[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"avoidant-restrictive-food-intake-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:avoidant-restrictive-food-intake-disorder":77},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100593478",false,"NCT07006961","Scalable, Clinician-Supervised Generative-AI Food-Chaining Assistant for Pediatric ARFID","Scalable, Clinician-Supervised Generative-AI Food-Chaining Assistant for Pediatric ARFID: A Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n* Children must be aged 3-17 years\n* Children must have caregiver- or participant-reported DSM-5 ARFID diagnosis and\u002For EDYQ-screen-positive Avoidant Restrictive Food Intake Disorder\n* English proficiency.\n\nExclusion Criteria:\n\n* Lack of English proficiency \\[As there is no validated non-English version of the NIAS, we must exclude caregivers who do not have English proficiency\\]\n* Participants must not have been previously treated at Boston Children's for ARFID","ALL","3 Years","17 Years",{"count":19,"type":20},125,"ESTIMATED","INTERVENTIONAL",[23],"NA","Children with Avoidant\u002FRestrictive Food Intake Disorder (ARFID) often lack access to specialty dietitians, and scalable nutritional guidance\u002Ffood chaining tools are currently not available. The investigators will evaluate a web-based, clinician-supervised, generative-AI assistant that produces individualized food-chaining plans.\n\nDevelop an AI assistant that generates ≥15 allergy-safe, evidence-based chaining steps per participant and meets ≥90 % expert agreement for safety\u002Fappropriateness.\n\nValidate the assistant against gold-standard clinician recommendations (Cohen's κ ≥ 0.80).\n\nTest clinical impact in a three-month pilot RCT (n = 96) by comparing change in Nine-Item ARFID Screen (NIAS) scores between intervention and usual-care groups.\n\nHypothesis: AI-generated plans will reduce NIAS scores by ≥3 points relative to controls.",[26],"Avoidant Restrictive Food Intake Disorder",[28,29,30],"ARFID","artificial intelligence","food chaining","NOT_YET_RECRUITING","2025-06-04",{"date":34,"type":35},"2025-06-06","ACTUAL",{"date":37,"type":20},"2025-06-15",{"date":39,"type":20},"2025-10-31",{"name":41,"class":42},"Boston Children's Hospital","OTHER",{"id":44,"slug":4,"hasResults":10,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":49,"sex":15,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100561803","NCT06594913","Eating Disorders Genetics Initiative 2","EDGI2","Inclusion Criteria:\n\n* A lifetime history of anorexia nervosa, bulimia nervosa, binge-eating disorder, avoidant restrictive food intake disorders or no history of any disordered eating behavior, based on DSM-5 criteria algorithms\n* Age 12-99 years, depending on country. (US enrollment age is 18-99)\n\nExclusion Criteria:\n\n* History of subthreshold disordered eating behaviors.",true,"12 Years","99 Years",{"count":53,"type":20},20000,"OBSERVATIONAL","The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes. The investigators are enrolling 20,000 new participants with anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), avoidant\u002Frestrictive food intake disorder (ARFID), and controls in the US, Mexico, Australia, New Zealand, Sweden, and Denmark. A primary study goal is to enroll at least 30% of participants from underrepresented groups. Participants are asked to complete a series of questionnaires and submit a saliva sample for genotyping. The goal is to better understand eating disorders and how they relate to each other so that better treatments can be developed.",[57,58,59,26],"Anorexia Nervosa","Bulimia Nervosa","Binge-Eating Disorder",[61,62,63,64,65],"severe and enduring eating disorder","genetics","mental health","disordered eating","environmental factors","RECRUITING","2025-05-30",{"date":69,"type":35},"2025-05-31",{"date":71,"type":35},"2024-10-28",{"date":73,"type":20},"2027-08-01",{"name":75,"class":42},"University of North Carolina, Chapel Hill",5,""]