[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"gestational-age-min-36ssw\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:gestational-age-min-36ssw":36},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":10,"sex":14,"minAge":4,"maxAge":4,"enrollmentInfo":15,"targetDuration":4,"studyType":18,"phases":4,"briefSummary":19,"conditions":20,"keywords":4,"overallStatus":24,"whyStopped":4,"lastUpdateSubmitDate":25,"lastUpdatePostDateStruct":26,"startDateStruct":29,"completionDateStruct":31,"leadSponsor":33,"locationsCount":5},"100563060",false,"NCT06611254","Quantification of Brain and Kidney Perfusion Before, During, and After Hypothermia Treatment in Neonates With Perinatal Asphyxia Using Contrast-enhanced Ultrasound","Inclusion Criteria:\n\n* Fulfillment of the inclusion criteria for hypothermia treatment according to the AWMF guideline\n* Severe acidosis (pH ≤7.0 or a base deficit ≥16 mmol\u002Fl) in umbilical cord blood or a blood sample from the first hour of life, and\n* clinical signs of moderate or severe encephalopathy (severity grade 2 or 3 according to Sarnat \\& Sarnat), and\n* postnatal age ≤6h, and\n* gestational age ≥36 weeks' gestation\n* Consent of the parents\u002Flegal guardians\n* Time 1 (before the start of hypothermia treatment)\n\n  * Informing the parents\u002Flegal guardians present on site despite an emotionally stressful situation with high individual benefit for the patient\n  * If only one parent is present and able to provide information, their consent is sufficient - the second parent is informed repeatedly when they regain the ability to provide information\n  * Information adapted to the emergency situation, addressing the personal situation and comprehensible presentation of the plan\n* Time 2 (during hypothermia treatment)\n\n  --\\>Offer of a further informative discussion\u002Frepeated explanation with the parents\u002Flegal representatives before the second measurement in order to answer any questions that may have arisen\n* Suitable acoustic window\n* Availability of the qualified examiner\n\nExclusion Criteria:\n\n* Lack of consent of at least one parent\n* Pre-existing brain malformations\n* Absence of the competent examiner","ALL",{"count":16,"type":17},20,"ESTIMATED","OBSERVATIONAL","In this clinical study vascular dynamics in the neonatal brain and kidney will be monitored by CUES and ULM before, during and after hypothermia treatment in neonates with asphyxia.",[21,22,23],"Perinatal Asphyxia","Hypothermia Treatment","Gestational Age Min. 36SSW","RECRUITING","2024-09-20",{"date":27,"type":28},"2024-09-24","ACTUAL",{"date":30,"type":28},"2024-06-24",{"date":32,"type":17},"2027-12-01",{"name":34,"class":35},"University of Erlangen-Nürnberg Medical School","OTHER",""]