[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588013":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":31,"responsibleParty":54,"collaborators":10,"id":56,"slug":10,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":10,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":10,"studyType":68,"phases":10,"briefSummary":69,"conditions":70,"keywords":73,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Prospective Arm",null,"Children, young adolescents younger than 15 years, and young adults (15 to 39 years) with histologically confirmed patients with skeletal or extra-skeletal OS or ES with localized or metastatic disease stages.",[13],"Diagnostic Test: KLF factor (4 and 7)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","KLF factor (4 and 7)","Immunohistochemical staining of 4 um sections prepared from paraffin blocks using KLF factor (4 and 7) by automated immunostaining using the streptavidin-biotin technique.",[9],[21],{"name":22,"affiliation":23,"role":24},"Fatma S E Ebeid","Faculty of Medicine Ain Shams University","PRINCIPAL_INVESTIGATOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Fatma S E Ebeid, MD","CONTACT","01095569596","fatmaebeid@med.asu.edu.eg",[32,46],{"facility":5,"status":33,"city":34,"state":10,"zip":35,"country":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Cairo","11566","Egypt",{"type":38,"coordinates":39},"Point",[40,41],31.24967,30.06263,{"lat":41,"lon":40},[44],{"name":45,"role":28,"phone":29,"phoneExt":10,"email":30},"Fatma Ebeid",{"facility":47,"status":33,"city":34,"state":10,"zip":35,"country":36,"cosmosGeoPoint":48,"geoPoint":50,"contacts":51},"Faculty of Medicine Ain Shams Research Institute- Clinical Research Center (MASRI-CRC)",{"type":38,"coordinates":49},[40,41],{"lat":41,"lon":40},[52,53],{"name":45,"role":28,"phone":29,"phoneExt":10,"email":30},{"name":45,"role":24,"phone":10,"phoneExt":10,"email":10},{"type":55,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100588013",false,"NCT06935864","Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors","The Prognostic Value of Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors","Inclusion Criteria:\n\nAge: children, young adolescents younger than 15 years, and young adults (15 to 39 years) Gender: Males and female. Histologically confirmed patients with skeletal or extra-skeletal OS or ES. Both localized and metastatic disease stages.\n\nExclusion Criteria:\n\nPatients with second malignant bone sarcoma. Patients with benign bone tumors.","ALL","1 Month","39 Years",{"count":66,"type":67},30,"ESTIMATED","OBSERVATIONAL","The current study is to assess the prognostic value of Krüppel-like factors 4 and 7 in bone tumors, and its role in the disease progression.",[71,72],"Osteosarcoma in Children","Ewing Sarcoma of Bone or Soft Tissue",[74,75,76],"Bone Tumor","Osteosarcoma","Ewing sarcoma","2025-04-12",{"date":79,"type":80},"2025-04-20","ACTUAL",{"date":82,"type":80},"2024-08-16",{"date":84,"type":67},"2026-02",{"name":5,"class":6},2]