[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621423":3},{"organization":4,"outcomesModule":7,"designInfo":37,"detailedDescription":46,"studyPopulation":36,"armGroups":47,"interventions":57,"overallOfficials":36,"centralContacts":63,"locations":73,"responsibleParty":88,"collaborators":36,"id":92,"slug":36,"hasResults":93,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":97,"eligibilityCriteria":98,"healthyVolunteers":93,"sex":99,"minAge":100,"maxAge":101,"enrollmentInfo":102,"targetDuration":36,"studyType":105,"phases":106,"briefSummary":108,"conditions":109,"keywords":111,"overallStatus":75,"whyStopped":36,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},{"fullName":5,"class":6},"Bursa City Hospital","OTHER_GOV",{"primaryOutcomes":8,"secondaryOutcomes":17,"otherOutcomes":36},[9,13],{"measure":10,"description":11,"timeFrame":12},"Postoperative 48-Hour PCA Opioid Consumption","Total amount of opioid delivered by the patient-controlled analgesia (PCA) device during the first 48 hours after surgery, recorded in milligrams (mg).","Postoperative 0-8, 8-16, 16-24, 24-48 intervals",{"measure":14,"description":15,"timeFrame":16},"QoR-15 Recovery Score","The investigators will use the Turkish version of Quality of Recovery (QoR) \u002F QoR-15 questionairre\n\nPART A How have you been feeling in the last 24 hours? (0 to 10, where: 0 = none of the time \\[poor\\] and 10 = all of the time \\[excellent\\])\n\nAble to breathe easily Been able to enjoy food Feeling rested Have had a good sleep Able to look after personal toilet and hygiene unaided Able to communicate with Getting support from hospital doctors and nurses Able to return to work or usual home activities Feeling comfortable and in control Having a feeling of general well-being\n\nPART B Have you had any of the following in the last 24 hours? (10 to 0, where: 10 = none of the time \\[excellent\\] and 0 = all of the time \\[poor\\]) Moderate pain Severe pain Nausea or vomiting Feeling worried or anxious Feeling sad or depressed","Postoperative 24th and 48th hours",[18,22,25,29,33],{"measure":19,"description":20,"timeFrame":21},"Dynamic and static NRS scores","Numeric Rating Scale (NRS) (0-10) pain scores at rest or movement at predefined postoperative hours","0, 2, 4, 8, 16, 24, and 48 hours postoperatively",{"measure":23,"description":24,"timeFrame":16},"Total rescue analgesic dose","Despite the use of patient-controlled analgesia (PCA), if the Numeric Rating Scale (NRS) score is ≥4 at any time point, 0.5 mg\u002Fkg intravenous meperidine will be administered as rescue analgesia.\n\nTotal amount of meperidin during the first 24 and 48 hours after surgery, recorded in milligrams (mg).",{"measure":26,"description":27,"timeFrame":28},"Time of first request for rescue analgesia","Despite the use of patient-controlled analgesia (PCA), if the Numeric Rating Scale (NRS) score is ≥4 at any time point, 0.5 mg\u002Fkg intravenous meperidine will be administered as rescue analgesia.","Postoperative 48-Hours",{"measure":30,"description":31,"timeFrame":32},"Length of Hospital Stay","Length of hospital stay will be defined as the number of days from the end of surgery to hospital discharge.","Patients will remain under observation for at least 2 weeks until their postoperative discharge. Follow-up will be completed upon discharge. The length of hospital stay will be recorded (day).",{"measure":34,"description":35,"timeFrame":28},"Block and Opioid-Related Adverse Effects and Complications","Block- and opioid-related adverse effects and complications, including but not limited to local anesthetic toxicity, hematoma, infection, nerve injury, nausea, vomiting, pruritus, sedation, and respiratory depression, will be recorded",null,{"allocation":38,"interventionModel":39,"interventionModelDescription":36,"primaryPurpose":40,"observationalModel":36,"timePerspective":36,"maskingInfo":41},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":42,"maskingDescription":36,"whoMasked":43},"DOUBLE",[44,45],"INVESTIGATOR","OUTCOMES_ASSESSOR","Lumbar instrumentation surgery is associated with significant postoperative pain, which may reduce patient comfort, delay early mobilization, and increase analgesic requirements. Effective postoperative pain management is essential for enhancing recovery and reducing postoperative morbidity. In this context, regional anesthesia techniques have become an important component of multimodal analgesia strategies.\n\nThe Quadro-Iliac Plane Block is a newly described ultrasound-guided regional analgesia technique. This block aims to provide effective analgesia by targeting the relevant branches of the lumbar nerves supplying the surgical area. However, clinical evidence regarding its effectiveness in postoperative analgesia following lumbar instrumentation surgery remains limited.\n\nThis study aims to evaluate the postoperative analgesic effectiveness of the ultrasound-guided Quadro-Iliac Plane Block in patients undergoing lumbar instrumentation surgery. The findings of this study are expected to contribute to the assessment of this newly developed technique as a safe and effective option for postoperative pain management in lumbar spine surgery.",[48,54],{"label":49,"type":50,"description":51,"interventionNames":52},"Group QIPB","ACTIVE_COMPARATOR","Participants in this arm will receive an ultrasound-guided Quadro-Iliac Plane Block. The block will be performed at the end of surgery, before extubation, with the patient in the prone position under standard sterilization conditions. A convex ultrasound probe will be placed at the level where the quadratus lumborum muscle (QLM) attaches to the iliac crest to visualize the erector spinae muscle (ESM) and the underlying QLM.\n\nThe block location will be confirmed by injecting 2 mL of isotonic solution at the QLM-iliac crest junction. Subsequently, 20 mL of 0.25% bupivacaine will be injected, and the spread of the local anesthetic between the ESM and QLM will be observed under ultrasound guidance. The block will be performed bilaterally with a total volume of 40 mL.",[53],"Procedure: Quadro-Iliac Plane Block",{"label":55,"type":56,"description":36,"interventionNames":36},"Group Control","NO_INTERVENTION",[58],{"type":59,"name":60,"description":61,"armGroupLabels":62,"otherNames":36},"PROCEDURE","Quadro-Iliac Plane Block","Ultrasound-guided regional anesthesia technique performed between the erector spinae muscle and the quadratus lumborum muscle at the iliac crest level.",[49],[64,69],{"name":65,"role":66,"phone":67,"phoneExt":36,"email":68},"Mursel Ekinci, Assoc prof,MD","CONTACT","+905067137596","drmurselekinci@gmail.com",{"name":70,"role":66,"phone":71,"phoneExt":36,"email":72},"Merih Yıldız Eglen, MD","+905059340629","meriheg@yahoo.com",[74],{"facility":5,"status":75,"city":76,"state":36,"zip":77,"country":78,"countryCode":36,"cosmosGeoPoint":79,"geoPoint":84,"contacts":85},"RECRUITING","Bursa","16110","Turkey (Türkiye)",{"type":80,"coordinates":81},"Point",[82,83],29.06013,40.19559,{"lat":83,"lon":82},[86],{"name":87,"role":66,"phone":71,"phoneExt":36,"email":72},"Merih Yildiz Eglen, MD",{"type":89,"investigatorFullName":90,"investigatorTitle":91,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"PRINCIPAL_INVESTIGATOR","Merih Yıldız Eglen","Principal Investigator, MD","100621423",false,"NCT07370428","US-Guided Quadro-Iliac Plane Block for Postoperative Analgesia After Lumbar Instrumentation","Evaluation of the Effectiveness of Ultrasound-Guided Quadro-Iliac Plane Block in Postoperative Analgesia Management Following Lumbar Instrumentation Surgery","QIPB","Inclusion Criteria:\n\n* Classified as American Society of Anesthesiologists (ASA) physical status I-III\n* Scheduled for elective lumbar instrumentation surgery\n* Surgery performed under general anesthesia\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Use of anticoagulant or antiplatelet medications\n* Presence of bleeding diathesis or coagulation disorders\n* Known allergy or hypersensitivity to local anesthetics or opioid medications\n* Infection at the planned block site\n* Alcohol or drug dependence\n* Cognitive impairment preventing reliable pain assessment using the NRS\n* Pregnancy or lactation\n* History of previous lumbar spine surgery\n* Diabetes mellitus\n* Renal or hepatic impairment","ALL","18 Years","65 Years",{"count":103,"type":104},80,"ESTIMATED","INTERVENTIONAL",[107],"NA","Lumbar instrumentation surgery is associated with significant postoperative pain. This study evaluates the analgesic effectiveness of the ultrasound-guided Quadro-Iliac Plane Block in patients undergoing lumbar instrumentation surgery, aiming to assess the efficacy of this newly developed technique for postoperative pain management.",[110],"Postoperative Pain",[60,112,113],"Lumbar Instrumentation Surgery","Pain Management","2026-03-05",{"date":116,"type":117},"2026-03-06","ACTUAL",{"date":119,"type":117},"2026-01-20",{"date":121,"type":104},"2026-07-01",{"name":5,"class":6},1]