[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anterior-knee-pain-syndrome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anterior-knee-pain-syndrome":147},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,53,73,96,127],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":33,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100644562",false,"NCT07671482","Effects of Kinesio Taping Versus McConnell Taping on Clinical Outcomes in Patients With Patellofemoral Pain Syndrome.","Effects of Kinesio Taping Versus McConnell Taping on Clinical Outcomes in Patients With Patellofemoral Pain Syndrome. A Randomized Clinical Trial.","PFPS","Inclusion Criteria:\n\n* Anterior or retropatellar pain for a minimum of 3 months during functional activities.\n* 18-50 years of age.\n* Minimum pain of 3\u002F10 on the VAS score.\n* No LL physical therapy in the past 3 months.\n\nExclusion Criteria:\n\n* Meniscal or ligamentous injury\n* Neurological or systemic conditions affecting proprioception, coordination and balance.\n* Spinal referred pain or rheumatoid arthritis.\n* Hip and ankle disorders.","ALL","18 Years","50 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","The primary goal of this randomized clinical trial (RCT) is to evaluate whether Kinesio Taping versus McConnell Taping, when integrated into a standardized hip-knee strengthening and neuromuscular control program, produces significant effects in individuals aged 18-50 with patellofemoral pain syndrome (PFPS).\n\nThe main question it aims to answer is: Does Kinesio Taping compared with McConnell Taping when both combined with a standardized hip-knee exercise program, produce different effects on quadriceps neuromuscular activation (VMO-VL sEMG), pain, functional knee pain, and dynamic knee valgus over a 6 week period intervention?\n\nParticipants will be divided into three groups for comparison: the control group will receive a structured hip-knee physical therapy exercise program without any taping intervention, Kinesio Taping group with a standardized exercise program, and a McConnell Taping group with a standardized exercise program.",[27,28,14,29,30,31,32],"Patello Femoral Pain Syndrome","Anterior Knee Pain Syndrome","Patellofemoral Pain Syndrome","Patellofemoral Disorder","Patellofemoral Pain, PFP","Patellofemoral Pain (PFPS)",[34,35,36,37,38,29,39],"Electromyography","EMG","Kinesio Taping","McConnell Taping","Exercise Therapy","Single-Leg Squat","RECRUITING","2026-06-25",{"date":43,"type":44},"2026-06-26","ACTUAL",{"date":46,"type":21},"2026-06",{"date":48,"type":21},"2026-10",{"name":50,"class":51},"Cairo University","OTHER",1,{"id":54,"slug":4,"hasResults":10,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":52},"100277373","NCT02890485","The Effects of Dry Needling on Patients With Knee Pain","Inclusion Criteria:\n\n* 18-40 years-of-age\n* Referred for physical therapy\n* Presence of anterior knee pain around the patella during ascending\u002Fdescending stairs, squatting, and\u002For running for at least 3 months.\n\nExclusion Criteria:\n\n* Unable to provide consent\n* Bilateral patellofemoral pain syndrome\n* Received previous dry needling treatments\n* Pregnancy\n* History of pain less than 3 months\n* Imaging demonstrating the presence of confounding internal abnormality (e.g. chondral defects, ligamentous injury, and\u002For meniscal pathology),\n* Patellar instability\n* Presence of a neurological condition that would affect movement\n* Contraindications to dry needling techniques (e.g. a history of bleeding disorders, phobia of needles, an active cancer diagnosis, and presence of other systemic illness such as fever or signs of infection)\n* Actively receiving treatment for knee pain outside of the current study protocol while enrolled in the study;\n* received active and supervised PT treatment for knee pain within the last 4 weeks;\n* history of knee surgery less than 6 months ago\n* history of surgical correction of the patellofemoral complex (e.g. MPFL reconstruction, patellar realignment surgery, etc)","40 Years",{"count":60,"type":21},120,[24],"This study is testing the effectiveness of \"dry needling\" for pain management and on muscle strength and leg function for those with knee pain. Dry needling consists of small, monofilament needles that are administered directly into the tissue and manipulated to make the muscle relax for pain relief. This technique is used to treat dysfunctions in skeletal muscle and connective tissue to help diminish pain, reduce impairments of body structure and restore function.",[29,28],"2026-02-23",{"date":66,"type":44},"2026-02-25",{"date":68,"type":44},"2016-08",{"date":70,"type":21},"2030-12",{"name":72,"class":51},"Ohio State University",{"id":74,"slug":4,"hasResults":10,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":10,"sex":16,"minAge":79,"maxAge":18,"enrollmentInfo":80,"targetDuration":81,"studyType":82,"phases":4,"briefSummary":83,"conditions":84,"keywords":85,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":92,"leadSponsor":94,"locationsCount":4},"100585591","NCT06904352","Reliability and Validity of Physical Tests and Musculoskeletal Ultrasound As an Add-on in Classifying Anterior Knee Pain","AKP","Eligibility criteria are subjects, aged 7 to 50 years, with clinically confirmed non-traumatic anterior knee pain (AKP). Subjects must be able to read, understand, and speak Dutch. Before participation, the study protocol was expressed verbally and in writing, and subsequently informed consent was obtained. In addition, we assessed whether participants did understand it.\n\nInclusion Criteria:\n\n* All consecutive patients presenting clinical symptoms of AKP were screened for eligibility.\n\nExclusion Criteria:\n\n* patients with knee effusion, patients having patella instability, surgeries or previous fractured knee joint in the past, systemic pathology including inflammatory joint disease, and patients with interventions in the last three months including corticosteroid injection or physiotherapy.","7 Years",{"count":20,"type":21},"1 Day","OBSERVATIONAL","Musculoskeletal ultrasound (MSU) or sonography is a non-invasive diagnostic technique and can extend the clinical examination of Anterior Knee Pain by visualizing musculoskeletal pathology to detect invisible flaws, it is safe, cheap and easy to use in primary care and therefore ensuring substitution of care. The European Society of Musculoskeletal Radiology (ESSR) has concluded that MSU can accurately classify APK pathologies. Protocol-based MSU can detect pathologic changes including cartilage swelling, fragmentation of the tibial tubercle ossification center, patellar tendon lesions, and reactive bursitis of the deep or superficial tibial patellar bursae and is increasingly used by physical therapists in the diagnostic process.\n\nIt is hypothesized that the validity of the physical examination is insufficient to accurately classify different conditions in AKP in patients aged 7-50 years. Therefore the use of MSU as an add-on is essential.\n\nThe purpose of this study is at first to assess the validity of the physical examination and second to evaluate the inter-rater reliability of protocol-based MSU and physical examination, in patients with AKP, in primary care physiotherapy.\n\nThe study is a cross-sectional observational study with four measurements within 60 minutes, without any intervention, performed with a single-gate diagnostic design with the same eligibility criteria for all participants including one group for comparison and measurement. The Strengthening the Reporting of Observational Studies in Epidemiology Statement was used as a guideline.",[28],[86],"musculoskeletal ultrasound-physical tests-anterior knee pain-reliability","NOT_YET_RECRUITING","2025-03-24",{"date":90,"type":44},"2025-04-01",{"date":90,"type":21},{"date":93,"type":21},"2025-10-01",{"name":95,"class":51},"Vrije Universiteit Brussel",{"id":97,"slug":4,"hasResults":10,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":101,"eligibilityCriteria":102,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":103,"enrollmentInfo":104,"targetDuration":4,"studyType":22,"phases":106,"briefSummary":107,"conditions":108,"keywords":112,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":52},"100580096","NCT06832852","Which Model of Care is the Most Cost-effective in the Treatment of Musculoskeletal Disorders?","Is a Stepped Model of Care Cost-effective Compared to Usual Care for Musculoskeletal Disorders? a Randomized Controlled Trial","Edu1st","Inclusion Criteria:\n\n* present with one of the four targeted MSKDs (low back pain, neck pain, anterior knee pain, rotator cuff-related shoulder pain).\n* have had pain for at least 6 weeks.\n* For low back pain (LBP): 1) non-specific LBP with or without radiation to the lower limbs, 2) minimal score of 15 on the ODI.\n* For neck pain : 1) non-specific neck pain with or without radiation to the upper limbs, 2) minimal score of 21 on the NDI.\n* For anterior knee pain : 1) anterior knee pain during walking, running or going up or down stairs, or during at least two activities among: kneeling, squatting, and resisted knee extension, 2) maximum score of 79 on the KOS-ADL.\n* For rotator cuff-related shoulder pain : 1) minimal score of 15 on the QuickDASH, and 2) shoulder pain attributed to a rotator cuff-related shoulder pain using diagnostic guidelines of the British Elbow and Shoulder Society.\n\nExclusion Criteria:\n\n* Unavailable to participate during the 24 weeks of the study.\n* Do not understand French or English.\n* Diagnosis of rheumatoid, inflammatory or neurodegenerative diseases.\n* Received a corticosteroid injection in the previous 3 months.\n* Cognitive problems interfering (Mini-Mental State Examination ≥ 24).\n* Received a corticosteroid injection in the previous 3 months.\n* Less than 6 weeks since an intervention for their condition (including performing prescribed condition-specific exercises or taking prescribed medication).\n* For low back pain (LBP): 1) LBP related to specific conditions (e.g., vertebral fracture, infections, neuropathic pain \\[\\>4 at the DN4 questionnaire\\]), 2) history of spine surgery or signs of upper motor neuron lesions (bilateral paresthesia, hyperreflexia or spasticity)..\n* For neck pain : 1) neck pain related to specific conditions (e.g.; vertebral fracture, infections, neuropathic pain \\[\\>4 at the DN4 questionnaire\\]), 2) history of spine surgery or signs of upper motor neuron lesions.\n* For anterior knee pain : 1) history of knee surgery or patellar dislocation, 2) pain believed to originate either from meniscus or from any knee ligament.\n* For rotator cuff-related shoulder pain : 1) history of shoulder surgery, dislocations, fractures or capsulitis, 2) full thickness rotator cuff tear identified by imagery or clinical tests (lag signs and gross weakness).","65 Years",{"count":105,"type":21},369,[24],"As musculoskeletal disorders (MSKDs) reach epidemic proportions in Canada, access to the public health system for those who suffer from them is increasingly difficult. One of the main barriers is the delays to see a publicly funded health professional. New models of care must therefore be developed to ensure better access. We have previously shown that not all patients with a MSKD need to be closely followed by a health professional as for a large proportion of patients simply educating them is enough to resolve their MSKD. A stepped care model where education would be given first before deciding if patients need a more extensive follow-up should be explored. This project will compare the effectiveness of a Stepped Care Model to that of the two most widely used models of care: Usual Medical Care and Usual Rehabilitation Care. We think that a Stepped Care Model will be as effective to reduce functional limitations, but will lead to lower healthcare costs.\n\nAdults (n=369) with a MSKD will be randomly assigned to one of the intervention groups: Stepped Care, Usual Medical Care (physician-led intervention: e.g., advice\u002Feducation, pharmacological pain management), or Usual Rehabilitation Care (physiotherapist-led intervention: e.g., advice\u002Feducation, exercises). Participants in the Stepped Care Group will take part in two education sessions during the first 6 weeks. After 6 weeks, those who still have clinically important symptoms will receive follow-up rehabilitation interventions, while those who don't will be considered recovered and will have no further intervention. Primary (functional limitations) and secondary (e.g., pain, quality of life) outcomes will be assessed at baseline, and at 6, 12 and 24 weeks, and costs estimate will be established for each model of care. Knowing the urgent need for an overhaul of services to reduce wait times, the Stepped Care Model proposed could be a solution to improve access to health services without compromising quality of care.",[109,110,28,111],"Low Back Pain","Neck Pain","Rotator-cuff Related Shoulder Pain",[113,114,115,116,117],"Stepped-Care","Rehabilitation","Musculoskeletal Disorders","Education","Medical Care","2025-02-11",{"date":120,"type":44},"2025-02-18",{"date":122,"type":44},"2025-01-31",{"date":124,"type":21},"2028-07-31",{"name":126,"class":51},"Laval University",{"id":128,"slug":4,"hasResults":10,"nctId":129,"briefTitle":130,"officialTitle":130,"acronym":4,"eligibilityCriteria":131,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":132,"enrollmentInfo":133,"targetDuration":4,"studyType":22,"phases":135,"briefSummary":136,"conditions":137,"keywords":4,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":52},"100494147","NCT05714397","Effectiveness of Cingal™ for Improving Pain Scores and Function in Anterior Knee Pain","Inclusion Criteria:\n\n* Age 18 - 35 years\n* Standard weight-bearing AP and skyline view knee x-rays\n* Retropatellar or peripatellar knee pain for a minimum of 2 months\n* Confirmed diagnosis of AKP that has failed to improve with a minimum of 6 weeks of conservative treatment (activity modification, supervised physiotherapy, exercise therapy, taping or bracing, NSAIDS)\n* Pain aggravated by at least two of the following patellofemoral joint loading activities: squatting, running, ascending or descending stairs, or sitting with prolonged knee flexion.\n\nExclusion Criteria:\n\n* X-ray evidence of knee osteoarthritis or fracture\n* Meniscal or ligamentous injury assessed or suspected on clinical examination\n* Previous knee surgery\n* History of patellar instability\n* Any contraindication to knee injection (overlying skin condition, joint infection, significant joint effusion, coagulopathy, previous adverse reaction, etc.)\n* Known allergy to Cingal™ or its constituents\n* Previous knee injection within the last 3 months\n* BMI greater than 30 kg\u002Fm2\n* Diabetes, inflammatory conditions (rheumatologic disease, ankylosing spondylitis), or concurrent medical conditions which may result in chronic pain or altered pain sensation\n* Pregnant or breastfeeding\n* Workers Compensation Board case\n* Patient involved in litigation","35 Years",{"count":134,"type":21},24,[24],"Anterior Knee Pain (AKP) is a common condition that can be challenging to treat effectively. The main goal of treatment regimens is to improve the function of the knee. However, treatment can be challenging due to the knee pain experience. Cingal™ contains hyaluronic acid (HA), which acts as a joint lubricant, and the corticosteroid triamcinolone hexacetonide (TH). Some studies have shown that Cingal™ can improve joint function and provide short-term pain relief.",[28],"2025-02-03",{"date":140,"type":44},"2025-02-05",{"date":142,"type":21},"2026-04",{"date":144,"type":21},"2026-11",{"name":146,"class":51},"Banff Sport Medicine Foundation",""]