Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorH. Lee Moffitt Cancer Center and Research Institute

About this trial

The Florida Pancreas Collaborative wants to partner with individuals who are known to have, or are suspected to have a pancreatic lesion, tumor, cyst, mass, cancer, or pancreatitis and are undergoing diagnosis and treatment at a participating institution. The goals of this project are to build a large database of information obtained from blood, tissue, medical images, surveys and information from routine care to develop noninvasive diagnostic approaches that could be used as decision-making tools to effectively personalize clinical care.

Eligibility criteria

Qualifiers

Individuals who present to the GI clinic, surgery, or endoscopy at Moffitt, Florida Research Institute (FRI), or UM with a clinical suspicion for (or diagnosis of) a pancreatic lesion, cyst, mass, cancer, or pancreatitis based on symptoms, imaging, or blood-work and has not had any treatment involving their pancreas.

Able to understand and voluntarily sign the informed consent.

Willing to complete study questionnaire(s) and donate medical images and/or biological specimens (including blood, cystic fluid, and/or tissue) obtained at the time of standard of care procedures (biopsy, surgery, and venipuncture) after signing the informed consent document

Disqualifiers

No suspicion or diagnosis of a pancreatic lesion, cyst, mass, cancer, or pancreatitis.

Has a diagnosis of a pancreatic lesion, cyst, mass, cancer, or pancreatitis and has already undergone treatment involving the pancreas (which may involve surgery, chemo- or immuno-therapy, and/or radiation).

Unable to provide informed consent.

Unwilling to complete study questionnaire(s) and/or donate biological specimens or images.

Trial design

Treatments tested in this trial

  • Blood Sample collection
  • Tissue sample collection
  • Data collection

Treatment groups

1,174 Participants
are divided into 2 treatment groups

Locations

3
Florida Research Institute (FRI)34211, Lakewood RchFlorida, United States
Sylvester Comprehensive Cancer Center & Jackson Memorial Hospital33136, MiamiFlorida, United States
Moffitt Cancer Center33612, TampaFlorida, United States

Sponsors and collaborators

H. Lee Moffitt Cancer Center and Research Institute

Lead sponsor

National Cancer Institute (NCI)

Collaborator

University of Florida

Collaborator

University of Miami

Collaborator