[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hereditary-nonpolyposis-colon-cancer\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hereditary-nonpolyposis-colon-cancer":50},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100592160",false,"NCT06989814","Smart Measurement of Circulating Tumor DNA","Smart Measurement of Circulating Tumor DNA: a Tumor-agnostic Computational Tool to Improve Colorectal Cancer Care","SMART","Inclusion Criteria:\n\n(suspect) Lynch Syndrome carriers who:\n\n* Have proven Lynch Syndrome (MMR-gene or EPCAM mutation), or have a proven microsatellite instability high (MSI-H)tumor;\n* Are at least 18 years old; Have been diagnosed with any form of cancer at the time of inclusion, but have had no treatment yet;\n* Have granted informed consent to participate in this study.\n\nExclusion Criteria:\n\n(suspect) Lynch Syndrome carriers who:\n\n* Are unwilling to undergo extra blood sampling;\n* Are under the age of 18;\n* Have no newly diagnosed tumors at time of inclusion;\n* Have been treated for their tumor at time of inclusion;\n* Are not able to read or understand Dutch language or are mentally not capable.","ALL","18 Years",{"count":19,"type":20},50,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this study is to develop a blood-test which can detect colorectal cancer in early stages.\n\nParticipants will be asked to take an extra blood test, which will be analyzed further in the lab.",[26,27,28,29],"Colorectal Neoplasms","Colorectal Neoplasms Malignant","Colorectal Neoplasms, Hereditary Nonpolyposis","Hereditary Nonpolyposis Colon Cancer",[31,32,33,34,35,36],"Liquid Biopsy","Colorectal cancer","Early detection","Prevention","Surveillance","Screening","RECRUITING","2025-08-05",{"date":40,"type":41},"2025-08-11","ACTUAL",{"date":43,"type":41},"2025-05-16",{"date":45,"type":20},"2027-02-01",{"name":47,"class":48},"Erasmus Medical Center","OTHER",2,""]