[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ankle-fractures\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ankle-fractures":495},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,18,0,[8,48,74,103,132,162,213,234,254,284,308,330,352,374,399,418,438,468],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100642817",false,"NCT07620015","Turkish Version of the Ankle Fracture Outcome of Rehabilitation Measure (A-FORM-TR): A Multi-Centre Validation Study","Cross-Cultural Adaptation and Psychometric Validation of the Turkish Version of the Ankle Fracture Outcome of Rehabilitation Measure (A-FORM-TR): A Multi-Centre Prospective Observational Study","A-FORM-TR","Inclusion Criteria:\n\n* Age 18 years or older\n* Radiographically confirmed unilateral ankle fracture (Weber A, B, or C)\n* Either surgical (open reduction and internal fixation) or conservative (cast, walker boot, or functional brace) treatment completed\n* Currently in the rehabilitation phase, 3 weeks to 12 months post-injury\n* Native Turkish speaker, able to read and self-complete a questionnaire\n* Able and willing to provide written informed consent\n\nExclusion Criteria:\n\n* Bilateral ankle fracture\n* Previous ipsilateral ankle fracture or any prior orthopedic surgery on the same ankle\n* Pathological fracture (tumour, metastasis, or other underlying bone pathology)\n* Concurrent significant ipsilateral lower-limb injury (for example pilon fracture, ipsilateral tibial or fibular shaft fracture, ipsilateral femoral or tibial plateau fracture)\n* Polytrauma (significant head, spine, abdominal, or contralateral lower-limb injury affecting function)\n* Cognitive or psychiatric impairment precluding self-completion of the questionnaire\n* Insufficient Turkish literacy\n* Inability to attend a follow-up visit for the test-retest assessment","ALL","18 Years",{"count":19,"type":20},150,"ESTIMATED","OBSERVATIONAL","Ankle fractures are common injuries that can affect a patient's mobility, mood, sleep, and everyday life for months. The Ankle Fracture Outcome of Rehabilitation Measure (A-FORM) is an English-language patient-reported outcome measure developed in Australia to capture this broader rehabilitation experience. No validated Turkish version of A-FORM currently exists. This prospective multi-centre observational study aims to translate the A-FORM into Turkish (A-FORM-TR), culturally adapt it for use in Turkish-speaking patients, and evaluate its psychometric properties. The investigators will recruit 150 adults with a unilateral ankle fracture, treated either surgically or conservatively, from three orthopedic centres in Turkiye and the Turkish Republic of Northern Cyprus. Participants complete the A-FORM-TR together with two established comparator questionnaires (AOFAS Ankle-Hindfoot Score and the Turkish Olerud-Molander Ankle Score). A subset of approximately 50 participants is re-administered the A-FORM-TR after 7 to 14 days to assess test-retest reliability, with a Global Rating of Change item identifying clinically stable patients. Analyses include classical test theory, confirmatory factor analysis, and Rasch measurement analysis.",[24,25],"Ankle Fractures","Ankle Injuries",[27,28,29,30,31,32,33,34],"patient-reported outcome measure","PROM","cross-cultural adaptation","psychometric validation","ankle fracture","rehabilitation","Rasch analysis","Turkish","NOT_YET_RECRUITING","2026-06-09",{"date":38,"type":39},"2026-06-12","ACTUAL",{"date":41,"type":20},"2026-08",{"date":43,"type":20},"2027-07",{"name":45,"class":46},"Utku Gürhan","OTHER",3,{"id":49,"slug":4,"hasResults":10,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":73},"100460823","NCT05280639","Simplified Post Op Rehabilitation for Ankle and Pilon Fractures","Ankle and Pilon Fracture Post Operative Rehabilitation: A Randomized Control Trial Exploring a Simplified Wooden Block Protocol","Inclusion Criteria:\n\n* Ages 18-65\n* Surgically treated open or closed fractures of the ankle or tibial plafond\n\nExclusion Criteria:\n\n* Contralateral lower extremity injuries that would limit weight bearing after 6 weeks\n* Severe injury requiring flap coverage or vascular reconstruction (Gustilo-Anderson Type IIIB and C respectively)\n* Neurological deficits that would impede ability to stand safely unassisted for home exercise regiment\n* Desire to participate in formal physical therapy program\n* Additional injury that would compromise subjects ability to follow either Home Exercise Program\n* Non ambulatory prior to injury\n* Previous ankle or tibial plafond injury on ipsilateral extremity\n* BMI \\> 50\n* Severe problems maintaining follow up\n* Previous ankle\u002Ftibial plafond fracture\n* Prisoners\n* Neurological impairments that impair balance","65 Years",{"count":56,"type":20},30,"INTERVENTIONAL",[59],"NA","The aim of this study is to compare standard post operative rehabilitation with a simplified wooden block stretching protocol that will yield similar results.",[24,62],"Pilon Fracture","RECRUITING","2026-06-05",{"date":66,"type":39},"2026-06-08",{"date":68,"type":39},"2022-10-03",{"date":70,"type":20},"2027-06-01",{"name":72,"class":46},"University of Virginia",1,{"id":75,"slug":4,"hasResults":10,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":10,"sex":16,"minAge":4,"maxAge":79,"enrollmentInfo":80,"targetDuration":4,"studyType":57,"phases":82,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":73},"100629382","NCT07473947","Performance and Safety Follow-up of Bioabsorbable Headless Inion CompressOnTM Screws in the Fixation of Bone Fractures in Ankle, Knee and Elbow of Pediatric and Adolescent Patients","Inclusion Criteria:\n\n1\\. Informed consent signed by parents or legal guardians, and assent from the child if of appropriate age and cognitive ability \\\u003C 18 years 3. Suitable and in need for an operation indicated for subject device 4. Ability to give adequate input for the PROM questionnaires 5. Willingness and ability to comply with rehabilitation instructions. 6. Availability for follow-up visits.\n\nExclusion Criteria:\n\n1. Active infection\n2. Patient conditions including limited blood supply (e.g. patients with severe circulatory disorder of the lower or upper limb)\n3. Patient conditions including insufficient quality or quantity of bone (diagnosed osteoporosis, conditions causing secondary osteoporosis e.g. diabetes, rheumatism, eating disorder)\n4. Patient conditions where patient cooperation cannot be guaranteed (alcohol use, drug abuse etc.)\n5. Patients with known allergy to the implant constituents or its degradation products.\n6. Spinal and craniomaxillofacial indications.\n7. High-load bearing indications (e.g., diaphyseal fractures of long bones) unless used in conjunction with traditional rigid fixation","17 Years",{"count":81,"type":20},80,[59],"The study in question is a post market clinical follow up (PMCF) study to follow up the safety and performance of bioabsorbable headless compression screw Inion CompressOn in fracture fixation of the ankle, knee and elbow of pediatric and adolescent patients. The study aims to recruit 80 patients who meet the acceptance criteria. The follow-up time for each study patient is 4 years. The study is a single center single group study which is conducted in Lighthouse Hospital at Turku University Hospital (TYKS) in Finland. The main focus of the study in terms of performance is to follow up the bone healing\u002Fossification of operated areas. The main focus of the study in terms of safety is to evaluate the occurrence of adverse events and required revision surgeries that are or might be related to the study device.",[24,85,86],"Knee Fractures","Elbow Fractures",[88,89,31,90,91,92],"bioabsorbable","resorbable","knee fracture","elbow fracture","fracture fixation","2026-06-01",{"date":95,"type":39},"2026-06-03",{"date":97,"type":39},"2026-05-29",{"date":99,"type":20},"2032-12",{"name":101,"class":102},"Inion Oy","INDUSTRY",{"id":104,"slug":4,"hasResults":10,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":54,"enrollmentInfo":109,"targetDuration":4,"studyType":57,"phases":111,"briefSummary":112,"conditions":113,"keywords":116,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":73},"100629945","NCT07481266","Single-Window Versus Two-Window Posterolateral Approach for Malleolar Fractures","Comparison of Single-Window and Two-Window Posterolateral Approaches in Posterior and Lateral Malleolus Fractures: A Clinical Outcomes Analysis","Inclusion Criteria:\n\n* Patients aged between 18 and 65 years.\n* Diagnosis of an acute, closed, unstable rotational ankle fracture with concomitant involvement of the posterior malleolus and lateral malleolus (trimalleolar or bimalleolar equivalent fractures).\n* Fracture morphology explicitly indicating surgical reduction and internal fixation via a posterolateral approach (e.g., Bartonicek Type II, III, or IV).\n* Ability to provide informed consent and willingness to comply with the 12-month postoperative rehabilitation and follow-up protocol.\n\nExclusion Criteria:\n\n* Open fractures, severe tibial pilon variants, or fractures with intra-articular comminution extending beyond the posterior malleolus.\n* Persistent Syndesmotic Instability: Patients demonstrating persistent distal tibiofibular syndesmotic instability (confirmed by intraoperative hook test) after the fixation of the posterior and lateral malleoli, which inherently requires additional trans-syndesmotic fixation (e.g., syndesmotic screws or suture-button devices). This exclusion is strictly applied to eliminate methodological bias, as the experimental single-window approach intentionally restricts direct lateral access for trans-syndesmotic interventions.\n* Delayed surgical intervention exceeding 7 days from the initial trauma, leading to organized hematoma or compromised soft-tissue envelopes.\n* Pre-existing conditions detrimental to soft-tissue healing and functional assessment, including severe peripheral arterial disease, uncontrolled diabetes mellitus with neuropathy, or severe ipsilateral ankle osteoarthritis.\n* Previous history of ipsilateral ankle fractures or surgeries.",{"count":110,"type":20},100,[59],"The purpose of this prospective clinical trial is to compare the clinical outcomes and early wound complication rates of two different surgical techniques used during the posterolateral approach for ankle fractures. Participants with fractures involving the posterior and lateral malleoli will undergo surgery using either a single-window technique (using a posterior antiglide plate) or a two-window technique (using a lateral anatomic plate). The main question the study aims to answer is whether the single-window approach reduces soft-tissue complications by minimizing surgical dissection, without compromising fracture stability. Patients will be followed for 12 months to assess wound healing, ankle range of motion, implant irritation, and functional recovery.",[24,114,115],"Posterior Malleolus Fractures","Lateral Malleolus Fracture",[117,118,119,120,121,122,24],"Posterolateral approach","Single-window technique","Posterior antiglide plate","Two-window technique","Wound complication","Trimalleolar fracture","2026-03-18",{"date":125,"type":39},"2026-03-20",{"date":127,"type":39},"2024-02-14",{"date":129,"type":20},"2027-03",{"name":131,"class":46},"muhammed kılıç",{"id":133,"slug":4,"hasResults":10,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":4,"eligibilityCriteria":137,"healthyVolunteers":138,"sex":16,"minAge":139,"maxAge":4,"enrollmentInfo":140,"targetDuration":4,"studyType":57,"phases":142,"briefSummary":143,"conditions":144,"keywords":151,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":155,"startDateStruct":156,"completionDateStruct":158,"leadSponsor":160,"locationsCount":73},"100522666","NCT06085586","Fibulink Syndesmosis Repair System With Early Full-Weight Bearing","Evaluation of Safety and Performance Outcomes of the Fibulink Syndesmosis Repair System With Early Full-Weight Bearing","Inclusion Criteria:\n\n* ankle fracture with syndesmotic disruption as assessed with intra-operative cotton test.\n\nThis includes the following injuries:\n\n* Syndesmotic sprain (without fractures)\n* Bimalleolar equivalent ankle fractures\n* Bimalleolar ankle fractures\n* Maisonneuve fractures\n* Trimalleolar ankle fractures without the need for posterior malleolus fixation\n* Ankle fracture dislocations\n\nExclusion Criteria:\n\n* 1\\) previous ankle surgery, 2) active local infection about the ankle, 3) chronic ankle deformity secondary to trauma or congenital, 4) ligamentous laxity, 5) pathologic fractures, 6) peripheral vascular disease, 7) peripheral neuropathy, 8) diabetes neuropathy and charcot, 9) open fractures, 10) poly trauma, 11) inability to provide informed consent, 12) symptomatic ankle osteoarthritis, 12) retained hardware, 13) pregnant, 14) metabolic bone disease, 15) history of chronic steroid use, 16) mal-reduced ankle fractures",true,"22 Years",{"count":141,"type":20},56,[59],"The purpose of the study is to evaluate the ability of the Fibulink Syndesmosis Repair System to maintain reduction of the ankle syndesmosis. Appropriate reduction of the syndesmosis is critical due the changes in tibiotalar contact pressure observed in cadaveric studies.6,7 Malreduction and instability of the distal tibiotalar joint can lead to chronic instability, increased articular damage and ultimately degenerative arthritis.7,8 Medial to lateral translation of distal tibia and fibula of 2 mm or more has been considered pathologic.9 Earlier biomechanical study demonstrated the Fibulink system is superior in maintaining displacement of less than 2 mm.4 Given the improved strength, we also look to evaluate the outcomes of initiating full weight bearing (100%) with Controlled Ankle Motion (CAM) boot at 4 weeks postoperatively. One of the big limitations for trans-osseous screw fixation is delayed weight bearing due to risk of screw breakage.1 Suture button technique allowed for early weight bearing with average of 6 weeks postoperatively using TightRope.2,10-12By initiating full weight bearing (100%) with CAM boot at 4 weeks postoperatively, this would be a significant improvement in current clinical practice.",[24,145,146,147,148,149,150],"Bimalleolar Fractures","Syndesmotic Injuries","Bimalleolar Equivalent Fracture","Maisonneuve Fracture","Trimalleolar Fractures","Ankle Dislocation",[24,145,147,149,152,146,153],"Maisonneuve Fractures","Ankle Dislocations","2026-03-17",{"date":125,"type":39},{"date":157,"type":39},"2023-07-13",{"date":159,"type":20},"2026-12-31",{"name":161,"class":46},"Maimonides Medical Center",{"id":163,"slug":4,"hasResults":10,"nctId":164,"briefTitle":165,"officialTitle":166,"acronym":4,"eligibilityCriteria":167,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":168,"targetDuration":4,"studyType":57,"phases":170,"briefSummary":171,"conditions":172,"keywords":191,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":205,"lastUpdatePostDateStruct":206,"startDateStruct":208,"completionDateStruct":210,"leadSponsor":212,"locationsCount":73},"100481933","NCT05555459","Performance and Safety Evaluation of Inion CompressOn Screw in Foot and Ankle Surgeries. PMCF Investigation","The Performance and Safety Evaluation of Bioabsorbable Headless Inion CompressOn Screws in Selected Fracture, Osteotomy and Artrodesis Surgeries of the Foot and Ankle","Inclusion Criteria:\n\n1. Read the patient information bulletin on the study and signed the patient consent form\n2. Adult patient (over 18-year-old)\n3. Suitable and in need for surgical lower limb operation listed in the indications of this study that requires fastening of bone structures with screws (or an alternative attachment method) in the ankle or foot area, according to a statement of the investigator surgeon\n4. Ability to fill in questionnaires.\n5. Willingness to comply with rehabilitation instructions.\n6. Availability for follow-up visits.\n\nExclusion Criteria:\n\n1. Active infection\n2. Patient conditions including limited blood supply (e.g. patients with severe circulatory disorder of the lower limb\n3. Patient conditions including insufficient quality or quantity of bone (diagnosed osteoporosis, conditions causing secondary osteoporosis e.g. diabetes, rheumatism, eating disorder)\n4. Patient conditions where patient cooperation cannot be guaranteed (alcohol use, drug abuse etc.)\n5. High-load bearing indications (e.g., diaphyseal fractures of long bones) unless used in conjunction with traditional rigid fixation\n6. Patients with significant neuropathy\n7. Pregnancy\n8. Patients who refuse to participate\n9. Lower limb tumor or metastasis\n10. Complex Regional Pain Syndrome (CRPS) in operated foot",{"count":169,"type":20},125,[59],"The study in question is a post market clinical follow up (PMCF) study to evaluate the safety and performance of bioabsorbable headless compression screw Inion CompressOn in selected fracture, osteotomy and arthrodeses operations of the foot and ankle. The study recruits 125 adult patients who meet the acceptance criteria. The follow-up time for each study patient is 4 years. The study is a single center single group study which is conducted in Tampere University Hospital (TAYS) in Finland. The main focus of the study in terms of performance is to evaluate the bone healing\u002Fossification of operated areas. The main focus of the study in terms of safety is to evaluate the occurrence of adverse events and required revision surgeries that are or might be related to the study device.",[173,174,175,176,177,178,179,24,180,181,182,183,184,185,186,187,188,189,190],"Medial Malleolus Fracture","Lisfranc Injury","Lisfranc Fracture","Talus Fracture","Calcaneus Fracture","Navicular Fracture","Deformity, Foot","Foot Fracture","Fractures, Bone","Fracture of Foot","Foot Deformities","Foot Injury","Feet Deformity Tarsus","Metatarsalgia","Hallux Rigidus","Hallux Valgus","Deformity of Toe","Deformity of Foot",[192,193,194,195,196,197,89,198,88,199,200,201,202,203,204],"bioabsorbable screw","compression screw","headless screw","orthopaedic screw","bone fixation","bioabsorbable screw study","biodegradable","fracture fixation with resorbable implants","inion","post-market follow-up study","orthopedic bone fixation","arthrodesis","osteotomy","2026-03-11",{"date":207,"type":39},"2026-03-13",{"date":209,"type":39},"2023-03-07",{"date":211,"type":20},"2032-04-30",{"name":101,"class":102},{"id":214,"slug":4,"hasResults":10,"nctId":215,"briefTitle":216,"officialTitle":217,"acronym":4,"eligibilityCriteria":218,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":219,"enrollmentInfo":220,"targetDuration":4,"studyType":57,"phases":222,"briefSummary":223,"conditions":224,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":225,"lastUpdatePostDateStruct":226,"startDateStruct":228,"completionDateStruct":230,"leadSponsor":232,"locationsCount":73},"100544549","NCT06370325","Neuromuscular Electrical Stimulation in Foot and Ankle Surgery","Neuromuscular Electrical Stimulation in Foot and Ankle Surgery: A Pilot Study","Inclusion Criteria:\n\n* Capable and willing to provide informed consent\n* Undergoing a procedure that involves repairing an ankle fracture.\n\nExclusion Criteria:\n\nPatients with medical histories that include:\n\n* Rheumatoid arthritis\n* Connective tissue disorders\n* Chronic corticosteroid use\n* Implanted electrical devices\n* Neurological disorders\n* Non-ambulatory status\n* Recent surgery (within the last 3 months) that is not related to the study\n* Scheduled to undergo surgery in the near future\n* Epilepsy\n* Diagnosed with cancer\n* Have suffered acute trauma or recently have had a surgical procedure (not related to the study)\n* Have cardiac problems or cardiac disease\n* Have an abdominal hernia\n* Have venous thrombosis","70 Years",{"count":221,"type":20},20,[59],"This is a pilot randomized controlled trial, wherein the intervention group will undergo NMES five days a week beginning three weeks postoperative and lasting for ten weeks. Both the control and intervention groups will start standard physical therapy six weeks postoperative. Primary outcome measure will be the isometric strength of the gastrocnemius muscle. The secondary outcomes will comprise subjective clinical evaluations (using the Lower Extremity Functional Scale \\[LEFS\\]), functional assessments such as the sit-to-stand test, 2-minute walk test, stair climb test and objective clinical evaluation using contralateral comparison of calf circumference.",[24],"2026-02-25",{"date":227,"type":39},"2026-02-27",{"date":229,"type":39},"2025-06-19",{"date":231,"type":20},"2026-12-30",{"name":233,"class":46},"NYU Langone Health",{"id":235,"slug":4,"hasResults":10,"nctId":236,"briefTitle":237,"officialTitle":238,"acronym":4,"eligibilityCriteria":239,"healthyVolunteers":138,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":240,"targetDuration":4,"studyType":57,"phases":242,"briefSummary":243,"conditions":244,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":245,"lastUpdatePostDateStruct":246,"startDateStruct":248,"completionDateStruct":250,"leadSponsor":252,"locationsCount":73},"100495312","NCT05729542","Comparing Clinical Outcomes of Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries","Randomized Controlled Trial Comparing Clinical Outcomes of Patients Treated Surgically With Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries","Inclusion Criteria:\n\n* Ankle fracture with associated syndesmotic injury requiring surgery\n* Age 18 years or older\n* Ability to understand the content of the patient information\u002Finformed consent form\n\nExclusion Criteria:\n\n* Any not medically managed severe systemic disease\n* Patient preference for specific implant\n* Refusal of randomization\n* Pregnant patients\n* Prisoners\n* Participation in any other pharmacologic or medicinal product study within the previous month that could influence the results of this study",{"count":241,"type":20},140,[59],"This project consists of a randomized controlled study design. Study candidates will include all patients 18 years or older, who were evaluated at UCSD and found to have an acute ankle syndesmosis injury requiring surgery. Patients who consent to study participation will be randomized to receive one of two standard of care procedures - either a suture button or Fibulink implant. Outcome measures, including the Olerud-Molander and American Orthopaedic Foot and Ankle Society scores, pain, range of motion, time to return to work, and radiographic evaluation will be collected for each participant. Given the potential degenerative changes and poor radiographic and clinical outcomes with inadequate repair of the syndesmosis, it is imperative to evaluate existing and emerging methods of fixation for patients with acute ankle fractures with syndesmosis injuries.",[25,146,24],"2026-02-05",{"date":247,"type":39},"2026-02-10",{"date":249,"type":39},"2021-11-18",{"date":251,"type":20},"2027-12-31",{"name":253,"class":46},"University of California, San Diego",{"id":255,"slug":4,"hasResults":10,"nctId":256,"briefTitle":257,"officialTitle":258,"acronym":259,"eligibilityCriteria":260,"healthyVolunteers":10,"sex":16,"minAge":261,"maxAge":4,"enrollmentInfo":262,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":264,"conditions":265,"keywords":266,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":275,"lastUpdatePostDateStruct":276,"startDateStruct":278,"completionDateStruct":280,"leadSponsor":282,"locationsCount":73},"100449349","NCT05131321","FRAME Study (Frailty-Related Ankle Fracture Management and Evaluation)","FRAME Study (Frailty-Related Ankle Fracture Management and Evaluation): Retrograde Nailing Versus Open Reduction and Internal Fixation for Unstable Fractures Around the Ankle in the Frail Elderly - A Two-Part Prospective, Randomized, Multi-Center Clinical Trial","FRAME","Patient Inclusion Criteria - Both Parts:\n\n(i) Age ≥ 60 years (ii) One or more of the following:\n\n* Severe soft tissue compromise\n* Significant co-morbidities (vascular disease + chronic trophic changes, diabetes + neuropathy, chronic renal failure, morbid obesity (BMI\\> 40))\n* Frailty as defined by a Dalhousie Clinical Frailty Scale score ≥4\n\nPart 1 Specific Inclusion Criteria:\n\n(i) Isolated fracture (within 4 weeks of injury): an AO\u002FOTA type 43C2 or C3 tibial pilon fracture or severe ankle fracture (fracture-dislocation, severe joint impaction, severe trimalleolar)\n\nPart 2 Specific Inclusion Criteria (i) Isolated fracture (within 4 weeks of injury): an AO\u002FOTA type 44B2, B3, C1 or C2 ankle fracture\n\nPatient Exclusion Criteria - Both Parts:\n\n(i) Presence of vascular injury or pathologic fracture; (ii) Previous tibia pilon fracture or retained hardware in affected limb; (iii) Refusal to participate; (iv) Inability to obtain informed consent due to language barrier","40 Years",{"count":263,"type":20},172,"This will be a multi-centre randomized controlled trial, with London Health Sciences Centre (LHSC) as the lead site. Elderly patients with complex ankle fractures who meet the inclusion criteria and provide consent will be randomized (through a web-based randomization system) to one of the two treatment arms. One group (Group A) will receive primary ankle fusion, and the second group (Group B) will receive primary ankle open reduction and internal fixation (ORIF). Patient important outcomes will be compared at one year post injury\n\nThe Investigators have amended the study to include a second part for patients with less complicated but still unstable ankle fractures. In this part, patients will be randomly assigned to receive either a procedure called ORIF or another one called retrograde intramedullary fibular nailing.",[24,62],[267,268,269,270,271,272,273,274],"Complex ankle fracture","Pilon fracture","Primary Ankle Arthrodesis","Fragility fracture","Elderly","Open reduction","Internal fixation","AO\u002FOTA type 44B2, B3, C1 or C2 ankle fracture","2026-01-26",{"date":277,"type":39},"2026-01-28",{"date":279,"type":39},"2022-04-21",{"date":281,"type":20},"2028-12",{"name":283,"class":46},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's",{"id":285,"slug":4,"hasResults":10,"nctId":286,"briefTitle":287,"officialTitle":287,"acronym":288,"eligibilityCriteria":289,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":290,"enrollmentInfo":291,"targetDuration":4,"studyType":57,"phases":293,"briefSummary":294,"conditions":295,"keywords":296,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":299,"lastUpdatePostDateStruct":300,"startDateStruct":302,"completionDateStruct":304,"leadSponsor":306,"locationsCount":73},"100606248","NCT07173088","Efficacy and Clinical Feasibility of the Ankle Muscle Power (AMP) Program for Return to Duty After an Ankle Fracture","AMP","Inclusion Criteria:\n\n* Age 18-50 years old\n* Acute orthopedic injury to the ankle requiring surgical fixation\n* Must have stable address and phone number to schedule follow up contact visits\n* English speaking\n* BMI ≤ 35 kg\u002Fm2\n\nExclusion Criteria:\n\n* History of chronic pain defined as pain lasting more than 3 months and bothersome at least half the days over the past 6 months that started before the fracture\n* Moderate or severe traumatic brain injury\n* Initial treatment requiring amputation\n* Spinal cord injury\n* Unable to speak or read English\n* History of schizophrenia, dementia, neurologic disorder with peripheral dysfunction, or other psychotic disorder based upon medical record or patient self-report\n* Any chronic conditions that would limit their ability to participate in an intervention\n* Multiple trauma that prevents engaging in intervention\n* Pregnant\n* Unable to participate in or complete in-person follow up visits or therapy sessions\n* In Physical Therapy at the start of the intervention.\n* Use of an assistive device to walk for community ambulation\n* Prior lower extremity fracture within the past 2 years","50 Years",{"count":292,"type":20},60,[59],"The goal of this clinical trial is to compare two different standardized physical therapy rehabilitation programs on outcomes after an ankle fracture. Researchers will evaluate to see if the addition of ankle muscle power exercises (AMP) improve program adherence, muscle function, physical performance, and patient reported outcomes. The main questions it aims to answer are:\n\n1. Assess feasibility and define the initial effects of the AMP program on ankle plantar flexor rate of torque development and ankle power.\n\n   Primary hypothesis: an ankle muscle power program will have acceptable feasibility through assessment of 80% adherence, 90% treatment fidelity, recruitment (48 participants who complete the study), 80% retention, and 80% acceptability of the AMP program to facilitate clinical translation and the ability to scale-up the treatment. In addition ankle plantar flexor muscle power, plantar flexor RTD assessed isometrically, and ankle joint power, evaluated during gait and stair ascent\u002Fdescent, will have significantly greater improvements in the AMP group than the standard of care group at the end of the intervention.\n2. Test the effect of the AMP program on physical performance. Primary hypothesis: those completing the AMP program will have greater improvements in the 40 meter fast paced walk test and 11-stair climb test than those completing standard of care at the completion of the intervention.\n3. Assess the preliminary efficacy of the AMP program on patient reported outcomes and quality of life.\n\nPrimary hypothesis: compared to standard of care, the AMP program will result in improved quality of life on the ankle fracture outcome rehabilitation measure (A-FORM)\n\nParticipants will complete rehabilitation and be assessed for outcomes at baseline and after completing the intervention. Additionally exploratory outcomes will be assessed 3 months after completing the intervention.",[24],[297,298],"Physical Therapy","Rehabilitation","2025-11-24",{"date":301,"type":39},"2025-12-02",{"date":303,"type":39},"2025-11-13",{"date":305,"type":20},"2028-03",{"name":307,"class":46},"Brian W. Noehren",{"id":309,"slug":4,"hasResults":10,"nctId":310,"briefTitle":311,"officialTitle":312,"acronym":4,"eligibilityCriteria":313,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":314,"enrollmentInfo":315,"targetDuration":4,"studyType":57,"phases":317,"briefSummary":319,"conditions":320,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":321,"lastUpdatePostDateStruct":322,"startDateStruct":324,"completionDateStruct":326,"leadSponsor":328,"locationsCount":73},"100339184","NCT03696199","Randomized Controlled Trial for Ankle Fracture Pain Control","A Prospective, Randomized Trial Evaluating Regional Anesthesia, Long-Acting Local Anesthesia, and Traditional Care for Pain Control of Operatively Treated Ankle Fractures","Inclusion Criteria:\n\n* Sustained a bimalleolar ankle fracture (OTA\u002FAO type 44 A2, B2, C1, and C2 fracture) with surgery indicated and an approach with medial and lateral incisions planned Syndesmotic injuries will be included, due to the practical difficulty of reliably determining the presence of a syndesmotic injury preoperatively Trimalleolar ankle fractures where fixation of the posterior malleolus is not planned will also be included\n* Isolated Injury\n\nExclusion Criteria:\n\n* Unifocal malleolar fractures\n* Bimalleolar fractures where fixation of only one malleolus is planned\n* Posterior malleolus fractures requiring fixation\n* Patients ineligible for a peripheral nerve block (e.g. concern for compartment syndrome)\n* Open injury\n* Patients treated with external fixation\n* Neurologic condition that would confound results (e.g. peripheral neuropathy)\n* Inability to consent\n* Chronic opioid use\n* History of opiate abuse\n* Polytrauma as defined as additional boney injury, visceral injury or moderate soft tissue injury (requiring suture repair or other invasive procedure)\n* Prisoners (unlikely to be accessible for follow-up)\n* Pregnant patients\n* Non-English-speaking subjects (post-operative data collection procedure involves conversations via phone calls. As we do not have access to translators for this research project, we will work exclusively with English-speaking subjects).\n* Subjects unable to take the standard post-operative pain regimen that consists of gabapentin, oxycodone, acetaminophen, and ibuprofen.","89 Years",{"count":316,"type":20},70,[318],"PHASE4","This project is a multicenter, three armed, prospective randomized control trial studying the effectiveness of a long-acting local anesthetic \"cocktail\" in patients undergoing operative fixation of ankle fractures.",[24],"2025-11-03",{"date":323,"type":39},"2025-11-06",{"date":325,"type":39},"2020-09-01",{"date":327,"type":20},"2027-09-01",{"name":329,"class":46},"Lahey Clinic",{"id":331,"slug":4,"hasResults":10,"nctId":332,"briefTitle":333,"officialTitle":333,"acronym":334,"eligibilityCriteria":335,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":336,"targetDuration":4,"studyType":57,"phases":338,"briefSummary":339,"conditions":340,"keywords":341,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":343,"lastUpdatePostDateStruct":344,"startDateStruct":346,"completionDateStruct":348,"leadSponsor":350,"locationsCount":73},"100359894","NCT03966027","Immediate Vs. Delayed Weight Bearing Postoperative Protocol in Diabetic Ankle Fractures","Diabetic Ankle","Inclusion Criteria:\n\n1. Adults 18 and ove\n2. Positive for diabetes\n3. Positive monofilament test\n4. Isolated ankle fracture (non-pilon) and undergoing operative intervention within 3 weeks of fracture\n5. Weight less than 275 (124kg)\n6. Can tolerate and comply with brace\n7. No signs of pre-existing charcot arthroplasty or ankle deformity\n\nExclusion Criteria:\n\n1. Children\n2. Pregnant patients\n3. No signs of diabetes complicated by neuropathy\n4. Non-operative ankle fractures\n5. Multiple extremity injury\n6. Cannot follow post-operative protocol\n7. Chronic ankle fractures receiving surgery beyond 3 weeks of injury",{"count":337,"type":20},25,[59],"Operatively managed diabetic ankle fractures have significant risk for complications. The cause for failure is likely multifactorial, however, a component of failure has to do with an inability to process pain and pressure normally. This loss of protective sensation allows for an increase in abnormal stresses placed on the recently repaired fractures. Historically, diabetics have been kept non weight bearing for extended periods of time, which has its own functional and cardiovascular issues. The purpose of the study is to determine if a protocol of immediate weight bearing with a hindfoot offloading brace after surgically corrected ankle fracture in a diabetic patient will maintain adequate motion, have no difference in complications when compared to regular non-immediate weight bearing protocols, and lead to good outcome scores and patient satisfaction scores",[24],[342],"Diabetic Ankle Fractures","2025-08-22",{"date":345,"type":39},"2025-08-24",{"date":347,"type":39},"2020-08-01",{"date":349,"type":20},"2026-06-15",{"name":351,"class":46},"Kyle Schweser MD",{"id":353,"slug":4,"hasResults":10,"nctId":354,"briefTitle":355,"officialTitle":356,"acronym":4,"eligibilityCriteria":357,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":54,"enrollmentInfo":358,"targetDuration":4,"studyType":57,"phases":360,"briefSummary":361,"conditions":362,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":364,"lastUpdatePostDateStruct":365,"startDateStruct":367,"completionDateStruct":369,"leadSponsor":371,"locationsCount":373},"100559756","NCT06568276","The Benefit of Repairing the Deltoid Ligament in Unstable Ankle Fractures","The Benefit of Repairing the Deltoid Ligament in Unstable Ankle Fractures: Patient-reported Functional Outcome and Radiological Stability Measurements","Inclusion criteria; fluent in oral and written Norwegian language\n\n* isolated Weber type B fractures and Weber B+ posterior malleolar Mason Molloy class I.\n* Initial medial clear space (MCS)\\>=7mm or weightbearing x-ray evaluated as unstable or primary reposition after fracture dislocation.\n* Pre-injury walking ability without aids.\n\nExclusion criteria\n\n* assumed not compliant (drug use, cognitive- and\u002For psychiatric disorders).\n* previous history of ipsilateral ankle fracture or ipsilateral major ankle-\u002Ffoot surgery.\n* open fx Gustilo Anderson II or more, multi-trauma and pathologic fracture.\n* neuropathies and generalized joint disease such as Rheumatoid Arthritis or other more severe condition in same extremity\n* fixation of tibial fragment or syndesmotic screw or suture button planned prior to surgery",{"count":359,"type":20},120,[59],"Ankle fractures occur in 1 out of 800 persons a year and is a common injury. The deltoid ligament is necessary for the stability of the joint and guides choice of treatment. Cadaveric studies have shown that deltoid ligament repair gives more stability than the osteosynthesis of the lateral malleolus itself. The investigators want to show if suture of the deltoid ligament in unstable ankle fractures contribute to a better functional result and\u002For prevent long term osteoarthritis for our participants. Patients sustaining severe ankle fractures have shown a considerable loss of function that might affect their long term activities of daily living (ADL) function. Improving outcome for this group may preserve some patients' ability to work and reduce community expenses.",[24,363],"Deltoid Ligament; Sprain (Strain) (Ankle)","2025-08-12",{"date":366,"type":39},"2025-08-13",{"date":368,"type":39},"2024-09-20",{"date":370,"type":20},"2032-07-01",{"name":372,"class":46},"Ostfold Hospital Trust",9,{"id":375,"slug":4,"hasResults":10,"nctId":376,"briefTitle":377,"officialTitle":377,"acronym":4,"eligibilityCriteria":378,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":314,"enrollmentInfo":379,"targetDuration":4,"studyType":57,"phases":381,"briefSummary":382,"conditions":383,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":390,"lastUpdatePostDateStruct":391,"startDateStruct":393,"completionDateStruct":395,"leadSponsor":397,"locationsCount":73},"100473520","NCT05445960","Correlation Between Intraoperative Tourniquet Use and Limb pH, Functional Measures and Patient-reported Outcomes After Ankle Fracture Surgery","Inclusion Criteria:\n\n* Adult patients (18 years to 89 years) undergoing surgical ankle fracture fixation at OHSU\n\nExclusion Criteria:\n\n* sepsis\n* other significant long bone or internal injuries (including ipsilateral limb injuries).",{"count":380,"type":20},390,[59],"This study aims to 1) characterize skeletal muscle pH during\u002Fafter tourniquet use and 2) investigate any relationship between intraoperative tourniquet use and postoperative functional measures and patient-reported outcomes.",[24,384,385,386,387,388,146,389],"Ankle Fracture - Lateral Malleolus","Ankle Fracture, Bimalleolar","Ankle Fracture, Trimalleolar","Ankle Fracture - Medial Malleolus","Maisonneuve's Fracture","Fibula Fracture","2025-03-19",{"date":392,"type":39},"2025-03-24",{"date":394,"type":39},"2021-08-17",{"date":396,"type":20},"2027-03-17",{"name":398,"class":46},"Oregon Health and Science University",{"id":400,"slug":4,"hasResults":10,"nctId":401,"briefTitle":402,"officialTitle":402,"acronym":4,"eligibilityCriteria":403,"healthyVolunteers":10,"sex":16,"minAge":404,"maxAge":4,"enrollmentInfo":405,"targetDuration":4,"studyType":57,"phases":406,"briefSummary":407,"conditions":408,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":409,"lastUpdatePostDateStruct":410,"startDateStruct":412,"completionDateStruct":414,"leadSponsor":416,"locationsCount":4},"100554254","NCT06496698","Impact of Suture Technique on Wound Healing in Ankle Fracture Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 21 years or older with isolated ankle fractures requiring surgical intervention and who consent to participate.\n\nExclusion Criteria:\n\n* Patients that will be excluded from this study include those with complex ankle fractures, open fractures, a history of wound healing disorders, and\u002For those unable to provide consent.","21 Years",{"count":81,"type":20},[59],"Our primary aim is to compare the complication rates of patients with ankle fractures who underwent skin closure using a running subcuticular suture pattern compared to an interrupted suture pattern. At the time of the operation, participants will be assigned to either the Subcuticular Suture Group (SSG) or the Simple Interrupted Suture Group (SISG) using computer-generated randomization programs. The surgeon will perform the assigned closure technique using standardized techniques. Running subcuticular Vicryl 3-0 sutures will be placed on patients in the experimental group while simple interrupted Monocryl 3-0 sutures patients in our control group.\n\nPatients will be followed up at the two-week and eight-week postoperative mark where we will use the Patient and Observer Scar Assessment Scale (POSAS) to evaluate and compare wound healing. Additionally, photographs of the scars will be captured to visually assess the healing progression.",[24],"2024-07-03",{"date":411,"type":39},"2024-07-11",{"date":413,"type":20},"2024-07-15",{"date":415,"type":20},"2026-07-15",{"name":417,"class":46},"University of Puerto Rico",{"id":419,"slug":4,"hasResults":10,"nctId":420,"briefTitle":421,"officialTitle":421,"acronym":4,"eligibilityCriteria":422,"healthyVolunteers":10,"sex":16,"minAge":423,"maxAge":4,"enrollmentInfo":424,"targetDuration":4,"studyType":57,"phases":425,"briefSummary":428,"conditions":429,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":430,"lastUpdatePostDateStruct":431,"startDateStruct":433,"completionDateStruct":435,"leadSponsor":436,"locationsCount":4},"100539395","NCT06303284","Post-surgical Outcomes With Anabolic Agent Use in High-risk Ankle Fractures: A Pilot RCT","Inclusion Criteria:\n\n* Our study will include men and women over 60 years of age presenting to the emergency department with low energy ankle fractures (fall from standing height) requiring surgical treatment and who have one or more of the following risk factors, diabetes, osteoporosis, renal disease, steroid use, smoking history, peripheral neuropathy and\u002For vascular disease.\n\nExclusion Criteria:\n\n* Individuals will be excluded if they have received previous Teriparatide therapy, or they have hypercalcemia or hyperparathyroidism, as these are precautions to the use of Teriparatide.","60 Years",{"count":81,"type":20},[426,427],"PHASE1","PHASE2","As the global population ages and the prevalence of poor bone health increases among older patients with ankle fractures, so does the risk of post-surgical complications. Prevention of post-surgical complications is of paramount importance to reducing morbidity, mortality, and healthcare costs.\n\nThere is growing evidence to support the use of bone-building medications, such as Teriparatide, in patients who have delayed fracture healing or non-unions; however, these medications have yet to be investigated in elderly patients with ankle fractures at high risk for delayed fracture healing and post-operative complications. This project aims to assess the safety and efficacy of short-term Teriparatide use in improving outcomes in a population most likely to suffer post-operative complications.\n\nThe proposed study is a pilot randomized controlled trial (RCT) with patients 60 years or older with an additional risk factor for delayed healing (i.e., osteoporosis, diabetes, vascular disease) who require ankle fracture surgery. Participants will be randomized to receive the study medication (Teriparatide) or placebo for three months. The primary objective of this study is to acquire vital data (i.e., recruitment rates, follow-up rates, adherence to treatment assignment) required to determine the feasibility of a full-scale multi-centre RCT. Additional aims are to evaluate repeat surgery, complications, time-to-union, and 90-day mortality. A complete a socio-economic and feasibility analysis will be completed.\n\nThis study will evaluate the novel clinical approach of augmenting surgical fixation with a medication to build bone density and strength, thereby improving bone health, preventing complications, and improving outcomes. This study will also inform planning for a larger clinical trial to reduce the morbidity, mortality, and cost associated with complications in this high-risk population.",[24],"2024-03-15",{"date":432,"type":39},"2024-03-18",{"date":434,"type":20},"2025-01-01",{"date":70,"type":20},{"name":437,"class":46},"University of Calgary",{"id":439,"slug":4,"hasResults":10,"nctId":440,"briefTitle":441,"officialTitle":442,"acronym":443,"eligibilityCriteria":444,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":54,"enrollmentInfo":445,"targetDuration":4,"studyType":57,"phases":447,"briefSummary":448,"conditions":449,"keywords":452,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":459,"lastUpdatePostDateStruct":460,"startDateStruct":462,"completionDateStruct":464,"leadSponsor":466,"locationsCount":73},"100471041","NCT05413707","Weber B Ankle Fractures With Associated Posterior Malleolus Fracture","Posterior Malleolus Fractures (PMF) in Weber B Ankle Fractures - Fixation Versus no Fixation - a Randomized Controlled Trial","PMFIX","Inclusion Criteria:\n\n* Posterior malleolar (PM) fracture, of Mason \\& Molly type 2A\u002F2B, associated with Weber B lateral malleolar fracture, with or without medial malleolar fracture\n* Posterior malleoli \\>=2 mm displaced (on CT in axial, sagital or coronal plane)\n* Patients informed, written consent\n* Age 18-65 years\n* For inclusion axial CT images are examined\n\n  * Measurements are performed 5 millimeters (mm) cranial to the tibia plafond\n  * Posterior malleolus fractures involving less than 40% of the fibular notch are included.\n\nExclusion Criteria:\n\n* Non-compliant patient, i.e.: dementia, alcohol- or substance abuse\n* ASA-4 patients\n* Known congenital bone decease\n* Pathological fractures\n* Immunocompromised patients\n* Tourists or patients on a short-term work\u002Fstudy permit\n* Previous injury or condition of the ipsilateral ankle or ipsilateral lower extremity with a resulting dysfunction\n* Poor controlled diabetes\n* Patients with known arterial insufficiency\n* Open fractures\n* Severely traumatized patients (ISS\\>16)\n* Patient declines to participate in study",{"count":446,"type":20},198,[59],"Ankle fractures constitute 9% of all fractures and have an incidence of approximately 187 per 100,000 persons per year in Norway. A posterior malleolar fragment (PMF), located on the lower backside of the tibia, is present in up to 46% of Weber B. Weber B fractures are the most common type of fractures of the fibula, located at the height of the syndesmosis. Patients with a PMF were recently shown to have significantly lower patient-reported outcome measures (PROM) than the general population. For this reason, the indication and choice of intervention for these fractures have been the object of increased interest over the recent years. It is one of the most debated areas within ankle fracture surgery. Traditionally, these PMFs have been treated with closed reduction, without direct manipulation of the PMF, anteroposterior screw fixation, or even no-fixation of the smaller fragments. A more novel posterior approach to the ankle for open reduction and internal fixation is increasingly popular and has led to fixation of smaller and medium-sized PMFs. Studies suggest fracture reduction is better with a posterior approach. However, there is no consensus as to what the best treatment is. There are no available randomized controlled studies examining PROM in patients after surgery with fixation versus no fixation for the PMF.\n\nThrough a multicenter prospective randomized controlled trial initiated from Haukeland University Hospital, patients will be recruited and randomized to receive treatment with or without fixation of the PMF. Patients will be recruited at six study hospitals from all Regional Health Trusts in Norway. Treatment today is often based on local tradition and retrospective, ambiguous literature. As there is no clear evidence supporting the choice to fixate, or not fixate, the posterior malleolus fracture. The current study can contribute new knowledge and thereby contribute to an evidence-based approach to treating these patients.\n\nMason and Molly type 2A and 2B fractures will be included in the study.",[114,24,146,450,451],"Patient Reported Outcome Measure","Treatment Outcome",[453,454,455,456,457,458],"Posterior malleolus fractures","Ankle factures","Weber B fractures","Syndesmotic injuries","Fixation","Randomized Controlled Trial","2024-02-27",{"date":461,"type":39},"2024-02-29",{"date":463,"type":39},"2023-03-13",{"date":465,"type":20},"2030-12-31",{"name":467,"class":46},"Haukeland University Hospital",{"id":469,"slug":4,"hasResults":10,"nctId":470,"briefTitle":471,"officialTitle":472,"acronym":4,"eligibilityCriteria":473,"healthyVolunteers":10,"sex":16,"minAge":474,"maxAge":4,"enrollmentInfo":475,"targetDuration":4,"studyType":57,"phases":477,"briefSummary":478,"conditions":479,"keywords":481,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":486,"lastUpdatePostDateStruct":487,"startDateStruct":489,"completionDateStruct":491,"leadSponsor":493,"locationsCount":4},"100522715","NCT06086223","Functional Outcomes Following Ankle Fracture Fixation With or Without Ankle Arthroscopy","Functional Outcomes Following Ankle Fracture Fixation With or Without Ankle Arthroscopy: Randomized Control Study","Inclusion Criteria:\n\n* Patients ≥16 years of age who will be managed operatively for:\n\n  * rotational ankle fracture Danis-Weber classification B or C fibula fracture\n  * fracture dislocation ankle\n  * Fractures extending into the tibial plafond,\n  * Talus fractures (body or neck) in our institution\n\nExclusion Criteria:\n\nPediatric fractures, Polytrauma patients, Fractures managed with closed-contact casting and, patients with lost follow up during this study","16 Years",{"count":476,"type":20},176,[59],"The aim of our study is to identify if there is statistically significant difference in patient reported functional outcomes in cases of unstable ankle fracture managed by ORIF with and without ankle arthroscopy.",[24,25,480],"Arthroscopic Surgery",[482,483,484,485],"functional outcomes of ankle fracture management","ankle scope","syndesmosis reduction","ankle ligaments evaluation","2023-10-13",{"date":488,"type":39},"2023-10-17",{"date":490,"type":20},"2023-11-01",{"date":492,"type":20},"2026-07-30",{"name":494,"class":46},"Assiut University",""]