[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"brain-plasticity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:brain-plasticity":76},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100636401",false,"NCT07565207","Effect of aiTBS on Intrinsic Spectral Dynamics and Task Performance","The Effect of Within-network aiTBS on Cortical Excitability, Intrinsic Oscillatory Bands, and Behavioral Task Performance","Inclusion Criteria:\n\n* Able to give their consent\n* Right-handed or ambidextrous\n\nExclusion Criteria:\n\n* Non-english speaking\n* Current or past non-anxiety-related psychiatric comorbidity.\n* Active or history of active suicidal ideation\n* Alcohol\u002Fdrug problems in the past year or lifetime alcohol or drug dependence\n* Medications that act on the central nervous system\n* History of seizure\n* History of epilepsy\n* Increased risk of seizure for any reason\n* Pregnancy, or positive pregnancy test\n* Any medical (e.g., stroke, breathing problems, motion disorders) or neurological (e.g., a significant brain injury or brain infection history that increases seizure risk) condition that increases risk for fMRI or TMS (Protocol will follow recommendations from Rossi et al. 2021 doi:10.1016\u002Fj.clinph.2020.10.003)\n* Any metal in their body which would make having an MRI scan unsafe\n* Any sort of medical implants\n* Hearing loss\n* Claustrophobia\n* orthostatic hypotension",true,"ALL","18 Years","50 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","Aim 1: Measure local shifts in cortical spectral dynamics following aiTBS. Aim 2: Measure network-specific shifts in task performance following aiTBS. Exploratory aim: Evaluate changes to resting state spectral dynamics in absence of stimulation after aiTBS.",[27],"Brain Plasticity",[29,30],"transcranial magnetic stimulation","electroencephalography","NOT_YET_RECRUITING","2026-04-27",{"date":34,"type":35},"2026-05-04","ACTUAL",{"date":37,"type":21},"2026-06-01",{"date":39,"type":21},"2030-05-30",{"name":41,"class":42},"University of Pennsylvania","OTHER",{"id":44,"slug":4,"hasResults":10,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":15,"sex":16,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100509349","NCT05912270","Orchestra in Class, a Novel Booster for Executive Functions and Brain Development in Young Primary School Children","ORBIT","Inclusion Criteria:\n\n* School grade 3P\u002F4P (3rd and 4th year of elementary school (6-8-year-old children)\n* Right-handedness\n* Sufficient Mastery of the French Language\n* Able to give oral informed consent (child)\n* Able to give written informed consent (parent)\n\nExclusion Criteria:\n\n* Non-consent (children and or parents)\n* Repeated or skipped a class with respect to standard curriculum\n* Not corrected\u002Fsevere hearing deficits\n* Not corrected\u002Fsevere vision deficits\n* Severe neurodevelopmental disorders (eg. severe dyslexia, severe ADHD)\n* Older than 7 at the beginning of the school year if 3P\n* Older than 8 at the beginning of the school year if 4P\n* Protocolled music instrumental practice in the preceding year\n* Protocolled visual arts courses in the preceding year\n* MRI incompatibility (physical or psychological)\n* Psychometric battery incompatibility (psychological)","6 Years","8 Years",{"count":52,"type":21},150,[24],"How to optimally stimulate the developing brain is still unclear. Executive functions (EF) exhibited substantially stronger far transfer effects in children who learned to play a musical instrument than in children who acquired other arts.\n\nWhat is crucially lacking is a large-scale, long-term genuine randomized controlled trial (RCT) in cognitive neuroscience, comparing musical instrumental training (MIP) to another art form and a control group. Collected data of this proposal will allow, using machine learning, to build a data-driven multivariate model of children's interconnected brain and EF development over the first 2 years of their academic curriculum (6-8 years), with or without music or other art training.",[56,57,58,59,60,27,61,62,63,64,65],"Development, Child","Executive Functions","Interventions","Music","Arts","Behavior","Brain Imaging","Magnetic Resonance Imaging","Functional Magnetic Resonance Imaging","Structural Brain Connectivity","RECRUITING","2023-12-12",{"date":69,"type":35},"2023-12-18",{"date":69,"type":21},{"date":72,"type":21},"2027-04-30",{"name":74,"class":42},"School of Health Sciences Geneva",1,""]