About this trial

Objectives:

1. To compare the immune response of patients with or without sepsis presenting to the ED with a(n) (suspected) infection. 2. To determine immune response aberrations that are associated with an increased risk of developing sepsis in patients presenting to the ED with a(n) (suspected) infection without sepsis. 3. To determine the long term cognitive and physical sequelae of sepsis after admission.

Eligibility criteria

Qualifiers

Age 18 years or higher

Presentation at the Emergency Department (ED)

Clinical suspicion of infection or earlier confirmed infection

Modified Early Warning Score (MEWS) of 2 or higher

Disqualifiers

No informed consent given

Trial design

Treatments tested in this trial

  • No intervention

Treatment groups

3,300 Participants
are divided into 1 treatment group

Locations

3
Flevoziekenhuis1315RA, Almere StadFlevoland, Netherlands
Amsterdam UMC, location AMC1105AZ, AmsterdamNorth Holland, Netherlands
Amsterdam UMC, location VUMC1081HZ, AmsterdamNorth Holland, Netherlands

Sponsors and collaborators

Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)

Lead sponsor

Amsterdam UMC, location AMC

Sponsor institution

Amsterdam UMC, location VUmc

Collaborator

Flevoziekenhuis

Collaborator