To investigate whether patients with cerebral vasospasm associated with aneurysmal subarachnoid hemorrhage have a better prognosis with intrathecal nicardipine injection via extraventricular drainage or lumbar drainage.
Age 18-80.
Spontaneous SAH confirmed by head CT.
Saccular brain aneurysm is identified and treated, either surgically or endovascularly.
SAH Fisher grade >1 or modified Fisher grade >0.
Hunt-Hess Grade 5 or WFNS Grade 5 (no clinical improvement after EVD placement for acute hydrocephalus).
Bacterial or distal aneurysms without subarachnoid hemorrhage in the basal cisterns.
The treating physician determines that the culprit aneurysm has not been fully repaired, with a very high likelihood of rebleeding in the near term.
History of head trauma within the past 3 months.
The Affiliated Hospital Of Guizhou Medical University
Lead sponsor