Treatment With Endovascular Intervention for STroke Patients With Existing Disability
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Cincinnati
About this trial
TESTED will compare the risks and benefits of endovascular thrombectomy (EVT) to medical management (no EVT) in ischemic stroke patients who have a blockage in one of the large blood vessels in the brain and have a moderate-to-severe disability prior to their stroke.
Eligibility criteria
Qualifiers
Adult patients (≥18 years)
Moderate-to-severe pre-stroke functional disability, defined as mRS 3-4, for at least 3 months prior to stroke onset
Presenting to study hospital within 24 hours of last known well time
Diagnosis of acute ischemic stroke
Disqualifiers
Known diagnosis of a terminal cancer or terminal illness at the time of stroke
Assessment of pre-stroke functional status cannot be performed during the hospital stay
Pre-stroke disability deemed temporary in the investigator's opinion (for example, recovering from a general medical illness or traumatic bodily injury)
Trial design
Treatments tested in this trial
- Endovascular Stroke Treatment
- Medical Management
Treatment groups
1,060 Participants
are divided into 1 treatment groupLocations
25Arizona
HonorHealth85013, Phoenix United States
California
Kaiser Permanente Los Angeles Medical Center90027, Los Angeles United States
University of California at Los Angeles90095, Los Angeles United States
Standford94305, Palo Alto United States
Sponsors and collaborators
University of Cincinnati
Lead sponsor
Patient-Centered Outcomes Research Institute
Collaborator
University of California, Los Angeles
Collaborator
Icahn School of Medicine at Mount Sinai
Collaborator
Source ClinicalTrials.gov