[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595699":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":13,"studyPopulation":13,"armGroups":20,"interventions":27,"overallOfficials":32,"centralContacts":39,"locations":46,"responsibleParty":65,"collaborators":13,"id":68,"slug":13,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":13,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":13,"maxAge":13,"enrollmentInfo":75,"targetDuration":13,"studyType":78,"phases":79,"briefSummary":80,"conditions":81,"keywords":13,"overallStatus":49,"whyStopped":13,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Chinese Academy of Medical Sciences, Fuwai Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Valve Academic Research Consortium-3","Outcomes were reported according to the VARC-3 criteria.Which include: Technical success: Evaluated immediately post-procedure (e.g., successful vascular access, device delivery, deployment, no immediate complications).\n\nDevice success: Includes successful valve function with acceptable hemodynamics and positioning.\n\nProcedural success: Includes 30-day outcomes, combining technical\u002Fdevice success and absence of major complications.","30 days after intervention",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":13,"primaryPurpose":17,"observationalModel":13,"timePerspective":13,"maskingInfo":18},"NA","SINGLE_GROUP","TREATMENT",{"masking":19,"maskingDescription":13,"whoMasked":13},"NONE",[21],{"label":22,"type":23,"description":24,"interventionNames":25},"Echo guided TAVR","EXPERIMENTAL","Patients received Echocardiography guided TAVR",[26],"Procedure: Echocardiography guided TAVR",[28],{"type":29,"name":30,"description":30,"armGroupLabels":31,"otherNames":13},"PROCEDURE","Echocardiography guided TAVR",[22],[33,36],{"name":34,"affiliation":5,"role":35},"Xiangbin Pan, MD","PRINCIPAL_INVESTIGATOR",{"name":37,"affiliation":5,"role":38},"Xu Wang, MD","STUDY_DIRECTOR",[40,44],{"name":34,"role":41,"phone":42,"phoneExt":13,"email":43},"CONTACT","+8688396666","panxiangbin@fuwaihospital.org",{"name":37,"role":41,"phone":45,"phoneExt":13,"email":13},"+86 88396655",[47],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Fuwai Hospital","RECRUITING","Beijing","Beijing Municipality","100037","China","CN",{"type":56,"coordinates":57},"Point",[58,59],116.39723,39.9075,{"lat":59,"lon":58},[62],{"name":63,"role":41,"phone":64,"phoneExt":13,"email":43},"Xiangbin Pan","088396666",{"type":35,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"Pan Xiangbin","Principle Investigator","100595699",false,"NCT07035847","Transaxillary TAVR With Solely Echocardiography Guidance","Transaxillary Transcatheter Aortic Valve Replacement With Pure Echocardiography Guidance","Inclusion Criteria:\n\n1. symptomatic severe AS determined by echocardiography and Doppler that requiring aortic valve replacement, defined as: mean gradient ≥40 mmHg, peak aortic velocity ≥4 m\u002Fs, and aortic valve area (AVA) ≤1 cm2 (or an indexed AVA ≤0.6 cm2\u002Fm2)\n2. suitable for Transaxillary TAVR\n\nExclusion Criteria:\n\n1. required hybrid procedures or concomitant interventions on other cardiac malformations\n2. inoperable due to extremely high surgical risk or severe comorbidities\n3. untreated clinically significant (\\>70% obstruction) proximal vessel coronary vascular disease amenable to revascularization\n4. previously undergone aortic valve replacement.","ALL",{"count":76,"type":77},20,"ESTIMATED","INTERVENTIONAL",[15],"This study aims to evaluate the safety and feasibility of performing transaxillary transcatheter aortic valve replacement (TA TAVR) guided solely by echocardiography in patients with severe aortic stenosis (AS).",[82],"Aortic Stenosis","2026-02-26",{"date":85,"type":86},"2026-02-27","ACTUAL",{"date":88,"type":86},"2024-10-01",{"date":90,"type":77},"2026-12-31",{"name":5,"class":6},1]