[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555143":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":34,"centralContacts":38,"locations":45,"responsibleParty":55,"collaborators":58,"id":68,"slug":11,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":11,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":11,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":88,"overallStatus":48,"whyStopped":11,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"German Institute of Human Nutrition","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Early Time-Restricted Eating","EXPERIMENTAL",null,[13],"Behavioral: Early Time-Restricted Eating",{"label":15,"type":10,"description":11,"interventionNames":16},"Late Time-Restricted Eating",[17],"Behavioral: Late Time-Restricted Eating",[19,27],{"type":20,"name":9,"description":21,"armGroupLabels":22,"otherNames":23},"BEHAVIORAL","Eat between 8:00 and 16:00 for 2 weeks",[9],[24,25,26],"early TRE","eTRE","eTRF",{"type":20,"name":15,"description":28,"armGroupLabels":29,"otherNames":30},"Eat between 13:00 and 21:00 for 2 weeks",[15],[31,32,33],"late TRE","lTRE","lTRF",[35],{"name":36,"affiliation":5,"role":37},"Soyoung Q Park, Prof. Dr.","PRINCIPAL_INVESTIGATOR",[39],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"Lara Ryan","CONTACT","33 200 88 - 2511","+ 49","lara.ryan@dife.de",[46],{"facility":47,"status":48,"city":49,"state":11,"zip":11,"country":50,"cosmosGeoPoint":11,"geoPoint":11,"contacts":51},"German Institute of Human Nutrition (DIfE)","RECRUITING","Nuthetal","Germany",[52],{"name":53,"role":41,"phone":11,"phoneExt":11,"email":54},"Bianca Weigel","DNN-Studie@dife.de",{"type":37,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Prof. Dr. Soyoung Q Park","Prof. Dr. Soyoung Q Park (Principal Investigator)",[59,62,64,66],{"name":60,"class":61},"Prof. Dr. Olga Ramich (German Institute of Human Nutrition)","UNKNOWN",{"name":63,"class":6},"Freie Universität Berlin",{"name":65,"class":6},"German Center for Diabetes Research",{"name":67,"class":6},"Charite University, Berlin, Germany","100555143",false,"NCT06508255","Time-restricted Eating and Cognition","Time-restricted Eating and Cognition (ChronoBEAT)","Inclusion Criteria:\n\n* right-handed\n* legally competent\n* physically and mentally healthy\n* BMI: 19-35 kg\u002Fm²\n* fluent in reading and speaking German\n\nExclusion Criteria:\n\n* weight change \\>5% of body weight during the last 3 months\n* pregnancy or breastfeeding\n* allergies (inclusion possible after consultation with study doctor)\n* history of cardiovascular disease (myocardial infarction, stroke, hypertension, hypotension) in the last year\n* severe psychiatric condition, including drug addiction and depression\n* impaired renal or liver function\n* dementia or other severely debilitating cognitive disease\n* history of or current eating disorders (e.g., Bulimia nervosa, Anorexia nervosa, Orthorexia nervosa, Binge-Eating disorder)\n* chronic diseases (e.g., Morbus Crohn, Colitis Ulcerosa)\n* metabolic disorders (e.g., metabolic syndrome, diabetes type 1 or 2)\n* hormonal imbalances (e.g., thyroid gland diseases)\n* consuming diseases (e.g., cancer, kachexie) in the last 2 years\n* surgical removal (partial removal) of the digestive organs (e.g., gastrectomy) or history of bariatric surgery\n* Autoimmune conditions or current infection\n* Blood clotting disorders (e.g., haemophilia)\n* Severe anemia\n* severe claustrophobia\n* blood donation four weeks prior to study entry\n* glucocorticoid therapy (oral)\n* anticoagulant medication (inclusion possible if medication can be paused)\n* taking medications that require regular eating\n* any medications or supplements known to affect sleep, circadian rhythms, immune activity or metabolism\n* taking weight loss, lipid or glucose-lowering medications (any medications that affects metabolism) i.e. metformin\n* pacemaker or other electrical implant\n* vaccination during the study course or in the two weeks' prior\n* immunosuppressive premedication\n* currently on a diet\u002Ffasting regime (or within 1 month)\n* professional athletes\n* nicotine consumption\n* drug abuse\n* alcohol consumption per week more than 14 beers (0,3l)\u002F wine (0,125l)\u002F sparkling wine (0,1l)\u002FSchnaps (4cl)\n* shift work\n* poor sleep quality (PSQI score \\> 10 at medical screening)\n* travel across more than one time zone one month before study or during study period\n* non-removable metallic implants\n* fear of blood draw",true,"FEMALE","18 Years","70 Years",{"count":79,"type":80},35,"ESTIMATED","INTERVENTIONAL",[83],"NA","This study aims to investigate how time-restricted eating (TRE), more specifically TRE at different times (early vs late in the day), influences brain activity, behavior, decision-making, food intake, physical activity, the gut microbiome and metabolic processes. The study intervention procedure is a replication of that described in Peters et al. (2021).",[86,87],"Time Restricted Eating","Intermittent Fasting",[89,90,91,92,93,94,95,96,97,98,99],"Time-restricted eating","Time-restricted feeding","Cognition","Decision-making","Behaviour","Brain Activity","Food Intake","Diet","Microbiome","Sleep","Physical Activity","2024-07-17",{"date":102,"type":103},"2024-07-18","ACTUAL",{"date":105,"type":103},"2024-05-17",{"date":107,"type":80},"2025-03",{"name":5,"class":6},1]