[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100371709":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":60,"collaborators":25,"id":62,"slug":25,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":63,"sex":69,"minAge":70,"maxAge":25,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":44,"whyStopped":25,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"University Hospital, Lille","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with haemorrhagic disease","EXPERIMENTAL","Patients with von Willebrand disease or Patients with Glanzmann Thrombasthenia",[13,14],"Device: Sublingual videomicroscopy","Biological: blood sample",{"label":16,"type":6,"description":17,"interventionNames":18},"Control group","Patients with moderate or severe hemophilia A or women carrying the hemophilia gene",[13],[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Sublingual videomicroscopy","Measurement of sublingual capillary density by video microscopy",[16,9],null,{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":25},"BIOLOGICAL","blood sample","Collection of citrate tubes of 5 mL at baseline and at 36 months",[9],[32],{"name":33,"affiliation":5,"role":34},"Antoine Rauch, MD,PhD","PRINCIPAL_INVESTIGATOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":39,"email":40},"CONTACT","3 20445962 (poste 29673)","+33","antoine.rauch@chru-lille.fr",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"CHU de Lille","RECRUITING","Lille","Nord","59000","France",{"type":50,"coordinates":51},"Point",[52,53],3.05512,50.63391,{"lat":53,"lon":52},[56,58],{"name":57,"role":37,"phone":25,"phoneExt":25,"email":25},"Antoine Rauch, MD",{"name":59,"role":34,"phone":25,"phoneExt":25,"email":25},"Antoine Rauch, md",{"type":61,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100371709",false,"NCT04119908","Videomicroscopy for the Prediction of Bleeding in Constitutional Haemorrhagic Diseases","Interest of Sublingual Videomicroscopy for the Prediction of Bleeding in Von Willebrand Disease and Other Constitutional Haemorrhagic Diseases","VIDEO-BLEED","Inclusion Criteria:\n\n* Adult patient with a significant form of von Willebrand disease (according to the inclusion criteria of the Willebrand Disease French Reference Center), a Glanzmann Thrombasthenia, a moderate to severe Haemophilia A or a woman carrying the hemophilia gene\n* Social insured patient\n\nExclusion Criteria:\n\n* Minor patient\n* Refusal of consent\n* Person benefiting from a system of legal protection\n* Pregnant patient","ALL","18 Years",{"count":72,"type":73},400,"ESTIMATED","INTERVENTIONAL",[76],"NA","In Willebrand disease, there is currently no test available to identify non-invasively patients with a high risk of bleeding from angiodysplasias The study propose to use a sublingual capillary bed analysis by video-microscopy, a sensitive, reproducible and non-invasive technique, to assess whether sublingual capillary density is predictive of hemorrhagic risk for patients with von Willebrand disease.",[79,80],"Von Willebrand Diseases","Glanzmann Thrombasthenia",[82,83,84,85],"constitutional haemorrhagic diseases, Videomicroscopy, prediction, bleeding","Videomicroscopy","prediction","bleeding","2026-05-19",{"date":88,"type":89},"2026-05-20","ACTUAL",{"date":91,"type":89},"2023-05-24",{"date":93,"type":73},"2028-05-24",{"name":5,"class":6},1]