[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100559043":3},{"organization":4,"outcomesModule":7,"designInfo":21,"detailedDescription":32,"studyPopulation":20,"armGroups":33,"interventions":45,"overallOfficials":54,"centralContacts":58,"locations":68,"responsibleParty":86,"collaborators":20,"id":89,"slug":20,"hasResults":90,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":20,"eligibilityCriteria":94,"healthyVolunteers":90,"sex":95,"minAge":20,"maxAge":96,"enrollmentInfo":97,"targetDuration":20,"studyType":100,"phases":101,"briefSummary":103,"conditions":104,"keywords":20,"overallStatus":71,"whyStopped":20,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Assiut University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":20},[9,13],{"measure":10,"description":11,"timeFrame":12},"testis-to-ring distance in mm at the second stage","After either of transection or ligation of the spermatic vessels during the first stage of laparoscopic Fowler-Stephens orchidopexy, the location of the testis away from the internal inguinal ring (the testis-to-ring distance in mm) will be measured during the 2nd stage (degree of descent) 6 months after the first stage and compared among the two groups.","At 6 months after the first stage (during the second stage)",{"measure":14,"description":15,"timeFrame":12},"Testicular volume in mL","After either of transection or ligation of the spermatic vessels during the first stage of laparoscopic Fowler-Stephens orchidopexy, the testicular volume in mL will be assessed intraoperatively during the second stage (6 months after the first stage) and compared among the two groups.",[17],{"measure":18,"description":19,"timeFrame":12},"Operative time in minutes","After either of transection or ligation of the spermatic vessels during the first stage of laparoscopic Fowler-Stephens orchidopexy, the operative time in minutes of the second stage will be measured and compared among the two groups.",null,{"allocation":22,"interventionModel":23,"interventionModelDescription":20,"primaryPurpose":24,"observationalModel":20,"timePerspective":20,"maskingInfo":25},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":26,"maskingDescription":20,"whoMasked":27},"QUADRUPLE",[28,29,30,31],"PARTICIPANT","CARE_PROVIDER","INVESTIGATOR","OUTCOMES_ASSESSOR","Cryptorchidism is one of the most commin congenital deformities of male newborns, known as undescended testis (UDT). The incidence ranges according to gestational age, affecting 1.0-4.6% of full-term infants and 1.1-45% of preterm infants. (UDT) is a condition in which the testicles are not found at the base of the scrotum. Studies have shown that the undescended testicle has a potential of spontaneous descent during the first 3 months of life and is less likely to do so after 6 months of age. In almost 20% of cases the undescended testes are not palpable, increasing the difficulty of investigations and treatment, and 30% of these cases are also intra-abdominal. If UDT left untreated, it can cause histological alterations of the testicular cells and increasing of the risks of infertility.\n\nAs of treatment of UDT, laparoscopic surgery is ,for most surgeons, the preferred technique. Several techniques have been described for laparoscopic orchidopexy. After spermatic vascular transection, single-stage testicular descent fixing was carried out, as Fowler and Stephens (FSO) first described in 1959. Since 1996, a two-stage laparoscopic Fowler-Stephens technique involving preservation of the gubernacular vessels and performing an entirely laparoscopic second stage. The second stage is presently performed 6-9 months after the first.\n\nRecently, laparoscopic FSO has been adopted to treat high-level IATs, for its minimally invasive wound and acceptable success rate.",[34,40],{"label":35,"type":36,"description":37,"interventionNames":38},"Transection arm","ACTIVE_COMPARATOR","Transection of internal spermatic vessels in first stage laparoscopic Fowler-Stephens orchidopexy for intra-abdominal testis",[39],"Procedure: Transection of internal spermatic vessels in first stage laparoscopic Fowler-Stephens orchidopexy for intra-abdominal testis",{"label":41,"type":36,"description":42,"interventionNames":43},"Ligation arm","ligation of internal spermatic vessels in first stage laparoscopic Fowler-Stephens orchidopexy for intra-abdominal testis",[44],"Procedure: Ligation of internal spermatic vessels in first stage laparoscopic Fowler-Stephens orchidopexy for intra-abdominal testis",[46,50],{"type":47,"name":37,"description":48,"armGroupLabels":49,"otherNames":20},"PROCEDURE","Half of the patients will undergo transection of internal spermatic vessels in first stage laparoscopic Fowler-Stephens orchidopexy for intra-abdominal testis.",[35],{"type":47,"name":51,"description":52,"armGroupLabels":53,"otherNames":20},"Ligation of internal spermatic vessels in first stage laparoscopic Fowler-Stephens orchidopexy for intra-abdominal testis","Half of the patients will undergo ligation of internal spermatic vessels in first stage laparoscopic Fowler-Stephens orchidopexy for intra-abdominal testis",[41],[55],{"name":56,"affiliation":5,"role":57},"Mostafa M. Mostafa, MD, MSc, PhD","PRINCIPAL_INVESTIGATOR",[59,64],{"name":56,"role":60,"phone":61,"phoneExt":62,"email":63},"CONTACT","01000740478","+2","mostafaabdelaziz91@gmail.com",{"name":65,"role":60,"phone":66,"phoneExt":62,"email":67},"Ahmed H. Abolella, MD","01060636273","ahmed.hassan0032@med.aun.edu.eg",[69],{"facility":70,"status":71,"city":72,"state":73,"zip":74,"country":73,"countryCode":75,"cosmosGeoPoint":76,"geoPoint":81,"contacts":82},"Assiut University Urology Hospital","RECRUITING","Asyut","Egypt","71515","EG",{"type":77,"coordinates":78},"Point",[79,80],31.18368,27.18096,{"lat":80,"lon":79},[83],{"name":84,"role":60,"phone":85,"phoneExt":20,"email":63},"Mostafa M. Mostafa, M.D., M.Sc., Ph.D.","+201000740478",{"type":57,"investigatorFullName":87,"investigatorTitle":88,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Mostafa Mohamed Atef Abdelaziz Mostafa","Lecturer of Urology","100559043",false,"NCT06558994","Transection Versus Ligation of Internal Spermatic Vessels in Laparoscopic Fowler-Stephens Orchidopexy","Transection Versus Ligation of Internal Spermatic Vessels in First Stage Laparoscopic Fowler-Stephens Orchidopexy for Intra-abdominal Testis. Randomized Study","Inclusion Criteria:\n\nAll patients with Unilateral or Bilateral impalpable testis\n\nExclusion Criteria:\n\n1. Previous Laparotomy surgery\n2. Previous Ventriculo-peritoneal shunt\n3. Previous laparoscopy for impalpable testis (outside study)\n4. Previous Inguinal\u002FScrotal surgery\n5. Disorder of sexual differentiation\n6. Abnormal Karyotyping\n7. Intra-operative Inguinal testis\n8. Ipsilateral testis : Peeping\u002F Vas internal internal ring \u002F Vanished \u002F Streak \u002F Ovotestis \u002F Ovary.\n9. Contralateral : Streak\u002F Ovotestis\u002F Ovary","MALE","12 Years",{"count":98,"type":99},58,"ESTIMATED","INTERVENTIONAL",[102],"NA","This is a comparative study to see the outcome of yransection versus ligation of internal spermatic vessels in first stage laparoscopic Fowler-Stephens orchidopexy for intra-abdominal testis in assisting the descent of the testis to the base of scrotum during the second stage",[105],"Cryptorchidism","2026-02-10",{"date":108,"type":109},"2026-02-12","ACTUAL",{"date":111,"type":109},"2024-09-01",{"date":113,"type":99},"2027-09-01",{"name":5,"class":6},1]