About this trial
Brachial plexus birth injury (BPBI) is a condition that occurs when the nerves controlling the arm are injured during birth, leading to weakness, limited movement, and sensory problems. These motor difficulties may also affect cognitive processes related to movement. BPBI requires long-term follow-up and rehabilitation.
This study will compare two treatment approaches in children with BPBI:
* virtual reality (VR)-based exercises, and * motor-cognitive dual-task exercises. We will examine their effects on brain adaptation (cortical activation), muscle strength, joint motion, proprioception, and upper-limb function. Fourteen children aged 7-14 years will be randomly assigned to one of the two programs, each delivered for 12 weeks. Afterward, participants will continue a 9-month home program. Assessments will be conducted at baseline, after treatment, and at 12 months, including functional MRI (fMRI).
This study will be the first to evaluate long-term brain changes and functional outcomes after these two rehabilitation approaches in children with BPBI.
Eligibility criteria
Qualifiers
Children aged 7-14 years
Diagnosed with unilateral DBPP
C5-C6 or C5-C7 involvement (Narakas I, IIa, IIb)
Modified Pediatric Mini-Mental Scale score ≥26
Disqualifiers
Previous nerve surgery for DBPP
Surgery within the past year or Botulinum Toxin injection within the past 3 months
Any neurological condition other than DBPP
Vision or hearing impairments affecting participation
Trial design
Treatments tested in this trial
- Conventional Physiotherapy Program
- Virtual Reality
- Dual Task
Treatment groups
Locations
Sponsors and collaborators
Istanbul Aydın University
Lead sponsor
Istanbul University
Collaborator
Biruni University
Collaborator