[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597765":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":34,"centralContacts":39,"locations":49,"responsibleParty":66,"collaborators":69,"id":71,"slug":43,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":43,"eligibilityCriteria":75,"healthyVolunteers":72,"sex":76,"minAge":77,"maxAge":43,"enrollmentInfo":78,"targetDuration":43,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":95,"overallStatus":52,"whyStopped":43,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Bach Mai Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Swan-Ganz-Guided Hemodynamic Resuscitation","EXPERIMENTAL","Participants in this arm will undergo invasive hemodynamic monitoring using a Swan-Ganz catheter upon admission to the intensive care unit. Hemodynamic variables, including right atrial pressure (RAP), pulmonary artery pressure (PAP), pulmonary capillary wedge pressure (PCWP), cardiac output (CO), cardiac power output (CPO), and mixed venous oxygen saturation (SvO₂) will be continuously measured and used to guide resuscitation. Management will follow a goal-directed algorithm targeting predefined thresholds for preload, afterload, contractility, and oxygen delivery. All patients will receive standard care for acute myocardial infarction, and no control or comparator arm is included in this study.",[13,14],"Device: Swan-Ganz IQ Pulmonary Arterial catheter","Device: Swan-Ganz IQ catheter",[16,27],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"DEVICE","Swan-Ganz IQ Pulmonary Arterial catheter","A pulmonary artery catheter (Swan-Ganz catheter) will be inserted via the right internal jugular or subclavian vein using a sterile technique and ultrasound guidance. The catheter is advanced into the pulmonary artery with real-time pressure waveform monitoring to confirm accurate positioning.\n\nOnce inserted, the catheter provides continuous invasive hemodynamic monitoring, including measurements of: Right atrial pressure (RAP), Pulmonary artery pressure (PAP), Pulmonary capillary wedge pressure (PCWP), Cardiac output (CO) by thermodilution, Mixed venous oxygen saturation (SvO₂).\n\nThese parameters are recorded at predefined intervals and used to guide goal-directed hemodynamic resuscitation. Clinical interventions such as vasopressor\u002Finotrope titration, fluid resuscitation, or ventilatory support will be adjusted accordingly. All procedures will follow institutional protocols and safety standards. Complications (e.g., arrhythmias, infection) will be monitored and managed per protocol.",[9],[22,23,24,25,26],"Flow-Directed Cathete","Plumonary Artery Catheter Swan-Ganz","Swan-Ganz catheterization","PAC","Invasive hemodynamic monitoring",{"type":17,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Swan-Ganz IQ catheter","A pulmonary artery catheter (Swan-Ganz catheter) will be inserted via the right internal jugular or subclavian vein using a sterile technique and ultrasound guidance. The catheter is advanced into the pulmonary artery with real-time pressure waveform monitoring to confirm accurate positioning.\n\nOnce inserted, the catheter provides continuous invasive hemodynamic monitoring, including measurements of: Right atrial pressure (RAP), Pulmonary artery pressure (PAP), Pulmonary capillary wedge pressure (PCWP), Cardiac output (CO) by thermodilution, Mixed venous oxygen saturation (SvO₂). These parameters are recorded at predefined intervals and used to guide goal-directed hemodynamic resuscitation. Clinical interventions such as vasopressor\u002Finotrope titration, fluid resuscitation, or ventilatory support will be adjusted accordingly. All procedures will follow institutional protocols and safety standards. Complications (e.g., arrhythmias, infection) will be monitored and managed per protocol.",[9],[32,33,24,26],"Cardiovascular Diagnostic Catheters","Pulmonary Artery Catheter",[35],{"name":36,"affiliation":37,"role":38},"Thang Xuan Pham, MD, PhD Candidate","Hanoi Medical University","PRINCIPAL_INVESTIGATOR",[40,45],{"name":36,"role":41,"phone":42,"phoneExt":43,"email":44},"CONTACT","+84357991992",null,"pxthanghmu92@gmail.com",{"name":46,"role":41,"phone":47,"phoneExt":43,"email":48},"Tuan Anh Nguyen, Prof.PhD","+8431115115","bstuanccbm@gmail.com",[50],{"facility":51,"status":52,"city":53,"state":43,"zip":54,"country":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"BachMai Hospital, Hanoi Medical University","RECRUITING","Hanoi","100000","Vietnam",{"type":57,"coordinates":58},"Point",[59,60],105.84117,21.0245,{"lat":60,"lon":59},[63],{"name":64,"role":41,"phone":65,"phoneExt":43,"email":44},"Thang Pham, MD, PhD Candidate","0357991992",{"type":38,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":43,"oldOrganization":43},"Thang Pham","Primary investigation",[70],{"name":37,"class":6},"100597765",false,"NCT07062744","The Role of Swan-Ganz Catheter in Hemodynamic Resuscitation for Patients With Cardiogenic Shock","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Provided written informed consent to participate in the study.\n* Diagnosed with cardiogenic shock due to acute myocardial infarction according to IABP-SHOCK II (2012) criteria:\n\n  * Systolic blood pressure (SBP) \\\u003C 90 mmHg for at least 30 minutes, or requiring vasopressor agents to maintain SBP \\> 90 mmHg.\n  * Evidence of end-organ hypoperfusion, indicated by at least one of the following: Altered mental status, Urine output \\\u003C 30 mL\u002Fhour, Cold extremities with mottled skin, Serum lactate level \\> 2 mmol\u002FL.\n\nExclusion Criteria:\n\n* Presence of cervical cellulitis.\n* Inability to identify neck anatomy or history of cervical radiotherapy.\n* Coagulopathy (INR \\> 1.5 and\u002For platelet count \\\u003C 50 G\u002FL).\n* End-stage chronic diseases, including: Advanced malignancy, advanced-stage HIV, bedridden patients for more than 3 months, decompensated liver cirrhosis (Child-Pugh class C).\n* Patients with cardiac arrest or mechanical complications such as myocardial rupture prior to Swan-Ganz catheterization.\n* Congenital heart defects or intracardiac shunts. Refusal of participation by the patient or their legal representative.","ALL","18 Years",{"count":79,"type":80},108,"ESTIMATED","INTERVENTIONAL",[83],"NA","This clinical trial examines whether the use of the Swan-Ganz catheter, a specialized pulmonary artery catheter, can improve hemodynamic management and treatment outcomes in patients experiencing cardiogenic shock due to acute myocardial infarction (AMI).\n\nCardiogenic shock is a critical condition marked by the heart's inability to supply adequate blood to the organs, often resulting from a severe heart attack. Despite advancements in care, the condition remains associated with high mortality. Effective monitoring of cardiovascular status is crucial in guiding timely and tailored treatment decisions.\n\nParticipants in this study will undergo advanced hemodynamic monitoring using the Swan-Ganz catheter, which provides continuous data on cardiac output and other key parameters. This information enables physicians to better assess circulatory function and adjust therapies accordingly.\n\nThe research will evaluate clinical characteristics, response to treatment, and 30-day outcomes in patients managed with this technique. The study also aims to identify factors associated with successful hemodynamic stabilization and potential complications related to catheter use.\n\nA total of 108 adult patients meeting specific eligibility criteria will be enrolled at Bach Mai Hospital over 3 years. Participation is voluntary, and all patients will continue to receive standard-of-care treatment. All personal and medical data will be handled with strict confidentiality.",[86,87,88,89,90,91,92,93,94],"Cardiogenic Shock","Pulmonary Artery Catheter Waveform Interpretation","Hemodynamic Management","Hemodynamic Optimization","Hemodynamic Monitoring","Acute Myocardial Infarction (AMI)","Critical Care, Intensive Care","Emergency","Cardio Vascular Disease",[96,33,97,98,99,100],"Swan-Ganz","Cardiogenic shock","Hemodynamic management","Invasive hemodynamic","Right Heart Catheter","2025-07-10",{"date":103,"type":104},"2025-07-14","ACTUAL",{"date":106,"type":104},"2025-05-27",{"date":108,"type":80},"2027-12-30",{"name":5,"class":6},1]