[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100567215":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":25,"locations":31,"responsibleParty":46,"collaborators":12,"id":50,"slug":12,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":22,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":12,"enrollmentInfo":58,"targetDuration":12,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":33,"whyStopped":12,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Massachusetts General Hospital","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Usual Care","NO_INTERVENTION","Usual care at our institution involves a teaching visit with a nurse navigator and written handouts.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"THRIVE-CAR-T plus usual care","EXPERIMENTAL","Patients receiving the THRIVE-CAR-T intervention will receive usual care and will use the THRIVE-CAR-T digital application on an iPad when planned to receive CAR-T.",[18],"Behavioral: THRIVE-CAR-T",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"BEHAVIORAL","THRIVE-CAR-T","The intervention will begin several weeks prior to CAR-T cell therapy and will continue up until 30 days post CAR-T cell therapy. THRIVE-CAR-T is an educational and interactive digital application on an iPad for patients as they navigate receiving CAR-T. THRIVE-CAR-T is self-administered and provides education about the CAR-T cell therapy process, with several features to promote coping skills training informed by various well-established supportive psychotherapy strategies (e.g., cognitive behavior therapy, mindfulness, positive psychology), engagement, and health behavior change including gamification strategies, videos of patients who received CAR-T, and optional content.",[14],[26],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},"Patrick C Johnson, MD","CONTACT","6177244000","pcjohnson@mgh.harvard.edu",[32],{"facility":5,"status":33,"city":34,"state":35,"zip":36,"country":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"RECRUITING","Boston","Massachusetts","02114","United States",{"type":39,"coordinates":40},"Point",[41,42],-71.05977,42.35843,{"lat":42,"lon":41},[45],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},{"type":47,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"SPONSOR_INVESTIGATOR","Patrick C. Johnson, MD","Assistant Professor of Medicine","100567215",false,"NCT06665295","THRIVE-CAR-T Digital App","Randomized Controlled Trial of a Supportive Care Digital Application (THRIVE-CAR-T) for Patients Receiving CAR-T Cell Therapy","Inclusion Criteria:\n\n1. Age 18 years or older\n2. Ability to understand English\n3. Diagnosis of a hematologic malignancy\n4. Receiving autologous CAR-T at MGH with an FDA approved cellular therapy product\n\nExclusion Criteria:\n\n1. Impaired cognition or uncontrolled mental illness that prohibits the ability to provide informed consent based on the oncology clinician assessment\n2. Already participating in another supportive care clinical trial","ALL","18 Years",{"count":59,"type":60},100,"ESTIMATED","INTERVENTIONAL",[63],"NA","The goal of this clinical trial is to learn if a digital mobile application called THRIVE-CAR-T is helpful for the care of patients undergoing CAR-T cell therapy. The main question\\[s\\] it aims to answer are whether the THRIVE-CAR-T app is feasible and acceptable to patients.",[66],"CAR T-Cell Therapy",[68,69,70,71],"car-t cell therapy","digital application","mobile application","randomized controlled trial","2026-03-26",{"date":74,"type":75},"2026-04-01","ACTUAL",{"date":77,"type":75},"2024-10-17",{"date":79,"type":60},"2026-12-31",{"name":48,"class":6},1]