[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100506479":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":32,"locations":38,"responsibleParty":337,"collaborators":10,"id":339,"slug":10,"hasResults":340,"nctId":341,"briefTitle":342,"officialTitle":343,"acronym":344,"eligibilityCriteria":345,"healthyVolunteers":340,"sex":346,"minAge":347,"maxAge":10,"enrollmentInfo":348,"targetDuration":351,"studyType":352,"phases":10,"briefSummary":353,"conditions":354,"keywords":363,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":389,"lastUpdatePostDateStruct":390,"startDateStruct":393,"completionDateStruct":395,"leadSponsor":397,"locationsCount":398},{"fullName":5,"class":6},"UroGen Pharma Ltd.","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Jelmyto",null,"Patients with UTUC treated with Jelmyto",[13],"Drug: Jelmyto (mitomycin) for pyelocalyceal solution",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","Jelmyto (mitomycin) for pyelocalyceal solution","The dose of Jelmyto to be instilled is 4 mg per mL via ureteral catheter or a nephrostomy tube, with total instillation volume based on volumetric measurements using pyelography, not to exceed 15 mL (60 mg of mitomycin).\n\nInstill Jelmyto once weekly for six weeks. For patients with a complete response 3 months after Jelmyto initiation, Jelmyto instillations may be administered once a month for a maximum of 11 additional instillations.",[9],[9,21],"UGN-101",[23,27,30],{"name":24,"affiliation":25,"role":26},"Yair Lotan, MD","UT Southwestern Medical Center at Dallas","PRINCIPAL_INVESTIGATOR",{"name":28,"affiliation":29,"role":26},"Adam Feldman, MD","Massachusett's General Hospital",{"name":31,"affiliation":25,"role":26},"Solomon Woldu, MD",[33],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},"Michael Louie, MD, MPH, MSc","CONTACT","855-987-6436","registry@urogen.com",[39,56,71,84,97,111,125,139,153,163,176,186,200,214,228,242,254,267,281,296,310,324],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Providence St. Johns Health Center","RECRUITING","Santa Monica","California","90404","United States",{"type":47,"coordinates":48},"Point",[49,50],-118.49138,34.01949,{"lat":50,"lon":49},[53],{"name":54,"role":35,"phone":10,"phoneExt":10,"email":55},"Jennifer Linehan, MD","Jennifer.linehan@providence.org",{"facility":57,"status":41,"city":58,"state":59,"zip":60,"country":45,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"University of Florida","Gainesville","Florida","32610",{"type":47,"coordinates":62},[63,64],-82.32483,29.65163,{"lat":64,"lon":63},[67],{"name":68,"role":35,"phone":69,"phoneExt":10,"email":70},"Padraic OMalley, MD","352-265-8240","Padraic.O'Malley@urology.ufl.edu",{"facility":72,"status":41,"city":73,"state":59,"zip":74,"country":45,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"Mount Sinai Medical Center of Florida, Inc.","Miami","33140",{"type":47,"coordinates":76},[77,78],-80.19366,25.77427,{"lat":78,"lon":77},[81],{"name":82,"role":35,"phone":10,"phoneExt":10,"email":83},"Alan Nieder, MD","Alan.Nieder@msmc.com",{"facility":85,"status":41,"city":86,"state":59,"zip":87,"country":45,"cosmosGeoPoint":88,"geoPoint":92,"contacts":93},"H. Lee Moffitt Cancer Center and Research Institute Hospital, Inc.","Tampa","33612",{"type":47,"coordinates":89},[90,91],-82.45843,27.94752,{"lat":91,"lon":90},[94],{"name":95,"role":35,"phone":10,"phoneExt":10,"email":96},"Wade Sexton, MD","Wade.Sexton@moffitt.org",{"facility":98,"status":41,"city":99,"state":100,"zip":101,"country":45,"cosmosGeoPoint":102,"geoPoint":106,"contacts":107},"Northwestern University","Chicago","Illinois","60611",{"type":47,"coordinates":103},[104,105],-87.65005,41.85003,{"lat":105,"lon":104},[108],{"name":109,"role":35,"phone":10,"phoneExt":10,"email":110},"Joshua Meeks, MD","joshua.meeks@northwestern.edu",{"facility":112,"status":41,"city":113,"state":114,"zip":115,"country":45,"cosmosGeoPoint":116,"geoPoint":120,"contacts":121},"Indiana University","Indianapolis","Indiana","46202",{"type":47,"coordinates":117},[118,119],-86.15804,39.76838,{"lat":119,"lon":118},[122],{"name":123,"role":35,"phone":10,"phoneExt":10,"email":124},"Hristos Kaimakliotis, MD","hkaimakl@iupui.edu",{"facility":126,"status":41,"city":127,"state":128,"zip":129,"country":45,"cosmosGeoPoint":130,"geoPoint":134,"contacts":135},"The State University of Iowa","Iowa City","Iowa","52242",{"type":47,"coordinates":131},[132,133],-91.53017,41.66113,{"lat":133,"lon":132},[136],{"name":137,"role":35,"phone":10,"phoneExt":10,"email":138},"Michael ODonnell, MD","michael-odonnell@uiowa.edu",{"facility":140,"status":41,"city":141,"state":142,"zip":143,"country":45,"cosmosGeoPoint":144,"geoPoint":148,"contacts":149},"Chesapeake Urology","Baltimore","Maryland","21204",{"type":47,"coordinates":145},[146,147],-76.61219,39.29038,{"lat":147,"lon":146},[150],{"name":151,"role":35,"phone":10,"phoneExt":10,"email":152},"Rian Dickstein, MD","rdickstein@chesuro.com",{"facility":154,"status":41,"city":141,"state":142,"zip":155,"country":45,"cosmosGeoPoint":156,"geoPoint":158,"contacts":159},"Johns Hopkins Medical Center","21287",{"type":47,"coordinates":157},[146,147],{"lat":147,"lon":146},[160],{"name":161,"role":35,"phone":162,"phoneExt":10,"email":10},"Nirmish Singla, MD","410-955-6100",{"facility":164,"status":41,"city":165,"state":166,"zip":167,"country":45,"cosmosGeoPoint":168,"geoPoint":172,"contacts":173},"Mass General Hospital (MGH)","Boston","Massachusetts","02114",{"type":47,"coordinates":169},[170,171],-71.05977,42.35843,{"lat":171,"lon":170},[174],{"name":28,"role":35,"phone":10,"phoneExt":10,"email":175},"afeldman@mgb.org",{"facility":177,"status":41,"city":165,"state":166,"zip":178,"country":45,"cosmosGeoPoint":179,"geoPoint":181,"contacts":182},"The Brigham and Womens Hospital","02115",{"type":47,"coordinates":180},[170,171],{"lat":171,"lon":170},[183],{"name":184,"role":35,"phone":10,"phoneExt":10,"email":185},"Steven Chang, MD","SLCHANG@BWH.HARVARD.EDU",{"facility":187,"status":41,"city":188,"state":189,"zip":190,"country":45,"cosmosGeoPoint":191,"geoPoint":195,"contacts":196},"University of Michigan","Ann Arbor","Michigan","48109",{"type":47,"coordinates":192},[193,194],-83.74088,42.27756,{"lat":194,"lon":193},[197],{"name":198,"role":35,"phone":10,"phoneExt":10,"email":199},"Khurshid Ghani, MD","kghani@med.umich.edu",{"facility":201,"status":41,"city":202,"state":203,"zip":204,"country":45,"cosmosGeoPoint":205,"geoPoint":209,"contacts":210},"University of Missouri","Columbia","Missouri","65211",{"type":47,"coordinates":206},[207,208],-92.33407,38.95171,{"lat":208,"lon":207},[211],{"name":212,"role":35,"phone":10,"phoneExt":10,"email":213},"Eliza DeFroda, MD","elddmc@health.missouri.edu",{"facility":215,"status":41,"city":216,"state":217,"zip":218,"country":45,"cosmosGeoPoint":219,"geoPoint":223,"contacts":224},"Rutgers","New Brunswick","New Jersey","08903",{"type":47,"coordinates":220},[221,222],-74.45182,40.48622,{"lat":222,"lon":221},[225],{"name":226,"role":35,"phone":10,"phoneExt":10,"email":227},"Saum Ghodoussipour, MD","sg1621@cinj.rutgers.edu",{"facility":229,"status":41,"city":230,"state":231,"zip":232,"country":45,"cosmosGeoPoint":233,"geoPoint":237,"contacts":238},"The Feinstein Institutes for Medical Research","Lake Success","New York","11042",{"type":47,"coordinates":234},[235,236],-73.71763,40.77066,{"lat":236,"lon":235},[239],{"name":240,"role":35,"phone":10,"phoneExt":10,"email":241},"David Hoenig, MD","dhoenig@northwell.edu",{"facility":243,"status":41,"city":231,"state":231,"zip":244,"country":45,"cosmosGeoPoint":245,"geoPoint":249,"contacts":250},"NYU Grossman School of Medicine","10016",{"type":47,"coordinates":246},[247,248],-74.00597,40.71427,{"lat":248,"lon":247},[251],{"name":252,"role":35,"phone":10,"phoneExt":10,"email":253},"Katie Murray, MD","Katie.Murray@nyulangone.org",{"facility":255,"status":41,"city":256,"state":231,"zip":257,"country":45,"cosmosGeoPoint":258,"geoPoint":262,"contacts":263},"SUNY Upstate","Syracuse","13210",{"type":47,"coordinates":259},[260,261],-76.14742,43.04812,{"lat":261,"lon":260},[264],{"name":265,"role":35,"phone":10,"phoneExt":10,"email":266},"Joseph Jacob, MD","JacobJ@upstate.edu",{"facility":268,"status":41,"city":269,"state":270,"zip":271,"country":45,"cosmosGeoPoint":272,"geoPoint":276,"contacts":277},"The University of North Carolina Chapel Hill","Chapel Hill","North Carolina","27599",{"type":47,"coordinates":273},[274,275],-79.05584,35.9132,{"lat":275,"lon":274},[278],{"name":279,"role":35,"phone":10,"phoneExt":10,"email":280},"Marc Bjurlin, MD","marc_bjurlin@med.unc.edu",{"facility":282,"status":41,"city":283,"state":284,"zip":285,"country":45,"cosmosGeoPoint":286,"geoPoint":290,"contacts":291},"Ohio State University","Columbus","Ohio","43202",{"type":47,"coordinates":287},[288,289],-82.99879,39.96118,{"lat":289,"lon":288},[292],{"name":293,"role":35,"phone":294,"phoneExt":10,"email":295},"Ahmad Shabsigh, MD","614-685-4263","Ahmad.Shabsigh@osumc.edu",{"facility":297,"status":41,"city":298,"state":299,"zip":300,"country":45,"cosmosGeoPoint":301,"geoPoint":305,"contacts":306},"Medical University of South Carolina","Charleston","South Carolina","29425",{"type":47,"coordinates":302},[303,304],-79.93275,32.77632,{"lat":304,"lon":303},[307],{"name":308,"role":35,"phone":10,"phoneExt":10,"email":309},"Karthik Tanneru, MD","tanneru@musc.edu",{"facility":311,"status":41,"city":312,"state":313,"zip":314,"country":45,"cosmosGeoPoint":315,"geoPoint":319,"contacts":320},"UT Southwestern Medical Center","Dallas","Texas","75390",{"type":47,"coordinates":316},[317,318],-96.80667,32.78306,{"lat":318,"lon":317},[321],{"name":322,"role":35,"phone":10,"phoneExt":10,"email":323},"Brett Johnson, MD","Brett.Johnson@UTSouthwestern.edu",{"facility":325,"status":41,"city":326,"state":313,"zip":327,"country":45,"cosmosGeoPoint":328,"geoPoint":332,"contacts":333},"The University of Texas M.D. Anderson Cancer Center","Houston","77030",{"type":47,"coordinates":329},[330,331],-95.36327,29.76328,{"lat":331,"lon":330},[334],{"name":335,"role":35,"phone":10,"phoneExt":10,"email":336},"Mehrad Adibi, MD","MAdibi@mdanderson.org",{"type":338,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100506479",false,"NCT05874921","uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto","uTRACT Jelmyto Registry: A Multicenter, Prospective and Retrospective Registry to Evaluate Real World Experience and Outcomes of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto","uTRACT","Inclusion Criteria:\n\n* Adults \\>18 years old and capable of giving informed consent.\n* Diagnosis of UTUC.\n* Receipt of at least 1 dose of JELMYTO after FDA approval (15 Apr 2020).\n\nExclusion Criteria:\n\n* Incapable of giving informed consent (e.g., incarcerated individuals, individuals with dementia).\n* Receipt of 1 or more doses of JELMYTO (also referred to as UGN-101 or Mitogel in clinical development) before FDA approval (on or before 15 Apr 2020).\n* Pregnancy or lactation.\n* Unable to comply with protocol requirements (for prospective data capture).\n* Any medical or mental condition(s) that makes participation in the Registry inadvisable in the opinion of the Investigator (for prospective data capture).","ALL","18 Years",{"count":349,"type":350},400,"ESTIMATED","3 Years","OBSERVATIONAL","The purpose of this registry is to evaluate real world experience and outcomes of patients with Upper Tract Urothelial Cancer (UTUC) treated with Jelmyto in the United States.",[355,356,357,358,359,360,361,362],"Urothelial Carcinoma","Urothelial Carcinoma Recurrent","Urothelial Carcinoma Ureter","Urothelial Carcinoma Ureter Recurrent","Urothelial Cancer of Renal Pelvis","Urothelial Carcinoma of the Renal Pelvis and Ureter","Carcinoma, Transitional Cell","Transitional Cell Carcinoma of Renal Pelvis",[364,365,21,366,367,368,369,370,371,372,373,374,375,376,377,378,379,380,381,382,383,384,385,386,387,388],"Upper Tract Urothelial Cancer","UTUC","Mitomycin C","TCC","Ureteral","Upper Tract","Carcinoma","Kidney","Renal","Gel","Local","Prolonged Release","Slow Release","Kidney Sparing","Recurrence","Neoplasms by Histologic Type","Neoplasms","Urologic Neoplasms","Urogenital Neoplasms","Neoplasms by Site","Antibiotics, Antineoplastic","Antineoplastic Agents","Alkylating Agents","Nucleic Acid Synthesis Inhibitors","Enzyme Inhibitors","2025-02-25",{"date":391,"type":392},"2025-02-28","ACTUAL",{"date":394,"type":392},"2023-11-17",{"date":396,"type":350},"2028-01",{"name":5,"class":6},22]