Trial of Combined Obstetric Carrier Screening and Hereditary Cancer Screening

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-55
SponsorWeill Medical College of Cornell University

About this trial

The investigators hypothesize that pregnancy and preconception care may be a feasible and effective time to offer inherited cancer risk screening. This study will assess interest in cancer genetic testing among patients receiving routine prenatal or preconception/fertility care. The goal is to evaluate the acceptability of BRCA1/2 testing when offered alongside standard prenatal genetic screening. The study will also explore whether universal screening in this population could support early cancer prevention and be cost-effective, especially among underserved populations.

Eligibility criteria

Qualifiers

Age 18 years - 55 years

Pregnant patients receiving obstetrical-related care or receiving preconception/fertility care at a WCM-affiliated enrollment site.

Patients who have elected to undergo OCS with the WCM-affiliated obstetrics provider

Patients with prior OCS but planned to repeat OCS are eligible

Disqualifiers

Patients who have previously completed a multigene hereditary cancer syndrome panel

Patients who have a hematologic cancer or hematologic pre-cancer

Patients who have a history of an autologous bone marrow transplant

Trial design

Treatments tested in this trial

  • MyRisk Hereditary Cancer Test

Treatment groups

550 Participants
are divided into 2 treatment groups

Locations

5
NewYork-Presbyterian Weill Cornell Medicine11215, BrooklynNew York, United States
Reproductive Medicine11201, BrooklynNew York, United States
Reproductive Medicine10021, New YorkNew York, United States
Weill Cornell Medicine10065, New YorkNew York, United States

Sponsors and collaborators

Weill Medical College of Cornell University

Lead sponsor

Myriad Genetics, Inc.

Collaborator