Ultrasound-guided Thermal Ablation for Recurrent Thyroid Cancer
ConditionRecurrent Thyroid Cancer
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorChinese PLA General Hospital
About this trial
To evaluate the long-term outcomes of ultrasound-guided thermal ablation for recurrent thyroid cancer
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
patient received thyroidectomy for thyroid cancer
recurrent lesions were pathologically proven to be malignant by core-needle biopsy or fine needle aspiration
no evidence of distant metastases.
follow-up period ≥12 months
Disqualifiers
coagulation disorder, serious heart, respiratory, liver, or renal failure
dysfunction of the vocal cord on the opposite side
Trial population
patients with recurrent thyroid cancer
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
ultrasound-guided thermal ablation
Procedure/Surgerymicrowave ablation, radiofrequency ablation, laser ablation
Treatment groups
300 Participants
are divided into 1 treatment groupGroup A: ultrasound-guided thermal ablation1 intervention
Trial outcomes
Primary outcomes
1
rate of disease progression
cervical lymph node metastases and persistent tumors confirmed by pathology, Distant metastasis detected by CT, positron emission tomography, or bone scan if there were suspicious symptoms.
Time frame
through study completion, an average of 6 monthsSecondary outcomes
1
rate of complications
complication of ablation
Time frame
1 week2
rate of volume reduction
volume reduction of tumor after ablation on ultrasound and contrast-enhanced ultrasound
Time frame
through study completion, an average of 6 months3
rate of tumor disappearance
complete disappearance of ablated tumor on ultrasound and contrast-enhanced ultrasound
Time frame
through study completion, an average of 6 months4
Tg level
serum thyroglobulin level
Time frame
through study completion, an average of 6 monthsSponsors and contacts
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Source ClinicalTrials.gov