About this trial

UPRIGHT-HTM will compare risk stratification, treatment efficiency and health economic outcomes of a diagnostic approach based on home blood pressure telemonitoring combined with urinary proteomic profiling with home blood pressure telemonitoring alone

Eligibility criteria

Qualifiers

Patients must have at least three additional guideline-defined risk factors, preferably including hypertension, type 2 diabetes mellitus (T2DM), or both;

Patients should be willing patients to engage for the duration of the study in home blood pressure telemonitoring (1 reading per day);

Patients must have an email address and internet access via smartphone, tablet, or laptop or desktop computer;

Patients should comply with the study protocol during the run-in phase.

Disqualifiers

Type 1 diabetes mellitus;

Absence of a practicable echocardiographic window;

Previous or concurrent severe cardiovascular or non-cardiovascular disease;

Cancer within 5 years of enrolment;

Trial design

Treatments tested in this trial

  • In-vitro urinary diagnostic test

Treatment groups

1,000 Participants
are divided into 2 treatment groups

Locations

12
Belgium
European Kidney Health Aliance1000, Brussels Belgium
Diabetes Liga9000, Ghent Belgium
Alliance for the Promotion of Preventive Medicine2800, Mechelen Belgium
Denmark
Steno Diabetes Center Copenhagen2820, Gentofte Municipality Denmark

Sponsors and collaborators

KU Leuven

Lead sponsor

Alliance for the Promotion of Preventive Medicine

Collaborator