[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597982":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":49,"collaborators":25,"id":52,"slug":25,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":53,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":25,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"The First Affiliated Hospital of Guangzhou Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Non-intubated group","EXPERIMENTAL","Surgical procedure: non-intubated tracheal and carinal reconstruction",[13],"Procedure: non-intubated tracheal and carinal reconstruction",{"label":15,"type":16,"description":17,"interventionNames":18},"Intubated group","ACTIVE_COMPARATOR","Surgical procedure: intubated tracheal and carinal reconstruction",[19],"Procedure: intubated tracheal and carinal reconstruction",[21,26],{"type":22,"name":23,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","non-intubated tracheal and carinal reconstruction",[9],null,{"type":22,"name":27,"description":27,"armGroupLabels":28,"otherNames":25},"intubated tracheal and carinal reconstruction",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Shuben Li","CONTACT","86+(020) 8306 2114","13500030280@163.com",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":25},"the First Affiliated Hospital of Guangzhou Medical University","RECRUITING","Guangdong","Gaungzhou","510120","China",{"type":44,"coordinates":45},"Point",[46,47],129.33635,42.76832,{"lat":47,"lon":46},{"type":50,"investigatorFullName":31,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Deputy Director","100597982",false,"NCT07065565","Tubeless Tracheal and Carinal Reconstruction","Non-intubated vs Intubated Anesthesia for Tracheal and Carinal Reconstruction","NOVA-01","Inclusion Criteria:\n\n1. Airway diseases were diagnosed by chest enhanced CT and bronchoscopy\n2. The patients with age ≥ 18 and ≤ 80 years old\n3. ASA (American Society of Anesthesiologists) stage: I-III\n4. sign the informed consent. -\n\nExclusion Criteria:\n\n1. The patients have proved history of congestive heart failure, angina without good control with medicine; ECG-proved penetrating myocardial infarction; hypertension with bad control; valvulopathy with clinical significance; arrhythmia with high risk and out of control\n2. The patients have severe systematic intercurrent disease, such as active infection or poorly controlled diabetes; coagulation disorders; hemorrhagic tendency or under treatment of thrombolysis or anticoagulant therapy\n3. Airway anatomical abnormalities due to a history of surgery\n4. Patients present with other malignancy","ALL","18 Years","80 Years",{"count":63,"type":64},176,"ESTIMATED","INTERVENTIONAL",[67],"NA","In recent year, non-intubated anesthesia had emerged as an available alternative for thoracic procedure. Whether non-intubated tracheal\u002Fcarinal reconstruction confers distinct perioperative advantages over the conventional intubated approach remains uncertain. The purpose of this study was to evaluate the safety and perioperative outcomes of non-intubated versus intubated approaches in tracheal and carinal reconstruction.",[70,71],"Tracheal Disease","Airway Disease",[73,74,75,76],"non-intubated anesthesia","airway disease","tracheal reconstruction","carinal reconstruction","2025-07-04",{"date":79,"type":80},"2025-07-15","ACTUAL",{"date":82,"type":80},"2025-03-26",{"date":84,"type":64},"2028-08-31",{"name":31,"class":6},1]