[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100591769":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":10,"centralContacts":26,"locations":35,"responsibleParty":52,"collaborators":10,"id":54,"slug":10,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":10,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":10,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":71,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Affiliated Hospital of Nantong University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental group",null,"Patients who meet the diagnosis of non-valvular atrial fibrillation and plan to receive sequential treatment of WATCHMAN FLX left atrial appendage occlusion and transcatheter atrial fibrillation ablation.",[13,14],"Procedure: left atrial appendage closure","Procedure: radiofrequency ablation",[16,23],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"PROCEDURE","left atrial appendage closure","Patients with atrial fibrillation underwent transcatheter radiofrequency cardiac ablation 1 month after left atrial appendage closure with WATCHMAN FLX",[9],[22],"left atrial appendage closure with WATCHMAN FLX",{"type":17,"name":24,"description":19,"armGroupLabels":25,"otherNames":10},"radiofrequency ablation",[9],[27,32],{"name":28,"role":29,"phone":30,"phoneExt":10,"email":31},"Qi Lu MD","CONTACT","+8613962989292","luqint@sina.com",{"name":33,"role":29,"phone":34,"phoneExt":10,"email":10},"Jian Zhang MD","13776926152",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Affiliated hospital of Nantong University","RECRUITING","Nantong","Jiangsu","226001","China",{"type":44,"coordinates":45},"Point",[46,47],120.87472,32.03028,{"lat":47,"lon":46},[50],{"name":28,"role":29,"phone":51,"phoneExt":10,"email":31},"13962989292",{"type":53,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100591769",false,"NCT06984731","The Safety and Efficacy of Radiofrequency Ablation After Left Atrial Appendage Occlusion.","Clinical Trial Protocol for Safety and Efficacy of Transcatheter Ablation After Left Atrial Appendicular Occlusion With WATCHMAN FLX","Inclusion Criteria:\n\n1. ≥18 years of age, diagnosed with nonvalvular atrial fibrillation;\n2. Meet the indications for receiving WATCHMAN FLX left atrial appendicular closure and transcatheter atrial fibrillation ablation;\n3. Preoperative imaging evaluation showed that the anatomical structure of the left atrial appendage was suitable for implantation with the WATCHMAN FLX device;\n4. The patient agrees to participate in the study and signs the informed consent.\n\nExclusion Criteria:\n\n1. valvular heart disease or other structural heart disease that causes atrial fibrillation;\n2. left auricular thrombus or acute thrombotic event was found before surgery;\n3. Patients with severe bleeding tendency or recent major bleeding events (such as massive gastrointestinal bleeding, cerebral hemorrhage, etc.);\n4. Patients who are unable to complete postoperative follow-up (such as life expectancy of less than 1 year or poor compliance);\n5. Other serious diseases (such as liver and kidney failure, active infection, etc.) were found in preoperative examination;\n6. Pregnant or lactating women.","ALL","18 Years","80 Years",{"count":64,"type":65},210,"ESTIMATED","OBSERVATIONAL","Objective: To evaluate the safety and efficacy of transcatheter atrial fibrillation ablation 1 month after WATCHMAN FLX left atrial appendage closure in patients with nonvalvular atrial fibrillation.",[69,70],"Cardiovascular Diseases","Arrhythmia",[72,73,74],"Atrial Fibrillation (AF)","Left Atrial Appendage closure with WATCHMAN device","Radiofrequency ablation","2025-05-18",{"date":77,"type":78},"2025-05-22","ACTUAL",{"date":80,"type":78},"2025-04-21",{"date":82,"type":65},"2028-06-01",{"name":5,"class":6},1]