[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639913":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":20,"studyPopulation":13,"armGroups":21,"interventions":28,"overallOfficials":13,"centralContacts":34,"locations":13,"responsibleParty":40,"collaborators":13,"id":44,"slug":13,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":45,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":13,"studyType":56,"phases":57,"briefSummary":58,"conditions":59,"keywords":13,"overallStatus":61,"whyStopped":13,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":13},{"fullName":5,"class":6},"Cardarelli Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Testosterone levels","Variation of serum testosterone levels","From enrollment to three months",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":13,"primaryPurpose":17,"observationalModel":13,"timePerspective":13,"maskingInfo":18},"NA","SINGLE_GROUP","TREATMENT",{"masking":19,"maskingDescription":13,"whoMasked":13},"NONE","The study involves the recruitment of 35 functional hypogonadal patients aged between 50 and 75 years to the Andrology Unit of the \"Antonio Cardarelli\" Hospital. At T0 patients will undergo hematochemical evaluation of the following parameters: total and free testosterone, PSA and hematocrit.\n\nAt the same time, they will be provided with a self-assessment questionnaire on physical and sexual functioning. The same evaluations will be performed after 3 months of supplementation (T1).\n\nThe main endpoint is the intra-subject variation in total and free testosterone levels between T0 and T1.",[22],{"label":23,"type":24,"description":25,"interventionNames":26},"Treated","EXPERIMENTAL","Treatment with D-chiro-inositol",[27],"Dietary Supplement: D-chiro-inositol",[29],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":13},"DIETARY_SUPPLEMENT","D-chiro-inositol","Treatment with D-chiro-inositol (capsule) for 3 months 600 mg\u002F2 die",[23],[35],{"name":36,"role":37,"phone":38,"phoneExt":13,"email":39},"Maurizio Carrino, MD","CONTACT","+39 081 7472474","maurizio.carrino@aocardarelli.it",{"type":41,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"PRINCIPAL_INVESTIGATOR","Maurizio Carrino","Dr","100639913",false,"NCT07584772","Use of D-Chiro-inositol in Male Functional Hypogonadism Associated With Sexual Dysfunction","HERO_2025","Inclusion Criteria:\n\n* Men aged between 50 and 75\n* Affected by functional hypogonadism associated with male aging\n\nExclusion Criteria:\n\n* Elevated ferritin, PRL, and\u002For elevated CRP values; diagnosis of primary hypogonadism; diagnosis of organic hypogonadotropic hypogonadism or secondary to other ongoing acute or chronic pathologies; presence of other pituitary deficits.\n* Alcohol use and\u002For drug abuse, recent hormone treatment, smoking, systemic or endocrine diseases, infection of the male accessory glands, medical history of cryptorchidism or varicocele, and micro-orchidism.","MALE","50 Years","75 Years",{"count":54,"type":55},35,"ESTIMATED","INTERVENTIONAL",[15],"A prospective, uncontrolled, non-pharmacological interventional study conducted on men with functional or borderline hypogonadism, aimed at evaluating, after 3 months of supplementation with D-Chiro-inositol, changes in hormonal profile and sexual function.",[60],"Functional Hypogonadism","NOT_YET_RECRUITING","2026-05-07",{"date":64,"type":65},"2026-05-13","ACTUAL",{"date":67,"type":55},"2026-07-01",{"date":69,"type":55},"2027-01-01",{"name":5,"class":6}]