[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"enzyme-disorder-anemia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:enzyme-disorder-anemia":51},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100608787",false,"NCT07206095","Integrative Diagnosis for SCD and Other RADs","Integrative Diagnosis of Sickle Cell Disease (SCD) and Other Rare Anemia Disorders (RADs) for Personalized Medicine","INTEGRA","Inclusion Criteria:\n\n* Patients sustaining a confirmed or suspected diagnosis of an hereditary rare hemolytic anemia:\n* Sickle cell disease\n* Thalassemic syndromes\n* Congenital dyserythropoietic anemia\n* Enzymopathy\n* Unstable Hemoblogin \u002F Altered oxygen affinity\n* Hereditary stomatocytosis\n* Hereditary pyropoikilocytosis\n* Hereditary spherocytosis with severe anemia (\\\u003C8 g\u002FdL) or inconclusive diagnosis:\n* Patient with chronic hemolytic anemia and red cell smear compatible, but with:\n* EMA binding test: inconclusive or negative\n* Genetic testing: no definitive diagnosis (VUS or no findings)\n* Not transplanted or undergoing gene therapy at the time of inclusion. Patients with graft failure without a new transplant may be included.\n\nExclusion Criteria:\n\n* Carrier traits in autosomal recessive hereditary anemias","ALL",{"count":18,"type":19},200,"ESTIMATED","OBSERVATIONAL","INTEGRA aims at enabling personalized medicine for RHADs patients by the establishment of an integrative diagnostic approach based on deep phenotypic and genetic characterization through combining new generation methodologies.",[23,24,25,26,27,28,29,30,31],"Sickle Cell Disease","Thalassaemia","Congenital Dyserythropoietic Anemia (CDA)","Enzyme Disorder; Anemia","Spherocytosis, Hereditary","Stomatocytosis","Hemoglobin Disorder","Anemia Due to Membrane Defect","Rare Anemia Disorders",[33,34,35,36,37],"SICKLE CELL DISEASE","RARE ANEMIA DISORDERS","PERSONALIZED MEDICINE","DIAGNOSIS","EKTACYTOMETRY","RECRUITING","2025-09-25",{"date":41,"type":42},"2025-10-03","ACTUAL",{"date":44,"type":42},"2020-11-13",{"date":46,"type":19},"2028-05",{"name":48,"class":49},"Hospital Universitari Vall d'Hebron Research Institute","OTHER",9,""]