High Risk Breast Carcinoma

2

Review clinical trials related to High Risk Breast Carcinoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer

To determine the effect of low dose azacitidine therapy on tumor infiltrating lymphocytes (TILs) in primary tumors from patients with high-risk early stage breast cancer, paired t-tests will be first used to compare TIL count in pre- and post-treatment specimens.

Participants needed: 40
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: University of Illinois at ChicagoUpdated: Jun 23, 2026Locations: 1
Eligibility criteria

Age ≥ 18 years of age at time of consent [+7]

Previous anti-cancer treatment (cytotoxic chemotherapy, immunotherapy, biologic... [+7]

Status: Recruiting

Endoscopy/Robotic Assisted Nipple Skin Sparing Mastectomy

Non-inferiority study of video-assisted (endoscopic or robotic) skin- and nipple-sparing mastectomy compared to open mastectomy. The feasibility of the technique, oncological safety and cosmetic results will be studied.

Participants needed: 126
Trial details
Age: 18+Biological sex: FemaleType: ObservationalSponsor: Alejandra García-NovoaUpdated: Feb 12, 2025Locations: 1Duration: 5 Years
Eligibility criteria

Women who require a mastectomy and who do not require skin reduction or resectio...

Sarcomas of the breast. [+7]