[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"gastrooesophageal-junction-cancer\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:gastrooesophageal-junction-cancer":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100604555",false,"NCT07151040","Phase 1\u002F2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors","A First-in-human, Phase 1\u002F2, Multicenter, Open-label, Dose Escalation, Confirmation and Expansion Study to Evaluate the Safety, Pharmacokinetics and Antitumor Activity of TH9619 in Subjects With Advanced Solid Tumors","ODIN","Inclusion Criteria:\n\n* Must have given written informed consent\n* Histopathologically confirmed advanced cancer (colorectal cancer, head and neck squamous cell cancer, non-small cell lung cancer and gastric cancer (including gastroesophageal junction cancer))\n* Prior treatment with at least one line of cytotoxic systemic therapy for metastatic\u002Funresectable cancer\n* Adult patients (≥18 years of age)\n* Must be willing to comply with study procedures\n\nExclusion Criteria:\n\n• History or presence of any clinically significant disorders as judged by the Investigator.","ALL","18 Years",{"count":19,"type":20},43,"ESTIMATED","INTERVENTIONAL",[23,24],"PHASE1","PHASE2","This is a first in human, multi-center, open-label, dosage escalation study to determine the recommended dose range of TH9619 in subjects with advanced cancer.",[27,28,29,30,31,32],"Solid Tumor","Colorectal Cancer (CRC)","Squamous Cell Carcinoma of Head and Neck","Non-Small Cell Lung Cancer (NSCLC)","Gastrooesophageal Junction Cancer","Gastric Cancer","RECRUITING","2026-01-27",{"date":36,"type":37},"2026-01-28","ACTUAL",{"date":39,"type":37},"2025-08-22",{"date":41,"type":20},"2026-12",{"name":43,"class":44},"One-carbon Therapeutics AB","INDUSTRY",4,""]