About this trial

The aim of this multicenter randomized clinical trial is to compare the tunneling technique of PICC insertion with the non-tunneled insertion technique in the incidence of the combined or isolated outcome of catheter-related bloodstream primary infection, thrombosis, obstruction, and accidental dislodgement in the adult population within a period of up to 30 days.

Eligibility criteria

Qualifiers

adult patients (>= 18 years old) admitted to medical clinics, surgical clinics, or ICU, who have an indication for PICC insertion;

Disqualifiers

patients with Chronic Kidney Disease, whether dialytic or not;

patients in critical or unstable condition characterized by the need for intubation, respiratory rate <8 or >35 breaths per minute, oxygen saturation <90%, heart rate <40 or >140 beats per minute, systolic blood pressure <90mmHg, decreased Glasgow Coma Scale >2 points, or prolonged (>5 minutes) or repeated seizures;

patients with cognitive deficits that impair their understanding of the study and do not have a responsible party to assist in this stage.

Trial design

Treatments tested in this trial

  • Subcutaneous tunnelling
  • Non-tunnelling

Treatment groups

840 Participants
are divided into 2 treatment groups

Locations

1
Hospital de Clínicas de Porto Alegre Porto Alegre Brazil

Sponsors and collaborators

Hospital de Clinicas de Porto Alegre

Lead sponsor

Hospital Moinhos de Vento

Collaborator

Irmandade Santa Casa de Misericórdia de Porto Alegre

Collaborator