[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100464247":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":52,"collaborators":54,"id":57,"slug":26,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":26,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":26,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":79,"overallStatus":81,"whyStopped":26,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"POPRC group","EXPERIMENTAL","pelvic-organ preserving radical cystectomy with orthotopic ileal neobladder",[13],"Procedure: POPRC+OIN",{"label":15,"type":16,"description":17,"interventionNames":18},"SRC group","ACTIVE_COMPARATOR","standard radical cystectomy with orthotopic ileal neobladder",[19],"Procedure: SRC+OIN",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","POPRC+OIN","Pelvic-organ preserving radical cystectomy with orthotopic ileal neobladder",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"SRC+OIN","Standard radical cystectomy with orthotopic ileal neobladder",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Wenlong Zhong, MD","CONTACT","86-18510904167","zhongwlong3@mail.sysu.edu.cn",[38],{"facility":39,"status":26,"city":40,"state":41,"zip":26,"country":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Sun Yat-Sen Memorial Hospital","Guangzhou","Guangdong","China",{"type":44,"coordinates":45},"Point",[46,47],113.25,23.11667,{"lat":47,"lon":46},[50],{"name":51,"role":34,"phone":35,"phoneExt":26,"email":36},"Wenlong Zhong",{"type":53,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[55],{"name":56,"class":6},"Peking University Third Hospital","100464247",false,"NCT05325216","Urinary Continence of Female POPRC and OIN","Urinary Continence of Female Pelvic Organ-preserving Radical Cystectomy and Orthotopic Ileal Neobladder: A Randomized Controlled Study","Inclusion Criteria:\n\n1. Female patients aged between 55-75.\n2. Patients those who are diagnosed with organ-confined urothelial carcinoma（\\\u003CpT3）\n3. Patients those who are capable for radical cystectomy with orthotopic ileal neobladder.\n4. ECOG score between 0-2;\n5. Normal renal function;\n6. Patients those who volunteer to participate in this study and sign the informed consents.\n7. Patients those who are able to cooperate in the study.\n\nExclusion Criteria:\n\n1. Absence of tumour in bladder neck or urethra;\n2. Patients thsoe who are diagnosed distant metastasis before surgery.\n3. Previous history of malignancy of pelvic organs or surgical resection of pelvic organs;\n4. Patients those who are diagnosed with other malignancies.;\n5. Patients those who had received pelvic radiotherapy or major pelvic operation.\n6. Pregnancy status;\n7. Any other conditions that the researcher considers to be excluded from this study","FEMALE","55 Years","75 Years",{"count":67,"type":68},58,"ESTIMATED","INTERVENTIONAL",[71],"NA","To compare the urinary continence rate and long-term oncological outcomes of pelvic-organ preserving radical cystectomy (POPRC) with orthotopic ileal neobladder (OIN) versus standard radical cystectomy(SRC) with OIN.",[74,75,76,77,78],"Urinary Bladder Neoplasms","Woman","Sexual Dysfunction, Physiological","Treatment Outcome","Urinary Incontinence",[80],"Bladder cancer, Female, Pelvic organ preserving-radical cystectomy, Radical cystectomy, Orthotopic ileal neobladder","NOT_YET_RECRUITING","2022-04-12",{"date":84,"type":85},"2022-04-13","ACTUAL",{"date":87,"type":68},"2022-04",{"date":89,"type":68},"2028-04-01",{"name":5,"class":6},1]