[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597985":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":49,"collaborators":53,"id":55,"slug":25,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":56,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":25,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":77,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"The First Affiliated Hospital of Guangzhou Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Non-intubated group","EXPERIMENTAL","Patients received tubeless VATS for mediastinal neoplasm",[13],"Procedure: Non-intubated VATS for mediastinal neoplasm",{"label":15,"type":16,"description":17,"interventionNames":18},"Intubated group","ACTIVE_COMPARATOR","Patients received VATS mediastinal neoplasm resection under intubated general anesthesia.",[19],"Procedure: Intubated VATS for mediastinal neoplasm",[21,26],{"type":22,"name":23,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Non-intubated VATS for mediastinal neoplasm",[9],null,{"type":22,"name":27,"description":27,"armGroupLabels":28,"otherNames":25},"Intubated VATS for mediastinal neoplasm",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Shuben Li, Deputy Director","CONTACT","86(020) 8306 2114","13500030280@163.com",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":25},"the First Affiliated Hospital of Guangzhou Medical University","RECRUITING","Guangzhou","Guangdong","510120","China",{"type":44,"coordinates":45},"Point",[46,47],113.25,23.11667,{"lat":47,"lon":46},{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Shuben Li","Deputy Director",[54],{"name":5,"class":6},"100597985",false,"NCT07065604","Tubeless VATS for Mediastinal Neoplasm","A Randomized Controlled Trial of Non-intubated Versus Intubated VATS for Mediastinal Neoplasm","NOVA-02","Inclusion Criteria:\n\n1. Mediastinal neoplasm was diagnosed by chest enhanced CT\n2. The patients with age ≥ 18 and ≤ 80 years old\n3. The patients whose tumor diameter was \\\u003C6 cm\n4. ASA grade: I-III\n5. The patients should understand the research and sign the informed consent\n\nExclusion Criteria:\n\n1. Imaging examinations revealed that the tumor had invaded adjacent organs, with evidence of pleural or pericardial dissemination, as well as lymphatic and\u002For hematogenous metastases\n2. Patients with a confirmed history of congestive heart failure, poorly controlled angina despite medical therapy, electrocardiogram-confirmed myocardial infarction with transmural involvement, uncontrolled hypertension, clinically significant valvular heart disease, or high-risk arrhythmias not adequately managed\n3. Patients with concurrent active malignancies","ALL","18 Years","80 Years",{"count":66,"type":67},132,"ESTIMATED","INTERVENTIONAL",[70],"NA","In recent year, non-intubated anesthesia had emerged as an available and promising alternative for thoracic procedure. However, its safety and feasibility in video-assisted thoracoscopic surgery (VATS) for mediastinal neoplasm remain controversial. This randomized controlled trial is designed to evaluate the impact of the non-intubated approach on surgical and perioperative outcomes in patients undergoing mediastinal neoplasm resection.",[73,74,75,76],"Mediastinal Neoplasm","VATS","Tubeless","Non-intubated Anesthesia",[76,75,73,74],"2025-07-04",{"date":80,"type":81},"2025-07-15","ACTUAL",{"date":83,"type":81},"2025-03-26",{"date":85,"type":67},"2028-08-31",{"name":51,"class":6},1]