[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100429797":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":11,"centralContacts":11,"locations":31,"responsibleParty":54,"collaborators":11,"id":56,"slug":11,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":11,"enrollmentInfo":65,"targetDuration":11,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":11,"overallStatus":34,"whyStopped":11,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"University Hospital, Basel, Switzerland","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"0.5 liters of alcoholic beer","EXPERIMENTAL",null,[13],"Other: Beer",{"label":15,"type":16,"description":11,"interventionNames":17},"0.5 liters of water","PLACEBO_COMPARATOR",[18],"Other: Water",{"label":20,"type":21,"description":11,"interventionNames":11},"non-interventional cohort control group","NO_INTERVENTION",[23,27],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":11},"Beer","As interventive agent 0.5 L organic alcohol-containing wheat beer produced by the brewery \"Unser Bier\" in Basel, Switzerland, is administered once a day at 8pm for 6 consecutive days after enrolment.",[9],{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":11},"Water","For the interventional control group 0.5L water is administered once a day at 8pm for 6 consecutive days after enrolment.",[15],[32],{"facility":33,"status":34,"city":35,"state":11,"zip":36,"country":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"University Hospital Basel","RECRUITING","Basel","4031","Switzerland",{"type":39,"coordinates":40},"Point",[41,42],7.57327,47.55839,{"lat":42,"lon":41},[45,50],{"name":46,"role":47,"phone":48,"phoneExt":11,"email":49},"Martin Siegemund, Prof","CONTACT","0041613286414","martin.siegemund@usb.ch",{"name":51,"role":47,"phone":52,"phoneExt":11,"email":53},"Alexa Hollinger, PD Dr","0041615565895","alexa.hollinger@usb.ch",{"type":55,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100429797",false,"NCT04876742","Wheat Beer for Prevention of Delirium in Intensive Care Patients","A Randomised Placebo-controlled Double-blind Exploratory Trial Within Cohort Using Wheat Beer for Prevention of Delirium in Intensive Care Patients","BABE-D","Inclusion criteria\n\nAll Patients meeting the following criteria are eligible for the study:\n\n* Risk of delirium: ICU patients with expected length of stay (LOS) ≥ 24 hours\n* Naso-gastric tube in situ\n* ICU stay ≤ 72h until first study intervention\n* Women: negative pregnancy test, age ≥50 years or status post hysterectomy\u002Fbilateral ovariectomy\n* Adult patients (age ≥ 18 years)\n* ≥ 50 kg body weight or BMI ≥18.5\n\nExclusion Criteria\n\nPatients fulfilling the following criteria are excluded from the study:\n\n* Pre-existing liver pathologies\n* Patients after bone marrow transplantation\n* Women: breastfeeding\n* Pre-existing delirium (ICDSC ≥ 4)\n* Terminal state\n* Active psychosis\n* Anamnestic complete alcohol abstinence or status post alcohol abuse\n* Especially vulnerable patients\n* Allergy to any ingredient(s) of beer","ALL","18 Years",{"count":66,"type":67},380,"ESTIMATED","INTERVENTIONAL",[70],"NA","The investigators hypothesise that the daily administration of 0.5L alcohol-containing wheat beer at 8 pm over a study period of 6 days in a row leads to a lower prevalence of delirium compared to water following the same administration scheme.",[73],"ICU Delirium","2026-06-10",{"date":76,"type":77},"2026-06-11","ACTUAL",{"date":79,"type":77},"2023-01-18",{"date":81,"type":67},"2029-12-31",{"name":5,"class":6},1]