23,"responsibleParty":63,"collaborators":65,"id":70,"slug":10,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":10,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":10,"enrollmentInfo":78,"targetDuration":10,"studyType":81,"phases":10,"briefSummary":82,"conditions":83,"keywords":10,"overallStatus":87,"whyStopped":10,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Guy's and St Thomas' NHS Foundation Trust","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pacing induced cardiomyopathy",null,"Patients who received a pacing device and developed pacing induced cardiomyopathy",[13],"Other: Machine learning",{"label":15,"type":10,"description":16,"interventionNames":17},"Non-pacing induced cardiomyopathy","Patients who received a pacing device and did not develop pacing induced cardiomyopathy",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Machine learning","Analysis of data with machine learning methods",[15,9],[24,43,53],{"facility":25,"status":10,"city":26,"state":10,"zip":27,"country":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"Guys' and St Thomas' Hospital NHS Trust","London","SE1 7EH","United Kingdom",{"type":30,"coordinates":31},"Point",[32,33],-0.12574,51.50853,{"lat":33,"lon":32},[36,40],{"name":37,"role":38,"phone":10,"phoneExt":10,"email":39},"Aldo Rinaldi, MD, MBBS, FRCP, FHRS","CONTACT","aldo.rinaldi@gstt.nhs.uk",{"name":41,"role":38,"phone":10,"phoneExt":10,"email":42},"Sandra Howell, MBBS, MSc, MSc","sandra.howell@gstt.nhs.uk",{"facility":44,"status":10,"city":26,"state":10,"zip":45,"country":28,"cosmosGeoPoint":46,"geoPoint":48,"contacts":49},"Kings' College London Healthcare Trust","SE5 9RS",{"type":30,"coordinates":47},[32,33],{"lat":33,"lon":32},[50],{"name":51,"role":38,"phone":10,"phoneExt":10,"email":52},"Francis Murgatroyd","francis.murgatroyd@nhs.net",{"facility":54,"status":10,"city":26,"state":10,"zip":55,"country":28,"cosmosGeoPoint":56,"geoPoint":58,"contacts":59},"Imperial College London Healthcare Trust","W12 0HS",{"type":30,"coordinates":57},[32,33],{"lat":33,"lon":32},[60],{"name":61,"role":38,"phone":10,"phoneExt":10,"email":62},"Steven Niederer, MPhil, PhD","s.niederer@imperial.ac.uk",{"type":64,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[66,68],{"name":67,"class":6},"Imperial College Healthcare NHS Trust",{"name":69,"class":6},"King's College Hospital NHS Trust","100550592",false,"NCT06449079","The PICM Risk Prediction Study - Application of AI to Pacing","Predictive Risk Algorithm for Development of Right Ventricular Pacing Induced Cardiomyopathy - a Step Towards Personalized Pacemaker Lead Deployment","Inclusion Criteria:\n\n* All patients who received a pacing device (VVI, DDD, ICD, leadless pacemaker) from the GSTT\u002FRBH\u002FKCH\u002FICH database in the last 10 years (from 01\u002F01\u002F2014)\n* All patients who are \\>18 years old.\n* Male and Female\n\nExclusion Criteria:\n\n* Patients who did not receive a pacing device (VVI, DDD, ICD, leadless pacemaker)\n* All patients \\\u003C18 years old\n* Patients with congenital heart disease\n* Patients who have received artificial heart valves or underwent cardiac bypass surgery\n* Patients who did not have an echocardiogram after receiving a pacing device","ALL","18 Years",{"count":79,"type":80},10000,"ESTIMATED","OBSERVATIONAL","Development of pacing induced cardiomyopathy (PICM) is correlated to a high morbidity as signified by an increase in heart failure admissions and mortality. At present a lack of data leads to a failure to identify patients who are at risk of PICM and would benefit from pre-selection to physiological pacing. In the light of the foregoing, there is an urgent need for novel non-invasive detection techniques which would aid risk stratification, offer a better understanding of the prevalence and incidence of PICM in individuals with pacing devices and the contribution of additional risk factors.",[84,85,86],"Heart Failure","Pacemaker-Induced Cardiomyopathy","Pacemaker Complication","NOT_YET_RECRUITING","2024-06-05",{"date":90,"type":91},"2024-06-07","ACTUAL",{"date":93,"type":80},"2024-07-30",{"date":95,"type":80},"2026-10-30",{"name":5,"class":6},3]