[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cerebral-microvascular-dysfunction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cerebral-microvascular-dysfunction":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100560632",false,"NCT06579677","PRospective Observation on CErebral microvaScular Structure and Function","PRospective Observation on CErebral microvaScular Structure and Function (PROCESS): a Population-based Prospective Cohort Study","PROCESS","Inclusion Criteria:\n\n1. Community-dwelling adults aged 50-75 years;\n2. Registered Beijing household residents or residents who can be followed up stably in their own communities for a long period;\n3. Subjects with written informed consents.\n\nExclusion Criteria:\n\n1. Residents with moderate to severe disabilities (MRS ≥3), mental illness, stroke, dementia, and other serious neurological disorders (e.g., encephalitis, Parkinson's disease, epilepsy, brain tumors, and rare genetic diseases of the nervous system);\n2. Life expectancy of ≤4 years due to serious diseases such as end-stage cancer;\n3. Contraindications to magnetic resonance imaging such as implanted devices (e.g., pacemakers, defibrillators, and others);\n4. Residents who are participating in other studies.",true,"ALL","50 Years","75 Years",{"count":21,"type":22},3500,"ESTIMATED","OBSERVATIONAL","This is a population-based prospective cohort study, aiming to assess the prevalence, distributional characteristics, and dynamic change of cerebral small vessel dysfunction in a Chinese community population using advanced vascular imaging techniques; meanwhile to investigate the effect of vascular risk factors on cerebral small vessel dysfunction, cardiovascular and cerebrovascular diseases, cognitive dysfunction, and mortality.",[26,27,28,29,30,31],"Cerebral Microvascular Dysfunction","Cerebral Small Vessel Diseases","Cognitive Dysfunction","Cerebrovascular Disorders","Cardiovascular Diseases","Population","RECRUITING","2025-01-02",{"date":35,"type":36},"2025-01-06","ACTUAL",{"date":38,"type":36},"2024-10-18",{"date":40,"type":22},"2032-10",{"name":42,"class":43},"Beijing Tiantan Hospital","OTHER",2,""]