[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100265401":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":10,"locations":20,"responsibleParty":207,"collaborators":209,"id":213,"slug":10,"hasResults":214,"nctId":215,"briefTitle":216,"officialTitle":216,"acronym":217,"eligibilityCriteria":218,"healthyVolunteers":214,"sex":219,"minAge":220,"maxAge":221,"enrollmentInfo":222,"targetDuration":10,"studyType":225,"phases":10,"briefSummary":226,"conditions":227,"keywords":231,"overallStatus":23,"whyStopped":10,"lastUpdateSubmitDate":234,"lastUpdatePostDateStruct":235,"startDateStruct":238,"completionDateStruct":240,"leadSponsor":242,"locationsCount":243},{"fullName":5,"class":6},"National Institute of Allergy and Infectious Diseases (NIAID)","NIH",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Group 1: Detectable C-peptide by MMTT",null,"Participants with detectable C-peptide at their:\n\n* Last Immune Tolerance Network (ITN) T1DM week 104 study visit,\n* Last AbATE (NCT00129259) follow-up visit, or\n* Last ITN066AI T1DES visit\n\nDetectable C-peptide is defined as a value above the lower limit of detection.",{"label":13,"type":10,"description":14,"interventionNames":10},"Group 2:Undetectable C-peptide by MMTT","Participants without detectable C-peptide at their:\n\n* Last ITN T1DM week 104 study visit,\n* Last AbATE follow-up visit, or last\n* ITN066AI T1DES visit\n\nUndetectable C-peptide is defined as a value below the lower limit of detection.",[16],{"name":17,"affiliation":18,"role":19},"Linda A. 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MD",{"facility":154,"status":23,"city":155,"state":156,"zip":157,"country":27,"cosmosGeoPoint":158,"geoPoint":162,"contacts":163},"University of Minnesota","Minneapolis","Minnesota","55454",{"type":29,"coordinates":159},[160,161],-93.26384,44.97997,{"lat":161,"lon":160},[164,168],{"name":165,"role":37,"phone":166,"phoneExt":10,"email":167},"Anne Street","612-625-9709","stree065@umn.edu",{"name":169,"role":42,"phone":10,"phoneExt":10,"email":10},"Antoinette Moran, MD",{"facility":171,"status":78,"city":172,"state":173,"zip":174,"country":27,"cosmosGeoPoint":175,"geoPoint":179,"contacts":10},"Children's Mercy Hospital","Kansas City","Missouri","64108",{"type":29,"coordinates":176},[177,178],-94.57857,39.09973,{"lat":178,"lon":177},{"facility":181,"status":78,"city":182,"state":183,"zip":184,"country":27,"cosmosGeoPoint":185,"geoPoint":189,"contacts":10},"Sanford Research","Sioux Falls","South 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to sign informed consent\u002Fassent (as applicable for children).\n\nExclusion Criteria:\n\n* Any medical condition that in the opinion of the principal investigator would interfere with safe completion of the trial; or\n* Inability to comply with the study visit schedule and required assessments.","ALL","8 Years","35 Years",{"count":223,"type":224},111,"ESTIMATED","OBSERVATIONAL","This is a multi-center, prospective, non-interventional study that focuses on the long- term effects following participation in selected ITN new-onset Type1 Diabetes Mellitus studies with immunomodulatory agents (T1DM, T1D).\n\nThis observational study will:\n\n* follow participants to determine how long they continue to produce insulin, and\n* will also assess how changes in the immune system over time relate to the ability to produce insulin.\n\nThis information could help design better therapies for type 1 diabetes in the future.",[228,229,230],"Type 1 Diabetes 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