[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598762":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":58,"centralContacts":62,"locations":63,"responsibleParty":82,"collaborators":62,"id":84,"slug":62,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":62,"eligibilityCriteria":89,"healthyVolunteers":85,"sex":90,"minAge":91,"maxAge":62,"enrollmentInfo":92,"targetDuration":62,"studyType":95,"phases":96,"briefSummary":98,"conditions":99,"keywords":62,"overallStatus":101,"whyStopped":62,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Roswell Park Cancer Institute","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Diagnostic (transperineal micro-ultrasound)","EXPERIMENTAL","Patients undergo transperineal micro-ultrasound imaging over 3 minutes followed by transrectal micro-ultrasound imaging during standard of care prostate biopsy. Patients also undergo MRI during screening.",[13,14,15],"Procedure: Biopsy of Prostate","Procedure: Magnetic Resonance Imaging","Procedure: Micro-ultrasound Imaging",[17,25,45,54],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"PROCEDURE","Biopsy of Prostate","Undergo standard of care prostate biopsy",[9],[23,24],"Prostate Biopsy","Prostatic Biopsy",{"type":18,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"Magnetic Resonance Imaging","Undergo MRI",[9],[30,31,32,33,34,35,36,37,38,39,40,41,42,43,44],"Magnetic Resonance","Magnetic Resonance Imaging (MRI)","Magnetic resonance imaging (procedure)","Magnetic Resonance Imaging Scan","Medical Imaging, Magnetic Resonance \u002F Nuclear Magnetic Resonance","MR","MR Imaging","MRI","MRI Scan","MRIs","NMR Imaging","NMRI","Nuclear Magnetic Resonance Imaging","sMRI","Structural MRI",{"type":18,"name":46,"description":47,"armGroupLabels":48,"otherNames":49},"Micro-ultrasound Imaging","Undergo transperineal micro-ultrasound imaging",[9],[50,51,52,53],"Micro ultrasound","Micro ultrasound Imaging","Micro-ultrasound","microUS",{"type":18,"name":46,"description":55,"armGroupLabels":56,"otherNames":57},"Undergo transrectal micro-ultrasound imaging",[9],[50,51,52,53],[59],{"name":60,"affiliation":5,"role":61},"Khurshid A Guru","PRINCIPAL_INVESTIGATOR",null,[64],{"facility":5,"status":62,"city":65,"state":66,"zip":67,"country":68,"cosmosGeoPoint":69,"geoPoint":74,"contacts":75},"Buffalo","New York","14263","United States",{"type":70,"coordinates":71},"Point",[72,73],-78.87837,42.88645,{"lat":73,"lon":72},[76,81],{"name":77,"role":78,"phone":79,"phoneExt":62,"email":80},"Khurshid A. Guru","CONTACT","716-845-6844","Khurshid.guru@roswellpark.org",{"name":77,"role":61,"phone":62,"phoneExt":62,"email":62},{"type":83,"investigatorFullName":62,"investigatorTitle":62,"investigatorAffiliation":62,"oldNameTitle":62,"oldOrganization":62},"SPONSOR","100598762",false,"NCT07075705","Transperineal Micro-ultrasound for the Detection of Prostate Cancer During Biopsy","Investigating the Feasibility of Using Transperineal Micro-Ultrasound to Detect Clinically Significant Prostate Cancer","Inclusion Criteria:\n\n* Men aged ≥ 18 years\n* Men scheduled for transrectal ultrasound guided prostate biopsy who have had a prebiopsy MRI. Therefore patients unable to have a prebiopsy MRI who have contraindications to MRI or unwilling to undergo MRI would be excluded\n* The participant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee\u002FInstitutional Review Board-approved written informed consent form before receiving any study-related procedure\n\nExclusion Criteria:\n\n* Any condition which in the investigator's opinion deems the participant an unsuitable candidate for study participation","MALE","18 Years",{"count":93,"type":94},138,"ESTIMATED","INTERVENTIONAL",[97],"NA","This clinical trial studies whether transperineal micro-ultrasound can be used to detect prostate cancer during biopsy. Transrectal ultrasound is often used during prostate biopsy. Transrectal ultrasound imaging is a procedure in which a probe that sends out high-energy sound waves is inserted into the rectum. The sound waves are bounced off internal tissues or organs and make echoes. The echoes form a picture of body tissue called a sonogram. Transrectal ultrasound is used to look for abnormalities in the rectum and nearby structures, including the prostate. The images are used to guide the prostate biopsy. Transperineal micro-ultrasound is completed by placing a probe over the skin between the scrotum and anus (perineum). It is a high-resolution ultrasound at 29 megahertz (MHz) (compared to traditional ultrasound at 6-9 MHz). This higher frequency allows for an improved spatial resolution. This improved spatial resolution is approximately the diameter of a prostatic duct, and therefore, may be able to visualize slight changes in the structure of prostatic ducts that are not possible with standard transrectal ultrasound. Transperineal micro-ultrasound may be more effective in detecting prostate cancer during biopsy.",[100],"Prostate Carcinoma","NOT_YET_RECRUITING","2026-05-21",{"date":104,"type":105},"2026-05-22","ACTUAL",{"date":107,"type":94},"2026-07-15",{"date":109,"type":94},"2027-01-15",{"name":5,"class":6},1]