About this trial

This observational study aims to validate the use of THz scanning system in corneal edema and corneal scars, and to investigate the accuracy and performance on the use of THz scanning system in the evaluation of the progression of corneal edema and corneal scars. Participants corneal scars and corneal edema will undergo THz scanning, followed by a series of conventional clinical examinations for detailed characterization of the corneal lesion. The performance of the use of THz system on corneal scars and edema will be evaluated by correlating measurements from the THz scans with those obtained from standard clinical methods. The investigators hypothesize that the THz scanning system has the capacity to evaluate the hydration level on human corneas.

Eligibility criteria

Qualifiers

Be at least 21 years of age.

Regardless of gender (Male/Female).

Regardless of race (Chinese/Malay/Indian/Eurasian/Others).

Willingness and ability to follow all instructions and comply with study schedule for study visit.

Disqualifiers

Eyes with active inflammation or infection, or chronic ocular surface inflammation

Unable to give consent

Physically immobile/poor instructional compliance

PI determined

Trial design

Treatments tested in this trial

  • THz scanning using THz Imaging system.

Treatment groups

150 Participants
are divided into 2 treatment groups

Locations

1
Singapore National Eye CentreS169856, Singapore Singapore

Sponsors and collaborators

Singapore Eye Research Institute

Lead sponsor