[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628473":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":29,"locations":38,"responsibleParty":63,"collaborators":20,"id":66,"slug":20,"hasResults":67,"nctId":68,"briefTitle":9,"officialTitle":9,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":67,"sex":71,"minAge":72,"maxAge":20,"enrollmentInfo":73,"targetDuration":20,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":84,"overallStatus":41,"whyStopped":20,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Northern Jiangsu People's Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection","EXPERIMENTAL","Procedure\u002FSurgery: vagus nerve-guided group The vagus nerve-guided procedure was performed in the following order: (1) find the left crural diaphragm; (2) via the surface of the left crural diaphragm, blunt dissect the left lateral surface of the distal esophagus using Bipolar Forceps, and find posterior vagal trunk; (3) along posterior vagal trunk towards left lateral esoph-agogastric junction, find and protect gastric and celiac branches; (4) enter the lesser omental sac from the right crural diaphragm using Bipolar Forceps; (5) transect the left gastric artery and vein together using a linear vascular stapler; (6) blunt dissect the anterior surface of the distal esophagus using Bipolar Forceps, and find anterior vagal trunk; (7) along anterior vagal trunk towards right lateral esoph-agogastric junction, find and protect gastric and hepatic branches; and (8) blunt dissect the right lateral surface of the distal esophagus. The hepatogastric ligament was conserved.",[13],"Procedure: Vagus nerve-guided laparoscopic splenectomy and azygoportal disconnection",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","Vagus nerve-guided laparoscopic splenectomy and azygoportal disconnection","The vagus nerve-guided procedure was performed in the following order: (1) find the left crural diaphragm; (2) via the surface of the left crural diaphragm, blunt dissect the left lateral surface of the distal esophagus using Bipolar Forceps, and find posterior vagal trunk; (3) along posterior vagal trunk towards left lateral esoph-agogastric junction, find and protect gastric and celiac branches; (4) enter the lesser omental sac from the right crural diaphragm using Bipolar Forceps; (5) transect the left gastric artery and vein together using a linear vascular stapler; (6) blunt dissect the anterior surface of the distal esophagus using Bipolar Forceps, and find anterior vagal trunk; (7) along anterior vagal trunk towards right lateral esoph-agogastric junction, find and protect gastric and hepatic branches; and (8) blunt dissect the right lateral surface of the distal esophagus. The hepatogastric ligament was conserved.",[9],null,[22,26],{"name":23,"affiliation":24,"role":25},"Dou-Sheng Bai, MD","Clinical Medical College, Yangzhou University","STUDY_CHAIR",{"name":27,"affiliation":24,"role":28},"Guo-Qing Jiang, MD","PRINCIPAL_INVESTIGATOR",[30,34],{"name":27,"role":31,"phone":32,"phoneExt":20,"email":33},"CONTACT","+86-514-87373272","jgqing2003@hotmail.com",{"name":35,"role":31,"phone":36,"phoneExt":20,"email":37},"Dou-sheng Bai, MD","86-514-87373275","bdsno1@hotmail.com",[39,58],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Clinical Medical College of Yangzhou University","RECRUITING","Yangzhou","Jiangsu","225001","China",{"type":47,"coordinates":48},"Point",[49,50],119.43583,32.39722,{"lat":50,"lon":49},[53,56],{"name":54,"role":31,"phone":55,"phoneExt":20,"email":33},"Guo-Qing Jiang, MS","86-514-87373372",{"name":23,"role":31,"phone":57,"phoneExt":20,"email":37},"86-514-87373375",{"facility":24,"status":59,"city":42,"state":43,"zip":44,"country":45,"cosmosGeoPoint":60,"geoPoint":62,"contacts":20},"COMPLETED",{"type":47,"coordinates":61},[49,50],{"lat":50,"lon":49},{"type":28,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Guo-Qing Jiang","Clinical Professor","100628473",false,"NCT07462091","VNLSD","Inclusion Criteria:\n\n1. A clinical, radiological or histologic diagnosis of cirrhosis of any etiology\n2. Splenomegaly with secondary hypersplenism\n3. Bleeding portal hypertension\n4. No evidence of portal vein system thrombosis by ultrasound evaluation and angio-CT\n5. Informed consent to participate in the study\n\nExclusion Criteria:\n\n1. Delayed gastric emptying\n2. Diarrhea\n3. Hepatocellular carcinoma or any other malignancy,\n4. Hypercoagulable state other than the liver disease related\n5. DRUGS- oral contraceptives, anticoagulation or anti-platelet drugs.\n6. Child - Pugh C\n7. Recent peptic ulcer disease\n8. History of Hemorrhagic stroke\n9. Pregnancy.\n10. Uncontrolled Hypertension\n11. Human immunodeficiency virus (HIV) infection","ALL","18 Years",{"count":74,"type":75},15,"ESTIMATED","INTERVENTIONAL",[78],"NA","This study aimed to evaluate the effectiveness and safety of vagus nerve-guided laparoscopic splenectomy and azygoportal disconnection, and to assess its impact on postoperative digestive complications and quality of life.",[81,82,83],"Cirrhosis","Hypersplenism","Hypertension, Portal",[85,86,81,87,88],"Laparoscopy","Vagus nerve","Azygoportal disconnection","Splenectomy","2026-03-26",{"date":91,"type":92},"2026-04-01","ACTUAL",{"date":94,"type":92},"2026-03-25",{"date":96,"type":75},"2027-03-31",{"name":5,"class":6},2]