[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"indirect-pulp-cap\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:indirect-pulp-cap":106},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,68],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100428758",false,"NCT04863222","Clinical and Radiographic Success of MTA vs Biodentine","Clinical and Radiographic Success of Mineral Trioxide Aggregate (MTA) vs Septodont Biodentine in Primary Molars in Pulpotomy and Indirect Pulp Cap Treatments","Inclusion Criteria:\n\n* Male or female patients ages of 2 to ≤12 years.\n* Bilateral symptomatic or asymptomatic vital primary molars with caries approximating or into the pulp.\n* Patient who need a pulpotomy and\u002For indirect pulp cap treatments in two or more quadrants.\n* Parents of patients who can provide consent in English.\n* Patients who need treatment in an operating room setting at Geisinger.\n\nExclusion Criteria:\n\n* Pre-operative radiographic or clinical symptoms associated with irreversible pulpitis or necrotic pulp.\n* Radiographs not displaying furcation region of the tooth.\n* Patients with cardiac conditions who need prophylaxis for infective Endocarditis.\n* Patients with any type of cancer in the past or present.\n* Non-restorable molars.",true,"ALL","2 Years","12 Years",{"count":20,"type":21},646,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","The purpose of this prospective study is to compare the clinical and radiographic success of MTA and Biodentine as a medicament in vital pulp therapy in maxillary and mandibular primary molars in a pediatric population. There is limited research currently on Biodentine since it's a novel product. Biodentine is less expensive than MTA and does not cause discoloration like MTA. Biodentine may be an alternative medicament used for vital pulp therapy in primary molars.",[27,28],"Indirect Pulp Cap","Pulpotomy","RECRUITING","2025-12-22",{"date":32,"type":33},"2025-12-23","ACTUAL",{"date":35,"type":33},"2021-11-12",{"date":37,"type":21},"2026-12-01",{"name":39,"class":40},"Geisinger Clinic","OTHER",1,{"id":43,"slug":4,"hasResults":10,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":10,"sex":16,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":52,"briefSummary":54,"conditions":55,"keywords":56,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":41},"100607050","NCT07183514","A Study Comparing Eggshell Based and Gold Standard Materials to Heal Deep Tooth Damage in Adult Molars","Clinical and Radiographic Evaluation of Eggshell-derived Calcium Hydroxyapatite Verses Calcium Hydroxide as In-direct Pulp Capping Agent in Permanent Molars","Inclusion Criteria:\n\n1. Teeth with symptoms of reversible pulpitis.\n2. Teeth that show positive response on electric pulp testing (EPT).\n3. Teeth with caries penetrating up to three-quarters (¾) of dentine without pulp involvement.\n4. Healthy cooperative patients of both sexes between 18 to 40 years of age.\n\n   \\-\n\nExclusion Criteria:\n\n1. Necrosed Teeth with radiolucency in the periapical and furcation regions.\n2. Tooth with internal and external root resorption.\n3. Periodontally compromised tooth. (BPE score 3 and above)\n4. Physically and mentally handicapped patients. (ASA score 3 and above)","18 Years","40 Years",{"count":51,"type":21},54,[53],"NA","This clinical trial will evaluate the effectiveness of eggshell-derived calcium hydroxyapatite compared to calcium hydroxide as indirect pulp capping agent in permanent teeth. A total of 54 teeth from healthy individuals aged 18 to 40 years will be randomly allocated into two groups:\n\nGroup A (experimental) treated with eggshell-derived calcium hydroxyapatite. Group B (control) treated with calcium hydroxide.\n\nAfter caries removal the assigned pulp capping agent will be applied, and the teeth will be restored. Clinical and radiographic evaluations will be performed at 1 and 3 months to assess pulp vitality, symptom-free status, and periapical health.",[27],[57],"dental caries, indirect pulp capping, hydroxyapatite, reparative dentine","NOT_YET_RECRUITING","2025-09-16",{"date":61,"type":33},"2025-09-19",{"date":63,"type":21},"2025-09-20",{"date":65,"type":21},"2026-03-31",{"name":67,"class":40},"University of Health Sciences Lahore",{"id":69,"slug":4,"hasResults":10,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":4,"eligibilityCriteria":72,"healthyVolunteers":10,"sex":16,"minAge":73,"maxAge":49,"enrollmentInfo":74,"targetDuration":4,"studyType":22,"phases":76,"briefSummary":78,"conditions":79,"keywords":89,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":41},"100584440","NCT06889363","Clinical and Radiographic Evaluation of Indirect Pulp Capping Using Platelet Rich Fibrin Versus Mineral Trioxide Aggregate in Deep Carious Molars: a Randomized Controlled Trial","Inclusion Criteria:\n\n* o Patients with asymptomatic deep carious molars.\n\n  * Patients with clinically and radiographically confirmed deep carious lesions that do not exhibit spontaneous pain.\n  * Permanent molars only.\n  * Teeth with intact or minimally restored occlusal surfaces (i.e., no extensive restorations or fractures).\n  * No history of previous endodontic treatment or direct pulp capping on the study tooth.\n  * No signs of periapical pathology based on radiographic evaluation.\n  * Patients willing to participate and follow up for 12 months.\n  * Patients who agree to return for scheduled follow-ups at 3, 6, and 12 months.\n\nExclusion Criteria:\n\n* o Patients with systemic conditions affecting bone or tissue healing (e.g., uncontrolled diabetes, osteoporosis, immunosuppressed conditions).\n\n  * Pregnant or lactating women (if applicable to your study).\n  * Teeth with pulp exposure or necrotic pulp.\n  * Presence of symptomatic irreversible pulpitis (e.g., spontaneous pain, lingering pain).\n  * Periapical pathology or internal\u002Fexternal resorption detected radiographically.\n  * Severely broken down or non-restorable teeth.\n  * Calcified root canals or excessive sclerosis that could affect pulp testing reliability.\n  * Any pre-existing root canal treatment on the selected tooth.\n  * Patients who have undergone recent fluoride treatment, pulpotomy, or other pulp therapies in the past 6 months.\n  * Patients using medications affecting bone and tissue regeneration (e.g., bisphosphonates, corticosteroids).\n  * Patients unwilling or unable to commit to the 12-month follow-up schedule.\n  * Patients with poor oral hygiene or high caries risk that could compromise treatment outcomes.","20 Years",{"count":75,"type":21},50,[77],"PHASE2","The aim of this study is the clinical and radiographic evaluation of (Platelet-Rich Fibrin (PRF) versus Mineral Trioxide Aggregate (MTA) in indirect pulp capping when used with deep carious molars over 1 year follow up.",[80,81,82,27,83,84,85,86,87,88],"Dental Caries","Pulp Caping","Indirect Pulp Treatment","Indirect Pulp Capping","Indirect Pulp Therapy","Deep Carious Lesion","Deep Carious Lesions","Molar Caries","Carious Molars",[90,91,92,93,94,95,96],"Molar caries","MTA","PRF","Indirect pulp capping","Deep carious lesion","carious molars","platelet rich fibrin","2025-03-17",{"date":99,"type":33},"2025-03-21",{"date":101,"type":21},"2025-06",{"date":103,"type":21},"2026-09",{"name":105,"class":40},"Cairo University",""]