[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635666":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":20,"locations":26,"responsibleParty":37,"collaborators":19,"id":41,"slug":19,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":42,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":19,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":19,"overallStatus":29,"whyStopped":19,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},{"fullName":5,"class":6},"National Children's Hospital, Vietnam","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Therapeutic Hypothermia","EXPERIMENTAL","Neonates diagnosed with hypoxic-ischemic encephalopathy (HIE) who meet the protocol-defined eligibility criteria will receive therapeutic hypothermia. Eligible infants are those born at or after 36 weeks of gestation, younger than 6 hours of age, and meeting the required clinical and biochemical criteria for therapeutic hypothermia according to the study protocol.",[13],"Procedure: Therapeutic Hypothermia",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"PROCEDURE","Therapeutic hypothermia will be administered to neonates with HIE according to the protocolized technical procedure developed and standardized in the study. The intervention is initiated in eligible neonates within 6 hours after birth and is performed with continuous clinical and neurologic monitoring as specified in the protocol.",[9],null,[21],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"DAT HUU TRAN","CONTACT","+84987836686","drtrandat1986@gmail.com",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"cosmosGeoPoint":19,"geoPoint":19,"contacts":34},"Vietnam National Children's Hospitalv","RECRUITING","Ha Nội","Hanoi","111111","Vietnam",[35],{"name":22,"role":23,"phone":36,"phoneExt":19,"email":25},"+84-987836686",{"type":38,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Dat Tran","Principal Investigator, MD, PhD","100635666",false,"NCT07555652","Therapeutic Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy in Vietnam","Efficacy of Controlled Therapeutic Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy (HIE)","HIE-TH Vietnam","Inclusion Criteria:\n\n* Neonates diagnosed with hypoxic-ischemic encephalopathy (HIE) at the Neonatal Center, National Children's Hospital\n* Gestational age ≥ 36 weeks\n* Assessed using the modified Sarnat staging within the first 0-6 hours after birth\n* Eligible for and\u002For treated with therapeutic hypothermia according to institutional protocol\n* Underwent clinical and paraclinical monitoring during hospitalization\n* Received brain magnetic resonance imaging (MRI) during the neonatal period (from 5 to 17 days of age)\n* Availability of complete medical records for data collection and analysis\n\nExclusion Criteria:\n\n* Presence of major congenital anomalies, particularly involving the central nervous system\n* Absence of brain MRI during the study period\n* Refusal of participation by parent(s) or legal guardian(s)","ALL","0 Hours","6 Hours",{"count":52,"type":53},120,"ESTIMATED","INTERVENTIONAL",[56],"NA","This study aims to evaluate the effectiveness of therapeutic hypothermia in neonates diagnosed with hypoxic-ischemic encephalopathy (HIE). The study focuses on assessing both short-term outcomes after treatment and long-term neurological outcomes following therapeutic hypothermia.",[59],"Hypoxic-ischemic Encephalopathy (HIE)","2026-04-21",{"date":62,"type":63},"2026-04-29","ACTUAL",{"date":65,"type":63},"2025-06-10",{"date":67,"type":53},"2028-02-01",{"name":5,"class":6},1]