Validation of a VOICE MAnagement Program in Schizophrenia VVoice MAPS

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre Hospitalier Universitaire de la Guadeloupe

About this trial

Approximately 25-50% of patients with schizophrenia experience treatment-resistant Auditory Verbal Hallucinations (AVHs), which contribute to the development of associated psychopathological disorders (e.g., anxiety, depression, suicidal ideation). Various validated psychotherapeutic strategies and tools for managing treatment-resistant AVHs have been combined into an integrative therapeutic program. The main objective of this study is to evaluate the efficacy of this program in reducing the frequency and intensity of AVHs, as well as its impact on comorbid psychopathology (e.g., depression, anxiety, self-esteem, substance use) in patients with schizophrenia or schizoaffective disorder who experience treatment-resistant AVHs.

Eligibility criteria

Qualifiers

Diagnosis: Fulfill DSM-5 criteria for schizophrenia or schizoaffective disorder.

Resistant AVHs: Present treatment-resistant auditory verbal hallucinations (AVHs), defined as the persistence of daily hallucinations without remission despite adequate antipsychotic medication for at least 3 months.

Motivation: Express a request for relief from voices.

Treatment Setting: Are outpatients being treated in psychiatric departments at the Public Mental Health Institution of Guadeloupe or the University Hospital Center of Nîmes.

Disqualifiers

Participation in another study: Currently taking part in another clinical trial or within the exclusion period of another study.

Consent refusal: Refuse to sign the written informed consent.

Inability to provide informed consent: Failure or impossibility to provide the patient with sufficient information to allow an informed decision.

Severe substance abuse: Presence of severe substance use disorder.

Trial design

Treatments tested in this trial

  • Integrative group therapy

Treatment groups

116 Participants
are divided into 2 treatment groups

Locations

1
Public Mental Health Institution of Guadeloupe97139, Les Abymes Guadeloupe

Sponsors and collaborators

Centre Hospitalier Universitaire de la Guadeloupe

Lead sponsor

GIRCI SOHO

Collaborator