[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644357":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":13,"studyPopulation":17,"armGroups":13,"interventions":13,"overallOfficials":13,"centralContacts":18,"locations":24,"responsibleParty":40,"collaborators":13,"id":42,"slug":13,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":43,"sex":48,"minAge":49,"maxAge":13,"enrollmentInfo":50,"targetDuration":13,"studyType":53,"phases":13,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":27,"whyStopped":13,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":68},{"fullName":5,"class":6},"Centre Hospitalier Universitaire de Besancon","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Number of participants with response to extracorporeal photopheresis (ECP) at 1 year","Response is defined as either:\n\n* stable serum creatinine at 1 year after initiation of ECP, corresponding to a variation within ±20% of baseline serum creatinine (responder); or\n* a reduction in the slope of creatinine clearance decline following initiation of ECP compared with the pre-treatment trajectory (partial responder).\n\nParticipants meeting either criterion are considered responders for the primary efficacy analysis.","One year after initiation of ECP",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":16,"maskingInfo":13},"COHORT","RETROSPECTIVE","Kidney transplant recipients presenting with antibody-mediated rejection and treated with extracorporeal photopheresis",[19],{"name":20,"role":21,"phone":22,"phoneExt":13,"email":23},"Charline Vauchy, PhD.","CONTACT","+33381218875","cvauchy@chu-besancon.fr",[25],{"facility":26,"status":27,"city":28,"state":13,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Centre Hospitalier Universitaire de Besançon","RECRUITING","Besançon","25000","France","FR",{"type":33,"coordinates":34},"Point",[35,36],6.01815,47.24878,{"lat":36,"lon":35},[39],{"name":20,"role":21,"phone":22,"phoneExt":13,"email":23},{"type":41,"investigatorFullName":13,"investigatorTitle":13,"investigatorAffiliation":13,"oldNameTitle":13,"oldOrganization":13},"SPONSOR","100644357",false,"NCT07663669","Use of Extracorporeal Photopheresis in Kidney Transplantation: Effects on Antibody-Mediated Rejection","PETRUM","Inclusion Criteria:\n\n* Kidney transplant recipients followed at the University Hospitals of Besançon and Lille between September 1, 2016, and August 31, 2023\n* Patients with antibody-mediated rejection (as confirmed by histological analysis of the renal biopsy)\n* Rejection treated with extracorporeal photopheresis\n* Subjects who do not object to the use of their personal data and\u002For biological samples\n* Subjects affiliated with, or beneficiaries of, the French social security system\n\nExclusion Criteria:\n\n* Patients with acute rejection\n* Pregnant women, women in labor, or breastfeeding mothers\n* Individuals deprived of liberty by judicial or administrative decision; individuals receiving compulsory psychiatric care; or individuals admitted to a healthcare or social institution for reasons other than research participation\n* Minors\n* Adults under legal protection or unable to provide informed consent\n* Subjects without health insurance coverage\n* Subjects currently within an exclusion period from another study, or as listed in the \"national volunteer registry\"","ALL","18 Years",{"count":51,"type":52},31,"ESTIMATED","OBSERVATIONAL","This study aims to describe, over a one-year period, the clinical, biological, and histological evolution of a cohort of kidney transplant recipients who developed antibody-mediated rejection and were treated with extracorporeal photopheresis.",[56],"Antibody-mediated Rejection in Kidney Transplant",[58],"Extracorporeal photopheresis","2026-06-24",{"date":61,"type":62},"2026-06-29","ACTUAL",{"date":64,"type":52},"2026-06",{"date":66,"type":52},"2026-10",{"name":5,"class":6},1]