[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100494200":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":23,"centralContacts":27,"locations":36,"responsibleParty":55,"collaborators":57,"id":62,"slug":11,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":70,"minAge":71,"maxAge":11,"enrollmentInfo":72,"targetDuration":11,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":38,"whyStopped":11,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A (Upfront ureteroscopy)","ACTIVE_COMPARATOR",null,[13],"Procedure: Ureteroscopy",{"label":15,"type":16,"description":11,"interventionNames":11},"Group B (Observation\u002Fdelayed ureteroscopy)","NO_INTERVENTION",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"PROCEDURE","Ureteroscopy","Upfront ureteroscopy",[9],[24],{"name":25,"affiliation":5,"role":26},"Thomas Chi, MD","PRINCIPAL_INVESTIGATOR",[28,33],{"name":29,"role":30,"phone":31,"phoneExt":11,"email":32},"Catherine Arevalo, BA","CONTACT","415-514-0918","catherine.arevalo@ucsf.edu",{"name":34,"role":30,"phone":11,"phoneExt":11,"email":35},"Heiko Yang, MD","heiko.yang@ucsf.edu",[37],{"facility":5,"status":38,"city":39,"state":40,"zip":41,"country":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","San Francisco","California","94143","United States",{"type":44,"coordinates":45},"Point",[46,47],-122.41942,37.77493,{"lat":47,"lon":46},[50,53],{"name":51,"role":30,"phone":11,"phoneExt":11,"email":52},"Tom Chi, MD","tom.chi@ucsf.edu",{"name":34,"role":30,"phone":54,"phoneExt":11,"email":35},"513-8862172",{"type":56,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR",[58,60],{"name":59,"class":6},"University of Colorado, Denver",{"name":61,"class":6},"State University of New York - Upstate Medical University","100494200",false,"NCT05715086","UPURS Trial for Patient-centered Management of Symptomatic Obstructing Stones","Upfront vs Postponed Ureteroscopy (UPURS) Trial for Patient-centered Management of Symptomatic Obstructing Stones","UPURS","Inclusion Criteria:\n\n* Presenting to the Emergency Department (ED)\n* Adult (\\> 18 yo)\n* ≥5mm ureteral stone diagnosed on CT scan\n* Presence of symptoms (pain, nausea, vomiting, hematuria)\n\nExclusion Criteria:\n\n* Strict indication for stent\n* Stone burden not amenable to Ureteroscopy (URS)\n* Dirty urine analysis (UA) or positive urine culture (UCx)\n* Transplant kidney\n* Presence of conduit\n* Comorbidities not optimized for surgery\n* Strong preference for surgery or observation",true,"ALL","18 Years",{"count":73,"type":74},100,"ESTIMATED","INTERVENTIONAL",[77],"NA","A prospective, non-blinded, randomized controlled trial studying the management of symptomatic ureteral stones. This study will compare upfront ureteroscopy vs observation and delayed intervention for patients presenting to the emergency department with a symptomatic ureteral stone.",[80],"Ureteral Stone",[82],"Symptomatic ureteral stones","2025-01-15",{"date":85,"type":86},"2025-01-17","ACTUAL",{"date":88,"type":86},"2023-08-23",{"date":90,"type":74},"2026-06-30",{"name":5,"class":6},1]