Using a Hypotension Prediction Index to Prevent Low Blood Pressure During Dialysis in ICU Patients
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorChulalongkorn University
About this trial
This single-center, crossover randomized controlled trial (HyPIR-ICU) investigates whether a Hypotension Prediction Index (HPI)-guided management strategy can reduce intradialytic hypotension (IDH) during prolonged intermittent renal replacement therapy (PIRRT) in critically ill patients. All participants must have an indwelling arterial catheter for continuous hemodynamic monitoring.
Eligibility criteria
Qualifiers
Adults >18 years old
Diagnosed with acute kidney injury (AKI) or end-stage kidney disease (ESKD)
Admitted to medical ICU
Scheduled for PIRRT
Disqualifiers
Severe right heart dysfunction, significant valvular disease, arrhythmias, mechanical circulatory support, absence of arterial access, no UF prescription, palliative care, or expected ICU stay <72 hours.
Trial design
Treatments tested in this trial
- Hypotensive prediction index
- Standard of care monitoring
Treatment groups
46 Participants
are divided into 2 treatment groupsLocations
1Division of Nephrology, Faculty of Medicine, Chulalongkorn University Bangkok Thailand
Sponsors and collaborators
Chulalongkorn University
Lead sponsor
Source ClinicalTrials.gov